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This paper is in the following e-collection/theme issue:

Viewpoints and Perspectives (631) Extended Reality, Virtual Reality and Virtual Worlds (799) Theoretical Frameworks and Concepts (373) Innovations in Clinical Trials and Research Data Management (139) Viewpoints on XR and Spatial Computing (7) Evaluation of XR and Spatial Computing (89)

Published on in Vol 25 (2023)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/45821, first published .
Medical Extended Reality Trials: Building Robust Comparators, Controls, and Sham

Medical Extended Reality Trials: Building Robust Comparators, Controls, and Sham

Medical Extended Reality Trials: Building Robust Comparators, Controls, and Sham

Authors of this article:

Susan Persky1 Author Orcid Image ;   Luana Colloca2 Author Orcid Image
Article Authors Cited by (13) Tweetations (7) Metrics

Journals

  1. Chen J, Ma Z. Understanding and Mitigating Substance Use in Social Settings with Virtual Reality: Insights from Emerging Research. Substance Use & Misuse 2026;61(1):45 View
  2. Maddox T, Sackman J, Stoudt M, Chibbaro M, Judge E, Rothery R, Donini J, Maddox R, Darnall B. Virtual reality-delivered skills-based therapy for chronic lower back pain: from proof-of-concept to FDA authorization to clinical implementation in-home and beyond. Frontiers in Virtual Reality 2025;6 View
  3. Angelone L, Koustova E. Will XR Become the Next Frontier in Healing Substance Use Disorders?. Frontiers in Virtual Reality 2026;7 View
  4. White J, Watson L, Wang Y, Colloca G, Heagerty J, Li S, Brawn B, Varshney A, Shafir R, Belleï-Rodriguez C, Colloca L. Context-dependent placebo hypoalgesia through observational learning: the role of empathy in immersive and non-immersive environments. npj Digital Medicine 2026;9(1) View
  5. Colloca L, Han A, Massalee R, Raghuraman N, Cundiff-O’Sullivan R, Colloca G, Wang Y. Telehealth virtual reality intervention reduces chronic pain in a randomized crossover study. npj Digital Medicine 2025;8(1) View
  6. Slatman S, Heesink L, Achterkamp R, Broeks J, Lemans B, de Oliveira N, Brinckate‐Oolbekkink L, Paarlberg D, Reinders‐Messelink H, ter Riet R, Stegeman M, Knoop J, Tabak M. Cluster‐Randomised Controlled Trial of At‐Home Virtual Reality for People With Chronic Musculoskeletal Pain on the Waiting List. European Journal of Pain 2025;29(6) View
  7. Tromp J, Raeisian Parvari P, Le C. Building a taxonomy for evidence-based medical eXtended Reality (MXR) applications: identifying best practices for design innovation and global collaboration. Empathic Computing 2025;1(1) View
  8. Zuo G, Wang R, Wan C, Zhang Z, Zhang S, Yang W. Unveiling the Evolution of Virtual Reality in Medicine: A Bibliometric Analysis of Research Hotspots and Trends over the Past 12 Years. Healthcare 2024;12(13):1266 View
  9. Cassidy O, Bragg M, Elbel B. Virtual Reality–Based Food and Beverage Marketing: Potential Implications for Young People of Color, Knowledge Gaps, and Future Research Directions. JMIR Public Health and Surveillance 2024;10:e62807 View
  10. Colloca L, Fava M. What should constitute a control condition in psychedelic drug trials?. Nature Mental Health 2024;2(10):1152 View
  11. Zandonai T, Chiamulera C. The Interplay Between Environment and Drug Effects: Decoding the Ecocebo Phenomenon with Virtual Technologies. Sensors 2025;25(17):5268 View
  12. Shafir R, Watson L, Felix R, Muhammed S, Fisher J, Hu P, Wang Y, Colloca L. Factors influencing the hypoalgesic effects of virtual reality. Pain 2025;166(8):1836 View
  13. Spiegel B, Rizzo A, Persky S, Liran O, Wiederhold B, Woods S, Donovan K, Sarkar K, Xiang H, Joo S, Jotwani R, Lang M, Paul M, Senter-Zapata M, Widmeier K, Zhang H. What Is Medical Extended Reality? A Taxonomy Defining the Current Breadth and Depth of an Evolving Field. Journal of Medical Extended Reality 2024;1(1):4 View