Development and Validation of a Dynamic Real-Time Risk Prediction Model for Intensive Care Units Patients Based on Longitudinal Irregular Data: Multicenter Retrospective Study

Zhuo Zheng   ^{1 *} , MS ;   Jiawei Luo   ^{2 *} , PhD ;   Yingchao Zhu   ^{1 *} , MS ;   Lei Du   ¹ , MD ;   Lan Lan   ³ , PhD ;   Xiaobo Zhou   ⁴ , PhD ;   Xiaoyan Yang   ² , PhD ;   Shixin Huang   ⁵ , PhD

¹ Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, China

² West China Biomedical Big Data Center, West China Hospital of Sichuan University, Chengdu, China

³ Information Management and Data Center, Beijing Tiantan Hospital, Beijing, China

⁴ Center for Computational Systems Medicine, McWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, United States

⁵ Department of Scientific Research, The People’s Hospital of Yubei District of Chongqing City, Chongqing, China

*these authors contributed equally