Published on in Vol 27 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/67256, first published .
Noninvasive Oral Hyperspectral Imaging–Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study

Noninvasive Oral Hyperspectral Imaging–Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study

Noninvasive Oral Hyperspectral Imaging–Driven Digital Diagnosis of Heart Failure With Preserved Ejection Fraction: Model Development and Validation Study

Xiaomeng Yang   1, 2, 3 * , MD ;   Zeyan Li   1, 2, 3 * , MD ;   Lei Lei   4 * , PhD ;   Xiaoyu Shi   1, 2, 3 * , MD ;   Dingming Zhang   5 , PhD ;   Fei Zhou   6, 7 , MD, PhD ;   Wenjing Li   6, 7 , MD ;   Tianyou Xu   1, 2, 3 , MD ;   Xinyu Liu   1, 2, 3 , MD ;   Songyun Wang   1, 2, 3, 8 , MD, PhD ;   Quan Yuan   9, 10 , PhD ;   Jian Yang   6, 7 , MD, PhD ;   Xinyu Wang   8, 11 , PhD ;   Yanfei Zhong   4, 8 , PhD ;   Lilei Yu   1, 2, 3, 8 , MD, PhD

1 Cardiovascular Hospital, Renmin Hospital of Wuhan University, Wuhan, China

2 Hubei Key Laboratory of Autonomic Nervous System Modulation, Wuhan University, Wuhan, China

3 Cardiac Autonomic Nervous System Research Center, Wuhan University, Wuhan, China

4 State Key Laboratory of Information Engineering in Surveying, Mapping and Remote Sensing, Wuhan University, Wuhan, China

5 College of Geomatics, Xi'an University of Science and Technology, Xi'an, China

6 Department of Cardiology, The First College of Clinical Medical Science, Yichang Central People's Hospital, Yichang, China

7 Hubei Key Laboratory of Ischemic Cardiovascular Disease, China Three Gorges University, Yichang, China

8 Medical Remote Sensing Information Cross-Institute, Wuhan University, Wuhan, China

9 College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan, China

10 lnstitute of Molecular Medicine, Renmin Hospital of Wuhan University, Wuhan, China

11 School of Remote Sensing and Information Engineering, Wuhan University, Wuhan, China

*these authors contributed equally

Corresponding Author:

  • Lilei Yu, MD, PhD
  • Cardiovascular Hospital
  • Renmin Hospital of Wuhan University
  • No. 238 Jiefang Road
  • Wuhan, 430060
  • China
  • Phone: 86 02788041911
  • Email: lileiyu@whu.edu.cn