Precision Medicine

Disease Progression and Outcomes in Patients With Benign Prostatic Hyperplasia: Protocol for a Multicenter Retrospective Cohort Study

Zexuan Lv, Jiaxing Liu, Yin Lu, Xu Zhang, Fan Gao, Bingyang Guo, Hongyu Zhang, Hongzhao Li, Chao Lv

JMIR Res Protoc 2026 (Mar 02); 15:e84965

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Localized Immune Cascade Programming in Desmoplastic Tumors: In Silico Modeling and Validation Study

Murad Novruzov, Marziyya Mammadova, Keval Raval, Waseem Ullah Khan, Ulkar Shiraliyeva

JMIRx Bio 2026 (Feb 27); 4:e85507

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Comparative Evaluation of AmnioGuard and Advanced Platelet-Rich Fibrin When Combined With NovaBone Putty in the Regeneration of Human Periodontal Infrabony Defects: Protocol for a Randomized Controlled Clinical Trial

Geeta Bhandari, Priyanka Jaiswal, Shweta Bhagat, Sakshi Kotecha

JMIR Res Protoc 2026 (Feb 26); 15:e75987

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Trends in Venture Capital Investment in AI-Driven Biopharmaceutical Startups

Abhishek Bazaz, Yunan Ji, Mariana P Socal, So-Yeon Kang

J Med Internet Res 2026 (Feb 25); 28:e84968

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Clinical, Histopathological, and Molecular Prognostic Factors Associated With Survival and Disease Progression in Adult Patients With Primary and Secondary Thyroid Lymphomas: Scoping Review Protocol

Ana M Lemos-Rodriguez, Juan Pablo Lenis-Gonzalez, Oriana Arias-Valderrama, Elizabeth Arrieta, Guillermo Edinson Guzman, Andres Octavio Garcia

JMIR Res Protoc 2026 (Feb 20); 15:e73164

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Screening for Clinically Significant Nephrolithiasis Based on Simple Health Checkup Clinical and Urine Parameters in General Populations: Multicenter Machine Learning Study

Hao-Wei Chen, Pei-Siou Wei, Yu-Chen Chen, Jeng-Yih Wu, Chia-I Lin, Yii-Her Chou, Yung-Shun Juan, Wen-Jeng Wu, Chung-Yao Kao, Jung-Ting Lee

JMIR Med Inform 2026 (Feb 19); 14:e80764

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Designing a Digital Twin for the Management of Noncommunicable Diseases: Protocol for a Pilot Study and Methodology Validation

Edgar Ross, Jason Ross, Patricia Beschler, David Guydan, Robert Jamison

JMIR Res Protoc 2026 (Feb 09); 15:e75934

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Integrated Prediction System for Individualized Ovarian Stimulation and Ovarian Hyperstimulation Syndrome Prevention: Algorithm Development and Validation

Jingjing Chen, Jianjuan Zhao, Huiyu Qiu, Yanhui Liu, Yunqi Zhang, Qicheng Sun, Yan Yi, Hongying Tang, Jing Zhao, Bin Xu, Qiong Zhang, Ge Yang, Hui Li, Junjie Liu, Zhongzhou Yang, Shaolin Liang, Yanping Li, Jing Fu

J Med Internet Res 2026 (Feb 03); 28:e78245

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Machine Learning Prediction of Pharmacogenetic Testing Uptake Among Opioid-Prescribed Patients Using Electronic Health Records: Retrospective Cohort Study

Mohammad Yaseliani, Je-Won Hong, Jiang Bian, Larisa Cavallari, Julio D Duarte, Danielle Nelson, Wei-Hsuan Lo-Ciganic, Khoa Anh Nguyen, Md Mahmudul Hasan

JMIR Med Inform 2026 (Jan 21); 14:e81048

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Machine Learning Prediction Models for Preeclampsia: Systematic Review and Meta-Analysis

Lu Liu, Qixuan Zhu, Yichi Zong, Xueyuan Chen, Wei Zhang, Jun Wang

J Med Internet Res 2026 (Jan 19); 28:e78714

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Nomograms Based on X-Ray Radiomics for Predicting Pain Progression in Knee Osteoarthritis Using Data From the Foundation for the National Institutes of Health: Development and Validation Study

Yingwei Sun, Jing Liu, Chunbo Deng, Chengbao Peng, Shinong Pan, Xueyong Liu

JMIR Med Inform 2026 (Jan 14); 14:e78338

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Prognostic Value of Dynamic Lactate Dehydrogenase Trends in Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma: Retrospective Cohort Study

Baidong Zhang, Zhichao Kang, Yi Ding, Wang Jing, Alei Feng, Renya Zeng, Jianan Li, Yi Zhao, Yuanliu Nie, Wentao Zhang, Lu Sun, Zhe Yang

JMIR Cancer 2026 (Jan 14); 12:e73576

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The Role of Iron-Overloaded Macrophages in Mesenchymal Stem Cell Senescence and Anemia in Myelodysplastic Syndromes: Protocol for an In Vitro Study

Lu Bai, Fan Wang, Yaxian Jiang, Hongmei Ouyang

JMIR Res Protoc 2026 (Jan 13); 15:e77936

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Explainable AI for Predicting Mortality Risk in Metastatic Cancer: Retrospective Cohort Study Using the Memorial Sloan Kettering-Metastatic Dataset

Polycarp Nalela, Deepthi Rao, Praveen Rao

JMIR Cancer 2026 (Jan 13); 12:e74196

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Physical Activity Recommendations Tailored by a Predictive Model for Adults With High Blood Pressure: Observational Study

Yuhui Yang, Manqing Chen, Weiwei Hu, Yifan Fu, Xingyan Li, Zhenli Liao, Hongman Feng, Yaling Zhao, Leilei Pei, Baibing Mi, Fangyao Chen

J Med Internet Res 2026 (Jan 09); 28:e78492

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Technologies, Clinical Applications, and Implementation Barriers of Digital Twins in Precision Cardiology: Systematic Review

Fatemeh Sarani Rad, Ehsan Bitaraf, Maryam Jafarpour, Juan Li

JMIR Cardio 2026 (Jan 08); 10:e78499

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Automated Classification of Lymphoma Subtypes From Histopathological Images Using a U-Net Deep Learning Model: Comparative Evaluation Study

Jin Zhao, Xiaolian Wen, Li Ma, Liping Su

JMIR Med Inform 2026 (Jan 06); 14:e72679

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