Multicentric Assessment of a Multimorbidity-Adjusted Disability Score to Stratify Depression-Related Risks Using Temporal Disease Maps: Instrument Validation Study

Rubèn González-Colom   ¹ , PhD ;   Kangkana Mitra   ¹ , MSc ;   Emili Vela   ^{2, 3} , MSc ;   Andras Gezsi   ⁴ , PhD ;   Teemu Paajanen   ⁵ , PhD ;   Zsófia Gál   ^{6, 7} , MSc ;   Gabor Hullam   ^{4, 7} , PhD ;   Hannu Mäkinen   ⁵ , PhD ;   Tamas Nagy   ^{4, 6, 7} , MSc ;   Mikko Kuokkanen   ^{5, 8, 9} , PhD ;   Jordi Piera-Jiménez   ^{2, 3, 10} , PhD ;   Josep Roca   ^{1, 11, 12} , MD, PhD ;   Peter Antal   ^{4 *} , PhD ;   Gabriella Juhasz   ^{6, 7 *} , PhD ;   Isaac Cano   ^{1, 12 *} , PhD

¹ Fundació de Recerca Clínic Barcelona - Institut d’Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain

² Catalan Health Service, Barcelona, Spain

³ Digitalization for the Sustainability of the Healthcare - Institut d'Investigació Biomèdica de Bellvitge, Barcelona, Spain

⁴ Department of Measurement and Information Systems, Budapest University of Technology and Economics, Budapest, Hungary

⁵ Department of Public Health and Welfare, Finnish Health and Welfare Institute, Helsinki, Finland

⁶ Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University, Budapest, Hungary

⁷ NAP3.0-SE Neuropsychopharmacology Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, Hungary

⁸ Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine at University of Texas Rio Grande Valley, Brownsville, TX, United States

⁹ Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland

¹⁰ Faculty of Informatics, Telecommunications and Multimedia, Universitat Oberta de Catalunya, Barcelona, Spain

¹¹ Hospital Clínic de Barcelona, Barcelona, Spain

¹² Faculty of Medicine, Universitat de Barcelona, Barcelona, Spain

*these authors contributed equally