Published on in Vol 23, No 9 (2021): September

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/28766, first published .

Ruben P A van Eijk   1, 2 , PhD ;   Anita Beelen   3, 4 , PhD ;   Esther T Kruitwagen   3, 4 , MD ;   Deirdre Murray   5, 6 , PhD ;   Ratko Radakovic   7, 8, 9, 10, 11 , PhD ;   Esther Hobson   12 , PhD ;   Liam Knox   12 , PhD ;   Jochem Helleman   3, 4 , MSc ;   Tom Burke   5, 13 , PhD ;   Miguel Ángel Rubio Pérez   14 , PhD ;   Evy Reviers   15 , MSc ;   Angela Genge   16 , PhD ;   Frederik J Steyn   17, 18, 19 , PhD ;   Shyuan Ngo   18, 19, 20, 21 , PhD ;   John Eaglesham   22 , PhD ;   Kit C B Roes   23 , PhD ;   Leonard H van den Berg   1 , PhD ;   Orla Hardiman   24, 25 , MD ;   Christopher J McDermott   12 , PhD

1 UMC Utrecht Brain Centre, University Medical Centre Utrecht, Utrecht, Netherlands

2 Biostatistics & Research Support, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Netherlands

3 Department of Rehabilitation, University Medical Centre Utrecht, Utrecht, Netherlands

4 Center of Excellence for Rehabilitation Medicine, University Medical Centre Utrecht and De Hoogstraat Rehabilitation, Utrecht, Netherlands

5 Academic Unit of Neurology, Trinity College Dublin, Dublin, Ireland

6 Department of Physiotherapy, Beaumont Hospital, Dublin, Ireland

7 Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, United Kingdom

8 Euan MacDonald Centre for Motor Neuron Disease Research, University of Edinburgh, Edinburgh, United Kingdom

9 Norfolk and Norwich University Hospital, Norwich, United Kingdom

10 Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, United Kingdom

11 Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom

12 Department of Neuroscience, Sheffield Institute for Translational Neuroscien, University of Sheffield, Sheffield, United Kingdom

13 Department of Psychology, Beaumont Hospital, Dublin, Ireland

14 Servicio de Neurología, Hospital del Mar, Barcelona, Spain

15 European Organization for Professionals and Patients with ALS (EUpALS), Leuven, Belgium

16 Department of Neurology, Montreal Neurological Institute, McGill University, Montreal, QC, Canada

17 School of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, Australia

18 The Royal Brisbane and Women’s Hospital, Herston, Australia

19 Wesley Medical Research, the Wesley Hospital, Auchenflower, Australia

20 Centre for Clinical Research, University of Queensland, Brisbane, Australia

21 Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, Australia

22 Advanced Digital Innovation (UK) Ltd, Salts Mill, United Kingdom

23 Department of Health Evidence, Section Biostatistics, Radboud Medical Centre Nijmegen, Nijmegen, Netherlands

24 Department of Neurology, National Neuroscience Centre, Beaumont Hospital, Dublin, Ireland

25 FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland

Corresponding Author: