Published on in Vol 27 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/74955, first published .
Effectiveness of Gamified Teaching in Disaster Nursing Education for Health Care Workers: Systematic Review

Effectiveness of Gamified Teaching in Disaster Nursing Education for Health Care Workers: Systematic Review

Effectiveness of Gamified Teaching in Disaster Nursing Education for Health Care Workers: Systematic Review

Authors of this article:

Shiyi Bai1 Author Orcid Image ;   HuiJuan Zeng1 Author Orcid Image ;   Qianmei Zhong1 Author Orcid Image ;   Lulu Cao1 Author Orcid Image ;   Mei He1 Author Orcid Image

Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, No.12 Changjiaxiang, Mianyang, China

Corresponding Author:

Mei He, BSN


Background: With the continuous advancement of medical technology and the frequent occurrence of disaster events, the training of health care workers in disaster nursing has become increasingly significant. However, traditional training methods often struggle to engage learners’ interest and enthusiasm, making it challenging to simulate emergencies in real-life scenarios effectively. Gamification, as an innovative pedagogical approach that enhances the enjoyment and practicality of learning through the incorporation of game elements, has garnered considerable attention in the realm of disaster nursing education for health care workers in recent years. This review systematically evaluates its effectiveness and explores its advantages in improving training outcomes.

Objective: This review aims to evaluate the effectiveness of gamified teaching methodologies in disaster nursing education and to identify the outcome of 16 indicators used in existing studies.

Methods: This study was conducted following the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) guidelines, using the PICO-SD framework (Population, Intervention, Control, Outcome, Study Design) to establish the inclusion criteria. The researchers systematically searched 8 databases on February 10, 2025, including the Cochrane Library, PubMed, CINAHL (EBSCO), Embase, Web of Science, CNKI, Wanfang, and SCOPUS. Ultimately, 16 quasi-experimental studies investigating the application of gamified teaching in disaster nursing education were included in the analysis. For randomized controlled trials (RCTs), the Cochrane Risk of Bias Assessment Tool (RoB 2.0) was used for quality assessment; for quasi-experimental studies, the Joanna Briggs Institute Risk of Bias Tool for Non-Randomized Intervention Studies was used for methodological quality evaluation. Given the heterogeneity of study designs and the diversity of study indicators, this study used a narrative synthesis to integrate the findings.

Results: The studies included in this review comprised 1 RCT and 15 quasi-experimental designs. Six gamified formats exhibited positive outcomes. The effectiveness of these formats was assessed through various metrics, including theoretical knowledge (14 studies), practical skills (11 studies), learner satisfaction (9 studies), knowledge retention (4 studies), and self-efficacy (2 studies). All formats demonstrated improvements in knowledge and skills, with high levels of satisfaction reported. However, data on long-term retention were limited.

Conclusions: Gamification teaching methods have shown significant potential to enhance core competencies such as emergency response, decision-making, and teamwork in disaster nursing education and have been effective in reinforcing learning engagement through elements such as cooperation, competition, scoring, and scenario simulation. However, there is a lack of standardized assessment frameworks for skill acquisition, longitudinal studies tracking behavior in real-life scenarios, and rigorous RCTs comparing it with traditional instruction. Although the existing evidence has not systematically confirmed its full effectiveness, based on the findings, this paper provides practical recommendations for developing and implementing gamified teaching strategies in disaster nursing education to enhance students’ knowledge acquisition and practice.

Trial Registration: PROSPERO CRD420250652129; https://www.crd.york.ac.uk/PROSPERO/view/CRD420250652129

J Med Internet Res 2025;27:e74955

doi:10.2196/74955

Keywords



According to the Global Disaster Data Platform, it is projected that in 2024, approximately 20.83 million disaster events will occur globally, affecting a cumulative total of 242,061,500 individuals and resulting in direct economic losses estimated at around US $240.1 billion [Global Disaster Data Platform. 2024. URL: https://www.gddat.cn/newGlobalWeb/#/home [Accessed 2025-06-04] 1]. The frequency of both natural and anthropogenic disasters, including floods, major accidents, and terrorist attacks, not only causes significant human casualties and psychosocial trauma but also leads to systematic infrastructure degradation [Natural disasters. Centre for Research on the Epidemiology of Disasters. 2019. URL: https://www.cred.be/sites/default/files/CC58.pdf2]. Such events are often abrupt and unpredictable, with the extent of destruction frequently exceeding the capacity and resource allocation of local emergency response systems, thereby posing substantial challenges to global sustainable development goals [Climate adaptation summit: invest in early warnings and early action. China Meteorological Administration. Jan 27, 2021. URL: https://www.cma.gov.cn/en2014/news/News/202111/t20211110_4228926.html [Accessed 2024-03-31] 3,Alfred D, Chilton J, Connor D, et al. Preparing for disasters: education and management strategies explored. Nurse Educ Pract. Jan 2015;15(1):82-89. [CrossRef] [Medline]4]. In this context, enhancing disaster response capabilities has transitioned from a selective preparedness option to a mandatory requirement within the health care sector [Labrague LJ, Hammad K, Gloe DS, et al. Disaster preparedness among nurses: a systematic review of literature. Int Nurs Rev. Mar 2018;65(1):41-53. [CrossRef] [Medline]5].

As the primary human resource within the health care system, nursing workers play crucial roles in casualty classification, emergency treatment, and public health management during disaster relief efforts [Meifang Z, et al. The effectiveness of a disaster training programme for clinical nurses: a longitudinal study. J Nurs Sci. 2014;(7):69-70.6]. This necessitates that practitioners not only possess a robust foundation of medical knowledge but also demonstrate the practical ability to make rapid decisions and execute precise rescue operations in complex environments [Yu S, Fan W, Xiaohua X, et al. Comparison of the development of disaster nursing education between China and foreign countries. Chinese Nurs. 2018;18(7):884-887. [CrossRef]7]. However, significant limitations exist within the current framework of disaster care education: the traditional pedagogical approach, which emphasizes knowledge transmission, inadequately simulates the dynamic complexities of disaster scenarios. This results in notable deficiencies in knowledge transfer and the development of situational resilience [O’Connell A, Tomaselli PJ, Stobart-Gallagher M. Effective use of virtual gamification during COVID-19 to deliver the OB-GYN core curriculum in an emergency medicine resident conference. Cureus. Jun 1, 2020;12(6):e8397. [CrossRef] [Medline]8], proving insufficient to meet the rapidly escalating demand for disaster relief training [Salerno N, Papanagnou D, Mahesh P, et al. Challenging hazards amidst observational simulation in the emergency department: advancing gamification in simulation education through a novel resident-led skills competition. Cureus. Nov 8, 2018;10(11):e3563. [CrossRef] [Medline]9].

In this context, gamification—defined as the integration of game mechanics such as points, narratives, and instant feedback into educational scenarios—demonstrates significant advantages. Education research indicates that this model can markedly enhance learners’ motivation and improve knowledge retention by promoting interactivity, challenge, and immersion [Kobner S, Grassini M, Le NN, Riddell J. The challenging case conference: a gamified approach to clinical reasoning in the video conference era. West J Emerg Med. Dec 23, 2020;22(1):136-138. [CrossRef] [Medline]10-Diemer G, Jaffe R, Papanagnou D, Zhang XC, Zavodnick J. Patient safety escape room: a graduate medical education simulation for event reporting. MedEdPORTAL. Dec 27, 2019;15:10868. [CrossRef] [Medline]12]. In health care disaster education, gamified instruction has demonstrated efficacy in cultivating time-sensitive triage decision-making and optimizing cross-functional collaboration under resource constraints [Zhang XC, Diemer G, Lee H, Jaffe R, Papanagnou D. Finding the “QR” to patient safety: applying gamification to incorporate patient safety priorities through a simulated “escape room” experience. Cureus. Feb 5, 2019;11(2):e4014. [CrossRef] [Medline]13,Szeto MD, Strock D, Anderson J, et al. Gamification and game-based strategies for dermatology education: narrative review. JMIR Dermatol. Aug 30, 2021;4(2):e30325. [CrossRef] [Medline]14]. Recent studies have shown that simulating mass casualty events in tabletop games can significantly improve knowledge recall rates. The experimental group achieved long-term memory levels of up to 97% without additional learning interventions. Meanwhile, students had a very positive attitude toward this educational model [Castro Delgado R, Fernández García L, Cernuda Martínez JA, Cuartas Álvarez T, Arcos González P. Training of medical students for mass casualty incidents using table-top gamification. Disaster Med Public Health Prep. 2023;17:17. [CrossRef]15]. There is a growing international consensus that essential game elements, including achievement systems, progressive challenges, and contextualized feedback, effectively facilitate the translational application of complex nursing skills [Sanz-Martos S, Álvarez-García C, Álvarez-Nieto C, et al. Effectiveness of gamification in nursing degree education. PeerJ. Apr 15, 2024;12:e17167. [CrossRef] [Medline]16,Achatz G, Friemert B, Trentzsch H, et al. Terror and disaster surgical care: training experienced trauma surgeons in decision making for a MASCAL situation with a tabletop simulation game. Eur J Trauma Emerg Surg. Aug 2020;46(4):717-724. [CrossRef] [Medline]17].

It is important to emphasize that although the effectiveness of gamified teaching in nursing education has been preliminarily validated [McEnroe-Petitte D, Farris C. Using gaming as an active teaching strategy in nursing education. Teaching and Learning in Nursing. Jan 2020;15(1):61-65. [CrossRef]18], its implementation in disaster nursing education for health care workers is still in the exploratory stage, and its effectiveness and best practice models have not yet been fully validated. Therefore, this study will investigate the effectiveness of gamified teaching interventions in disaster nursing education and analyze the indicators to assess their effectiveness, aiming to guide instructional design and practice in related fields.


Design

The quantitative studies were systematically evaluated following the Cochrane Handbook for Systematic Reviews of Interventions, and the report adhered to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines [Higgins J, et al. Cochrane handbook for systematic reviews of interventions. Cochrane. 2024. URL: https://training.cochrane.org/handbook [Accessed 2025-06-25] 19]. The study protocol was preregistered on PROSPERO (CRD420250652129) [Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. PLoS Med. Jul 21, 2009;6(7):e1000097. [CrossRef] [Medline]20]. Ethical approval and informed consent were not necessary, as this study did not include individual patient data.

Literature Search

This study systematically searched 8 major electronic databases, including Cochrane Library, PubMed, CINAHL (EBSCO), Embase, Web of Science, CNKI, Wanfang, and SCOPUS. The search strategy was refined with the assistance of health information librarians, using Boolean logic operators to integrate index terms (including MeSH, Emtree, and CINAHL subject terms) with free text terms. The complete search strategy is detailed in

Multimedia Appendix 1

Search strategy.

DOCX File, 22 KBMultimedia Appendix 1. To prevent excessively narrowing the search scope, outcome indicators were excluded from the selection criteria for search terms. The search period was confined to the time frame from database inception to February 10, 2025, and the literature was restricted to English and Chinese. Additionally, the search was augmented by manually screening references from included studies and pertinent review literature.

Inclusion and Exclusion Criteria

To establish the framework for inclusion criteria, we used the PICO-SD model for this systematic review. The components of the study were as follows: (1) Population: nursing students or registered nurses; (2) Intervention: educational programs incorporating core gamification elements (eg, themed games, virtual reality simulations, tabletop games, escape rooms, serious games, etc); (3) Comparison: traditional teaching methods (theoretical lectures) and nongamified e-learning; (4) Outcome: knowledge acquisition, skill performance, learner satisfaction, and evaluation of teaching effectiveness; and (5) Study design: randomized controlled trials (RCTs), nonequivalent control group designs, and single-group pretest and posttest studies. Exclusion criteria comprised (1) editorials, letters, conference abstracts, dissertations, and gray literature; (2) studies focused solely on virtual simulation that lacked game mechanics; (3) mixed-sample studies involving other health care professionals or nonnursing professionals; and (4) nonempirical research designs (eg, theoretical explorations and protocol designs).

Quality Evaluation

The quality of studies included in RCTs was evaluated using the Risk of Bias Assessment Tool for Randomized Controlled Trials developed by the Cochrane Collaboration [Tufanaru C, Munn Z, et al. Chapter 3: systematic reviews of effectiveness. In: JBI Manual for Evidence Synthesis. JBI; 2020. URL: https://doi.org/10.46658/JBIMES-20-04 [Accessed 2025-06-04] [CrossRef]21]. Conversely, non-RCTs (quasi-experimental studies) were assessed for methodological quality using the Joanna Briggs Institute tool for quasi-experimental studies [Bramer W, Bain P. Updating search strategies for systematic reviews using EndNote. J Med Libr Assoc. Jul 2017;105(3):285-289. [CrossRef] [Medline]22]. The literature quality was independently evaluated for each project by 2 systematically trained researchers (SB and HZ), with any discrepancies resolved by a third reviewer.

Data Extraction

All retrieved documents were imported into EndNote 20 for deduplication and classification management [Higgins JPT, Altman DG, Gøtzsche PC, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. Oct 18, 2011;343(Oct18 2):d5928. [CrossRef] [Medline]23]. A structured data extraction form, tailored to meet the study objectives, was developed through discussions among the research team and included the following core elements: authors/year, country, study design, population and sample size, intervention, comparison, outcome, and key findings. The literature-screening process was conducted in 2 stages: initially, 2 uniformly trained researchers (SB and HZ) independently performed the initial title and abstract screening, followed by a full-text rescreening of potentially eligible literature. Any disagreements were resolved through third-party arbitration to reach a consensus. The final data extraction was carried out by 1 researcher (SB) and subsequently cross-checked by the other 2 members to ensure accuracy.

Data Synthesis

Following the search and data screening, we will organize and summarize the research data in a tabular format. First, due to the diversity of research design components and outcome measures, meta-analysis was deemed unfeasible. Therefore, we used Campbell’s narrative synthesis (synthesis without meta-analysis) to integrate the evidence [Campbell M, McKenzie JE, Sowden A, et al. Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline. BMJ. Jan 16, 2020;368:l6890. URL: http://doi:10.1136/bmj.l6890 [CrossRef] [Medline]24]. Second, the extracted data were analyzed to assess the effectiveness of interventions using various types of games, aiming to ascertain whether gamified instruction positively influenced outcomes. Finally, the extracted data were examined for indicators of effectiveness, summarizing the categories of effectiveness indicators and offering recommendations for the future implementation of gamification in disaster nursing education.


Selection Process

Following the initial screening, 246 studies were identified, of which 171 remained after deweighting. A further 117 were excluded based on the title and abstract review, leaving 54 studies. Subsequent full-text screening led to the exclusion of 40 studies due to inaccessibility, incomplete information, or irrelevance to the topic. Additionally, 3 studies were sourced from the references, culminating in the inclusion of 16 studies [Higgins J, et al. Cochrane handbook for systematic reviews of interventions. Cochrane. 2024. URL: https://training.cochrane.org/handbook [Accessed 2025-06-25] 19]. The modified PRISMA flowchart (Figure 1) delineates the comprehensive study selection process.

Figure 1. Flowchart of literature screening.

Study Characteristics

This systematic review encompasses a total of 16 research studies, published between 2010 and 2024. The fundamental characteristics of the included literature are shown in Table 1.

Table 1. Basic characteristics of included studies.
Authors/year/countryStudy designPopulation and sample sizeInterventionKey finding
Game categoryGamification elementsOutcome
Moon and Kim (2024, Korea) [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25]Quasi-experimental design—single group pre- and posttestEmergency department nurses
(n=27)
VR-MGBAa (100 minutes)
  • Points
  • Ranking
  • Feedback
  • Scenario-based exercises
  • Critical thinking
  • Triage skills
  • Triage accuracy
  • App usage details
Gamification improves emergency triage accuracy.
Wang et al (2024, China) [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26]Quasi-experimental design—single group pre- and posttestEmergency medical nurses
(n=97)
Tabletop games
(3 hours)
  • Challenges
  • Collaboration
  • Feedback
  • Map
  • Knowledge
  • Attitude
  • Feedback
Improved triage skills and motivation.
Cha and Lee (2023, Korea) [Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27]Quasi-experimental design—single group pre- and posttestClinical nurses
(n=30)
Tabletop games
(60 minutes)
  • Scenario-based exercises
  • Knowledge
Effective in improving knowledge of emerging infectious diseases.
Masoumian Hosseini et al (2023, Iran)
[Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28]
Quasi-experimental design—2 groups of pre- and posttestsNursing students
(bI=60, cC=60)
Simulation games
(2 weeks)
  • Competitive incentives
  • Scenario-based exercises
  • Feedback
  • Skills
  • Knowledge
  • OSCEd
Enhances learning sustainability when integrated with instructional practices.
Hu et al (2022, China) [Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29]Quasi-experimental design—2 pre- and posttests, final testNursing students
(I=82, C=85)
VR-MGBA
(4 hours)
  • Scenario-based exercises
  • Knowledge
  • Skills
  • Satisfaction
  • Engagement and knowledge retention
More effective than traditional lecture-based instruction.
Hu et al (2022, China) [Hu H, Liu Z, Li H. Teaching disaster medicine with a novel game-based computer application: a case study at Sichuan University. Disaster Med Public Health Prep. Apr 2022;16(2):548-554. [CrossRef] [Medline]30]Quasi-experimental design—2 pre- and posttests, final testNursing students
(I=63, C=68)
VR-MGBA
(6 hours)
  • Collaboration
  • Scenario-based exercises
  • Knowledge
  • Satisfaction
  • Engagement and knowledge retention
Effective pedagogical tool for managing patient surges.
Masoumian Hossein et al (2022, Iran) [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31]Quasi-experimental design—2 groups of pre- and posttestsNursing students
(I=30, C=30)
Theme games
(4 weeks)
  • Collaboration
  • Scenario-based exercises
  • Competition
  • Time pressure
  • Feedback
  • OSCE
  • Knowledge engagement and knowledge retention
Enhanced knowledge and behavioral fluency in crisis management.
Calik et al (2022, Turkey) [Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32]Quasi-experimental design—single-group pre- and posttestNursing students
(n=62)
Serious games
40 minutes
(1 week)
  • Scenario-based exercises
  • Knowledge
  • Feedback
Increased knowledge of infections and safe behaviors.
Chow et al (2022, China) [Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33]Quasi-experimental design—single-group pre- and posttestNursing students
(n=177)
3D games
(75 minutes)
  • Scenario-based exercises
  • Feedback
  • Competition
  • Knowledge
  • Self-efficacy
A valuable tool for managing low-probability clinical tasks.
Chang et al (2022, China) [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34]Quasi-experimental design—2 sets of repeated measurementsEmergency nurses
(I=32, C=35)
Simulation games
(40 minutes)
  • Tabletop games
  • Role-playing
  • Feedback
  • Knowledge
  • Self-efficacy
  • Engagement and knowledge retention
Quickly boosts chemical disaster preparedness.
Ma et al (2021, China) [Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35]RCTseNursing students
(I=51, C=53)
Theme games
(110 minutes)
  • Scenario-based exercises
  • Cooperation
  • Time pressure
  • Feedback
  • Cognitive skills
  • Affective
More effective than scenario simulation in improving disaster nursing competence.
Mirzaei et al (2020, Iran) [Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]Quasi-experimental study—2 pre- and posttestsClinical nurses
(I=40, C=40)
Tabletop games
(2 hours)
  • Scenario-based exercises
  • Knowledge
  • Attitude
  • Performance
  • Knowledge retention
Improves nurses’ disaster preparedness.
Husna et al (2020, Indonesia) [Husna C, Kamil H, Yahya M, Tahlil T, Darmawati D. Does tabletop exercise enhance knowledge and attitude in preparing disaster drills? Nurs Med J Nursing. Aug 27, 2020;10(2):182-190. [CrossRef]37]Quasi-experimental study—single-group pre- and posttestNursing students
(n=80)
Tabletop games
(90 minutes)
  • Scenario-based exercises
  • Role-playing
  • Knowledge
  • Attitude
Enhances knowledge and attitudes toward learning.
Fathoni et al (2019, Indonesia) [Fathoni M, Yueniwati Prabowowati Wadjib Y, Addiarto W. The effect of learning tabletop disaster exercise (TDE) to improve knowledge among nursing students for disaster emergency response. RJLS. Apr 1, 2019;6(1):29-35. URL: https://rjls.ub.ac.id/index.php/rjls/issue/view/18 [CrossRef]38]Quasi-experimental study—2 pre- and posttestsNursing students (I=18, C=18)Tabletop games
  • Scenario-based exercises
  • Role-playing
  • Knowledge
Significantly improves students’ knowledge.
Zhixia et al (2017, China) [Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39]Quasi-experimental study—2 pre- and posttestsNursing students (I=166, C=165)3D games
  • Scenario-based exercises
  • Knowledge
  • Skills
  • OSCE
Enhances students’ theoretical performance.
Knight et al (2010, United Kingdom) [Knight JF, Carley S, Tregunna B, et al. Serious gaming technology in major incident triage training: a pragmatic controlled trial. Resuscitation. Sep 2010;81(9):1175-1179. [CrossRef] [Medline]40]Quasi-experimental studyEmergency nurses
(I=47, C=44)
Serious gaming
(60 minutes)
  • Scenario-based exercises
  • Time-limited
  • Skills
Enhances learning and performance beyond traditional methods.

aVR-MGBA: virtual reality mobile game–based app.

bI: intervention group.

cC: control group.

dOSCE: Objective Structured Clinical Examination.

eRCTs: randomized controlled trials.

Among the 16 studies, geographical distribution reveals that 7 originated from China [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26,Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29,Hu H, Liu Z, Li H. Teaching disaster medicine with a novel game-based computer application: a case study at Sichuan University. Disaster Med Public Health Prep. Apr 2022;16(2):548-554. [CrossRef] [Medline]30,Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33-Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35,Fathoni M, Yueniwati Prabowowati Wadjib Y, Addiarto W. The effect of learning tabletop disaster exercise (TDE) to improve knowledge among nursing students for disaster emergency response. RJLS. Apr 1, 2019;6(1):29-35. URL: https://rjls.ub.ac.id/index.php/rjls/issue/view/18 [CrossRef]38,Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39], 3 from Iran [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36], 2 from Korea [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25,Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27], 2 from Indonesia [Husna C, Kamil H, Yahya M, Tahlil T, Darmawati D. Does tabletop exercise enhance knowledge and attitude in preparing disaster drills? Nurs Med J Nursing. Aug 27, 2020;10(2):182-190. [CrossRef]37,Fathoni M, Yueniwati Prabowowati Wadjib Y, Addiarto W. The effect of learning tabletop disaster exercise (TDE) to improve knowledge among nursing students for disaster emergency response. RJLS. Apr 1, 2019;6(1):29-35. URL: https://rjls.ub.ac.id/index.php/rjls/issue/view/18 [CrossRef]38], 1 from Turkey [Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32], and 1 from the United Kingdom [Knight JF, Carley S, Tregunna B, et al. Serious gaming technology in major incident triage training: a pragmatic controlled trial. Resuscitation. Sep 2010;81(9):1175-1179. [CrossRef] [Medline]40]. Notably, 93.75% (15/16) of the studies were conducted in Asian countries, highlighting the region’s active engagement in gamified teaching and learning. Regarding temporal distribution, only 2 studies were published between 2010 and 2018, while the number surged to 14 post-2019, indicating a significant increase in interest in gamified teaching within disaster nursing education. The study population comprised nursing students (n=1268) and registered nurses (n=392), with participant numbers per study ranging from 27 to 331, totaling 1660 participants in this systematic evaluation. Concerning game types, 6 categories of games were used in disaster nursing education, either in the intervention group or the control group. Specifically, 5 studies used tabletop games [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26,Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27,Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36-Fathoni M, Yueniwati Prabowowati Wadjib Y, Addiarto W. The effect of learning tabletop disaster exercise (TDE) to improve knowledge among nursing students for disaster emergency response. RJLS. Apr 1, 2019;6(1):29-35. URL: https://rjls.ub.ac.id/index.php/rjls/issue/view/18 [CrossRef]38], 2 used serious games [Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32,Knight JF, Carley S, Tregunna B, et al. Serious gaming technology in major incident triage training: a pragmatic controlled trial. Resuscitation. Sep 2010;81(9):1175-1179. [CrossRef] [Medline]40], 3 incorporated virtual reality mobile game−based app [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25,Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29,Hu H, Liu Z, Li H. Teaching disaster medicine with a novel game-based computer application: a case study at Sichuan University. Disaster Med Public Health Prep. Apr 2022;16(2):548-554. [CrossRef] [Medline]30], 2 used featured theme games [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35], 2 involved 3D games [Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33,Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39], and the remaining 2 used simulation games (interactive/VR) [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34]. In terms of technological trends, upper-middle-income countries demonstrate a preference for integrating VR/3D technology with game elements for educational purposes, whereas low-income countries tend to favor low-cost tabletop games.

Furthermore, among these 16 studies, 6 used a quasi-experimental 1-group pretest and posttest design [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25-Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27,Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32,Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33,Husna C, Kamil H, Yahya M, Tahlil T, Darmawati D. Does tabletop exercise enhance knowledge and attitude in preparing disaster drills? Nurs Med J Nursing. Aug 27, 2020;10(2):182-190. [CrossRef]37], 9 used a quasi-experimental 2-group pretest and posttest design [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28-Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34,Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36,Fathoni M, Yueniwati Prabowowati Wadjib Y, Addiarto W. The effect of learning tabletop disaster exercise (TDE) to improve knowledge among nursing students for disaster emergency response. RJLS. Apr 1, 2019;6(1):29-35. URL: https://rjls.ub.ac.id/index.php/rjls/issue/view/18 [CrossRef]38-Knight JF, Carley S, Tregunna B, et al. Serious gaming technology in major incident triage training: a pragmatic controlled trial. Resuscitation. Sep 2010;81(9):1175-1179. [CrossRef] [Medline]40], 1 study implemented an RCT [Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35], and 2 conducted various comparative analyses between games [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34,Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35].

Effectiveness of the Intervention

Research has shown that gamified instructional interventions exhibit differentiated characteristics in different disaster education scenarios. Tabletop games can significantly increase participants’ motivation, infectious disease awareness, and disaster care knowledge by simulating mass casualty events, infectious diseases, and natural disasters [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26,Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27,Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]. Serious games focus on reinforcing the theoretical system of disaster response capabilities by targeting the prevention of infectious diseases and the teaching of emergency triage [Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32,Knight JF, Carley S, Tregunna B, et al. Serious gaming technology in major incident triage training: a pragmatic controlled trial. Resuscitation. Sep 2010;81(9):1175-1179. [CrossRef] [Medline]40]. Virtual reality mobile game−based app optimizes disaster evacuation training by relying on virtual reality technology to effectively improve triage accuracy, disaster classification knowledge, and student satisfaction [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25,Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29,Hu H, Liu Z, Li H. Teaching disaster medicine with a novel game-based computer application: a case study at Sichuan University. Disaster Med Public Health Prep. Apr 2022;16(2):548-554. [CrossRef] [Medline]30]. The thematic game focuses on crisis management and disaster response capacity development, enhancing behavioral fluency and disaster care knowledge application through knowledge-behavior transformation mechanisms [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35]. The 3D game is based on high simulation of mass casualty and trauma scenarios, which improves ease of use and extends the knowledge dimension of disaster relief [Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33,Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39]. Simulation games (interactive or virtual reality) are used in complex scenarios such as disaster triage and chemical disasters to strengthen skills, self-efficacy, and triage knowledge through immersive training, highlighting the synergistic optimization of practical ability and psychological state empowered by technology [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34]. Table 2 summarizes the intervention effects of different types of games across various application scenarios.

Table 2. Intervention effects of different games.
ClassificationApplication scenarioEffectiveness of the interventionChallenges
Tabletop games
  • Mass casualty incidents [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26]
  • Infectious diseases [Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27]
  • Natural disasters [Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35]
  • Disaster drills [Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36,Husna C, Kamil H, Yahya M, Tahlil T, Darmawati D. Does tabletop exercise enhance knowledge and attitude in preparing disaster drills? Nurs Med J Nursing. Aug 27, 2020;10(2):182-190. [CrossRef]37]
  • Participants’ motivation to learn is fostered
  • Improved knowledge of infectious diseases
  • Increased preparedness for natural disasters
  • Improved disaster care knowledge and disaster response capacity
  • Need to coordinate multiple face-to-face participants.
  • Reliance on manual feedback and recording.
Serious games
  • Prevention of infectious diseases [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31]
  • Teaching of critical incident triage [Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39]
  • Increased theoretical knowledge of disaster care capacity
  • High technical complexity (requires IT support).
  • Interdisciplinary design team requirements.
VR-MGBAa
  • Disaster evacuation [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25,Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29,Hu H, Liu Z, Li H. Teaching disaster medicine with a novel game-based computer application: a case study at Sichuan University. Disaster Med Public Health Prep. Apr 2022;16(2):548-554. [CrossRef] [Medline]30]
  • Increased accuracy of triage
  • Increased theoretical knowledge of disaster classification
  • Increased satisfaction
  • Device penetration limitations.
  • Need for stability.
Theme games
  • Crisis and disaster management [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31]
  • Disaster care capacity [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34]
  • Increased knowledge and behavioral fluency in crisis management
  • Disaster care knowledge enhancement
  • Universal rate of equipment.
3D games
  • Mass casualty sites [Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33]
  • Trauma scene [Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39]
  • Increased perceived ease of use of the game
  • Increased knowledge of disaster response
  • Hardware compatibility issues.
Simulation games
  • Disaster site triage [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28]
  • Chemical disasters [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34]
  • Increased disaster preparedness and self-efficacy
  • Increased knowledge of disaster triage
  • Skill-level improvement
  • Difficulty of algorithms for dynamic scene generation.
  • Difficulty integrating with traditional curriculum.

aVR-MGBA: virtual reality mobile game–based app.

Indicators of Effectiveness in Reporting Outcomes

The purpose of this study was to highlight the impact of interventions and assess their effectiveness. The 16 studies included in this review assessed the effectiveness of gamified instruction through a multidimensional perspective, focusing on key indicators such as theoretical performance, skill acquisition, participant satisfaction, long-term knowledge retention, and self-efficacy.

Theoretical Knowledge

In the 16 included studies, 13 (81.3%) assessed the intervention effect of gamified instruction on theoretical knowledge through systematic measurement. The measurements were mainly based on a multistage test design, including a pretraining test, a posttest, and a final test. For example, Moon and Kim [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25] found a significant improvement in participants’ triage accuracy from a baseline level of 4.3 (SD 2.00) to 5.33 (SD 1.47) (t27=−2.18; P=.04) and a significant reduction in overtriage (t27=3.11; P=.00) by using a paired-sample 2-tailed t test. Mirzaei et al [Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36] used repeated-measures ANOVA with paired 2-tailed t tests to assess disaster care knowledge and showed that the intervention group’s disaster preparedness in terms of knowledge base, learning efficacy, and self-efficacy was significantly higher at posttest and 1-month follow-up period. A study by Chang et al [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34] further demonstrated that the intervention group had a significantly higher self-assessment score of knowledge about chemical disasters than the control group (P<.05), but this difference disappeared at 3 weeks postintervention (P>.05), suggesting a limitation in the timeliness of knowledge retention.

Practical Skills

Of the 16 included studies, 7 (43.8%) assessed skill acquisition, of which 3 (18.8% of the total) used the Objective Structured Clinical Examination (OSCE) to quantify the effect of skill acquisition [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39]. Masoumian et al [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31] assessed the intervention effect of a thematic game on nursing students’ knowledge and behavioral fluency in crisis management through repeated-measures ANOVA and paired-samples 2-tailed t test. The study used a standardized rating scale in which the trainer quantitatively rated the participants’ skill performance in the patient assessment component of the theme game. The results showed that the clinical skill scores of the intervention group were significantly higher than the baseline levels at 1 week (OSCE2: P<.001) and 1 month (OSCE3: P<.001) postintervention, suggesting significant short- to medium-term skill-enhancing effects. However, its follow-up study [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28] assessed triage skills by chi-square test with OSCE and found no significant difference between the intervention and control groups in the total score of the Triage Skills Questionnaire and scores of the 3 dimensions of Rapid Assessment, Categorization, and Patient Assignment (P>.05), suggesting that there may be a scenario-specific limitation in the effect of triage skills migration. In addition, Zhixia et al [Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39] showed that the total score of trauma scene rescue skill operation of the experimental group was significantly higher than that of the control group (P<.05), indicating that the gamification intervention has a facilitating effect on the specific skills.

Engagement and Knowledge Retention

Five studies (5/16, 31.3%) assessed engagement through satisfaction surveys, and the results showed that participants generally recognized the interactivity and fun of the gamified teaching format [Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29-Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34,Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]. However, the long-term knowledge retention effect showed heterogeneity: Chang et al [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34] found no significant difference in chemical disaster knowledge scores between the intervention and control groups 3 weeks after the simulation game intervention (P>.05), whereas Masoumian et al [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31] noted that the skill knowledge of the intervention group was still significantly higher than the baseline level at the 1-month follow-up period (P<.01), but the theoretical knowledge difference did not reach statistical significance. Such contradictions may be related to the length of the intervention, the form of the technique, and the sensitivity of the assessment tool, and further research is needed to validate them.

Self-Efficacy

Two studies indicate that self-efficacy has a significant impact on the learning and use of computers [Tzeng WC, Feng HP, Cheng WT, et al. Readiness of hospital nurses for disaster responses in Taiwan: a cross-sectional study. Nurse Educ Today. Dec 2016;47:37-42. [CrossRef] [Medline]41]. For example, the study by Chow et al [Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33] revealed that computer self-efficacy accounted for a substantial portion of the variance in perceived ease of use and perceived usefulness. Furthermore, individuals with higher self-efficacy exhibited elevated expectations for computer use, aligning with motivation theory and Bandura’s social cognitive theory [Bandura A. Social Foundations of Thought and Action. Prentice-Hall; 1986. ISBN: 978-013815614542]. The research by Chang et al [Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34] demonstrated that both virtual reality and tabletop exercises could enhance nursing professionals’ self-efficacy in responding to chemical disasters, particularly among less experienced nurses, with virtual reality notably improving their short-term self-preparedness.

Quality Evaluation Results

The methodological quality of the included studies was evaluated using the Cochrane Risk of Bias Assessment Tool and the Joanna Briggs Institute Risk of Bias in Non-Randomized Intervention Studies tool. The overall quality of the studies was found to be average. The results indicated that the sole included RCT was assessed as having a medium risk regarding randomized sequence generation and allocation concealment [Ma D, Shi Y, Zhang G, Zhang J. Does theme game-based teaching promote better learning about disaster nursing than scenario simulation: a randomized controlled trial. Nurse Educ Today. Aug 2021;103:104923. [CrossRef] [Medline]35], primarily due to the lack of information on whether the study was blinded for subjects and investigators. Among the 15 quasi-experimental studies conducted by the implementers, 11 were classified as high risk of bias [Moon SH, Kim SO. Enhancing triage accuracy in emergency nurses: the impact of a game-based triage educational app. Int Emerg Nurs. Feb 2024;72:101398. [CrossRef] [Medline]25-Cha KS, Lee K. Effect of a tabletop program for training emerging infectious disease responses in nurses at small- to medium-sized hospitals in areas with poor healthcare access. Healthcare (Basel). Aug 22, 2023;11(17):2370. [CrossRef] [Medline]27,Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29,Hu H, Liu Z, Li H. Teaching disaster medicine with a novel game-based computer application: a case study at Sichuan University. Disaster Med Public Health Prep. Apr 2022;16(2):548-554. [CrossRef] [Medline]30,Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32,Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33,Husna C, Kamil H, Yahya M, Tahlil T, Darmawati D. Does tabletop exercise enhance knowledge and attitude in preparing disaster drills? Nurs Med J Nursing. Aug 27, 2020;10(2):182-190. [CrossRef]37-Knight JF, Carley S, Tregunna B, et al. Serious gaming technology in major incident triage training: a pragmatic controlled trial. Resuscitation. Sep 2010;81(9):1175-1179. [CrossRef] [Medline]40]. This classification arose mainly from deficiencies in 9 areas, including the absence of diversified measurements for implementation outcomes, lack of a control group, or reliance on self-designed instruments for outcome indicators, which significantly heightened the risk of bias. Ultimately, only 4 of the 16 included studies were rated as low risk of bias [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34,Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]. The risk of bias graph and summary are shown in Figures 2 and Climate adaptation summit: invest in early warnings and early action. China Meteorological Administration. Jan 27, 2021. URL: https://www.cma.gov.cn/en2014/news/News/202111/t20211110_4228926.html [Accessed 2024-03-31] 3, respectively.

Figure 2. Graph and summary of the risk of bias in the randomized controlled trial studies according to the revised version of the Cochrane risk of bias tool for randomized trials [35].
Figure 3. Graph and summary of the risk of bias in the non–randomized controlled trial studies according to the Joanna Briggs Institute risk of bias in nonrandomized studies of interventions [25-34,36-40].

Principal Findings

The primary objective of this review was to assess the effectiveness of gamified instruction in disaster nursing education and its associated indicators. Although the indicators of effectiveness and the quality of the studies varied, all interventions demonstrated a positive impact on health care workers’ outcomes. Specifically, these interventions significantly improved theoretical knowledge, practical skills, engagement and knowledge retention, satisfaction with the intervention, and self-efficacy.

Current Status of Gamification

Research has shown that the use of gamified teaching methods in disaster nursing education demonstrates significant results [Yao J, Song D, Xiao T, Zhao J. Smartwatch-based tailored gamification and user modeling for motivating physical exercise: experimental study with the maximum difference scaling segmentation method. JMIR Serious Games. Apr 18, 2025;13:e66793. [CrossRef] [Medline]43,Akl EA, Pretorius RW, Sackett K, et al. The effect of educational games on medical students’ learning outcomes: a systematic review: BEME Guide No 14. Med Teach. Jan 2010;32(1):16-27. [CrossRef] [Medline]44]. However, gamification differs from digital game design in that it promotes knowledge acquisition and behavioral improvement not only through competition and reward motivation but also through contextual simulation and feedback mechanisms [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31]. Tabletop games, for example, cost less than digital games, can simulate situations repeatedly at less cost, and are easy to rehearse, with participants recognizing their roles and responsibilities, which is consistent with previous research findings [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26]. Of course, tabletop games have certain limitations. Studies have pointed out that tabletop exercises cannot replace the experience gained from actual disaster response exercises and that learners must have some prior knowledge of disaster response to achieve effective learning outcomes [Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]. Therefore, tabletop games are more appropriate for learners with some experience in disaster response, and they are not a particularly effective teaching method for less experienced nurses.

In addition, the core of digital games as complete metadata information systems lies in the systematic description and dynamic interaction of game elements through structured data models, and their design goals are more focused on constructing self-consistent virtual experiences rather than direct educational transformations [Fiellin LE, Hieftje KD, Pendergrass TM, et al. Video Game Intervention for Sexual Risk Reduction in Minority Adolescents: Randomized Controlled Trial. J Med Internet Res. Sep 18, 2017;19(9):e314. [CrossRef] [Medline]45,Caserman P, Hoffmann K, Müller P, et al. Quality criteria for serious games: serious part, game part, and balance. JMIR Serious Games. Jul 24, 2020;8(3):e19037. [CrossRef] [Medline]46]. For example, serious games and 3D video games are also effective in enhancing knowledge and skills. For less experienced nurses, these games are easy to pick up, more engaging, and can increase the cognitive load to some extent [Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33]. However, these games may also increase extraneous loads, such as prolonged engagement requiring sustained attention and endurance. While limited by device penetration and system stability, they may affect learning outcomes [Akl EA, Pretorius RW, Sackett K, et al. The effect of educational games on medical students’ learning outcomes: a systematic review: BEME Guide No 14. Med Teach. Jan 2010;32(1):16-27. [CrossRef] [Medline]44]. Therefore, although digital games can provide richer learning experiences, their implementation faces certain technical and resource challenges.

In the future, it is necessary to balance technical complexity with pedagogical use, such as optimizing cognitive load distribution through hierarchical design and developing standardized tools (eg, cross-platform simulation systems) to lower the hardware threshold, to maximize the pervasiveness and effectiveness of gamified interventions in disaster care teaching.

Outcomes and Effectiveness

Research indicates that the predominant methods for evaluating the effectiveness of gamified instruction involve comparing knowledge and skill differences between intervention and control groups, or assessing changes in knowledge preintervention and postintervention within a single group. Unlike prior reviews of gamified instruction in disaster education [Bai S, Zeng H, Zhong Q, Shen Y, Cao L, He M. Application of gamification teaching in disaster education: scoping review. JMIR Serious Games. Dec 11, 2024;12:e64939. [CrossRef] [Medline]47], the studies included in this review primarily demonstrated the effectiveness of gamified instruction by reporting levels of theoretical knowledge, whereas earlier studies emphasized the availability of game types and outcomes.

This review yields positive conclusions regarding the efficacy of gamified teaching in enhancing the theoretical knowledge and skills of nursing professionals. In 5 studies, standardized questionnaires that were tested for reliability and validity were used to measure theoretical knowledge, thereby ensuring the robustness of the assessment results [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Chang CW, Lin CW, Huang CY, Hsu CW, Sung HY, Cheng SF. Effectiveness of the virtual reality chemical disaster training program in emergency nurses: a quasi experimental study. Nurse Educ Today. Dec 2022;119:105613. [CrossRef] [Medline]34-Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]. However, some studies used self-designed questionnaires, which may complicate the comparison and interpretation of results. Consequently, future research should prioritize the use of standardized, validated assessment tools. Furthermore, 3 studies evaluated skill acquisition through the OSCE, a scientific and objective method that accurately assesses participants’ practical skills in critical areas such as triage, disaster management, and emergency response [Masoumian Hosseini M, Masoumian Hosseini ST, Qayumi K, Hosseinzadeh S, Ahmady S. Crossover design in triage education: the effectiveness of simulated interactive vs. routine training on student nurses’ performance in a disaster situation. BMC Res Notes. Nov 5, 2023;16(1):313. [CrossRef] [Medline]28,Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31,Zhixia J, et al. Application of gamification teaching method in trauma field rescue laboratory teaching. Chongqing Med. 2017;46(9):1290-1291.39]. This assessment type is crucial as it enhances the practicality and applicability of disaster nursing education. Additionally, 5 studies indicated that participants generally held a positive attitude toward the gamified teaching format, suggesting that gamified instruction possesses significant advantages in stimulating learning interest and enhancing motivation [Wang P, Chang H, Hong M, et al. Action‐time‐controlled tabletop gamification improves physician-nurse collaborative emergency room evacuation training. Contingencies & Crisis Mgmt. Mar 2024;32(1):e12537. URL: https://onlinelibrary.wiley.com/toc/14685973/32/1 [CrossRef]26,Hu H, Lai X, Li H, Nyland J. Teaching disaster evacuation management education to nursing students using virtual reality mobile game-based learning. Comput Inform Nurs. Oct 1, 2022;40(10):705-710. [CrossRef] [Medline]29,Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32,Chow MCM, Hung MSY, Chu JWK, Lam SKK. Factors affecting nursing students’ intention to use a 3D game to learn field triage skills: a structural equation modelling analysis. BMC Nurs. Feb 21, 2022;21(1):46. [CrossRef] [Medline]33,Husna C, Kamil H, Yahya M, Tahlil T, Darmawati D. Does tabletop exercise enhance knowledge and attitude in preparing disaster drills? Nurs Med J Nursing. Aug 27, 2020;10(2):182-190. [CrossRef]37]. The promotion of gamified teaching in disaster nursing education is widely accepted and recognized.

However, considerable variation exists in assessment results concerning the long-term effects of gamified instruction, which may arise from several factors. First, differences in intervention duration can influence knowledge retention. For instance, a 5-week instructional intervention that developed an app and incorporated various gamification elements, such as collaboration, storytelling, and competition, resulted in relatively stable knowledge retention 1 month postintervention [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31]. In contrast, a study using a brief 2-hour educational game demonstrated a significant decline in knowledge retention 1 month after the intervention [Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36]. Second, the richness of gamification elements was strongly correlated with knowledge retention outcomes. A singular game model (eg, relying solely on contextual narratives) may diminish long-term effects [Mirzaei S, Eftekhari A, Mohammadinia L, Dehghani Tafti AA, Norouzinia R, Nasiriani K. Comparison of the effect of lecturing and tabletop exercise methods on level of preparedness of nurses against natural disasters. J Holist Nurs Midwifery. 2020;30:17-26. [CrossRef]36], whereas an instructional design that integrates multidimensional game mechanisms (eg, resource management, time pressure, and immediate feedback) is more conducive to long-term knowledge stabilization [Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]31]. Third, the construction of learning scenarios also impacts knowledge retention. Research indicates that self-directed learning models lacking instructor guidance and external situational support, which primarily depend on stand-alone mobile software, experienced a sustained decline in knowledge retention after 6 weeks [Calik A, Cakmak B, Kapucu S, Inkaya B. The effectiveness of serious games designed for infection prevention and promotion of safe behaviors of senior nursing students during the COVID-19 pandemic. Am J Infect Control. Dec 2022;50(12):1360-1367. [CrossRef] [Medline]32], underscoring the importance of creating an external learning environment to maintain learning outcomes. Additionally, the heterogeneity of study populations, variations in the reliability of assessment tools, and the diversity of gamified instructional formats (eg, apps, physical games, virtual reality, etc) may further restrict the comparability of results across studies.

Future Research

Through a systematic review of existing studies, we identified several limitations in the application of gamification methods in disaster nursing education, despite their noted successes. First, regarding research design, the majority of studies used quasi-experimental frameworks, lacking robust evidence from RCTs, and many had small sample sizes, potentially compromising the validity of their findings. Furthermore, significant variability in the implementation of gamified instruction, assessment tools, and training durations across studies has resulted in limited comparability of outcomes [Thomas D. A New Culture of Learning: Cultivating the Imagination for A World of Constant Change. CreateSpace Independent Publishing Platform; 2011:137. URL: https:/​/www.​researchgate.net/​publication/​303960672_A_New_Culture_of_Learning_Cultivating_the_Imagination_for_a_World_of_Constant_Change [Accessed 2011-03-01] 48]. Second, the impact of cultural and educational backgrounds on the effectiveness of gamification warrants consideration. For instance, pedagogical approaches that prove effective in technologically advanced virtual reality settings may not translate well to resource-limited environments [Yao J, Song D, Xiao T, Zhao J. Smartwatch-based tailored gamification and user modeling for motivating physical exercise: experimental study with the maximum difference scaling segmentation method. JMIR Serious Games. Apr 18, 2025;13:e66793. [CrossRef] [Medline]43]. Third, the existing literature has not evaluated cost-effectiveness, hindering the ability to ascertain the relationship between costs and benefits. Finally, while gamified instruction is typically conducted in simulated environments, existing studies have not assessed its clinical performance in real-life disaster scenarios, which are characterized by unique tensions, stresses, and complexities, as well as various uncontrollable factors that may influence performance in disaster care.

In summary, to enhance the scientific and practical value of disaster nursing education research, future studies should focus on optimizing the following aspects: First, it is recommended to establish a standardized assessment framework, uniformly adopting indicators such as knowledge retention rates and mastery of practical skills, along with measurement tools such as the Structured Clinical Assessment Scale. Longitudinal assessments should be conducted at predefined intervals (eg, 1 month and 3 months postintervention) to improve result comparability. Additionally, adaptive gamified instructional programs should be designed based on local cultural contexts and technological resources. Second, research design should prioritize multicenter RCTs and increase sample sizes to enhance external validity. The synergistic effects of gamified teaching and other methods (eg, situational simulation and didactic approaches) should also be explored to construct a diversified educational framework that considers efficiency and population characteristics. Furthermore, studies should examine the differences between gamified teaching and actual clinical performance, particularly in real disaster scenarios, while remaining vigilant to the risks of overimmersion and distraction in virtual environments. Finally, most existing studies focus on short-term effect assessments; while lightweight game elements (eg, points and badges) may motivate participants in the short term, they often fail to promote long-term memory integration due to a lack of in-depth narratives and contextual coherence. Therefore, future studies should further validate the long-term effects of various training modalities.

Limitations

This study adhered rigorously to the PRISMA framework to ensure methodological integrity. However, several limitations were identified. First, the quality of the original studies was constrained, with 68.75% (11/16) of the included studies exhibiting a high risk of bias. Key issues included the absence of control groups, unvalidated assessment tools, and a singular focus on outcome measures. Second, literature inclusion was biased. Due to the research team’s language proficiency limitations, only Chinese and English literature was considered, excluding gray literature and potentially omitting significant evidence from non–English-speaking regions. Third, the reliability of measurement instruments was questionable, as some studies failed to explicitly detail the tools used for knowledge assessment and their reliability and validity, precluding assumptions of high reliability for the outcome measures. Fourth, sample representativeness was limited; to ensure population homogeneity, studies with mixed health care workforces were excluded, which may diminish the applicability of findings to interprofessional teams. Fifth, there exists a risk of extrapolating findings, as existing evidence predominantly originates from Asian countries, and the empirical application of gamified teaching in disaster care remains nascent, thereby constraining the generalizability of results. Notably, while the stringent inclusion criteria for quasi-experimental and experimental studies enhance the level of evidence, they also reduce the analyzable sample size. Future research should broaden methodological inclusiveness to strengthen the relevant evidence.

Conclusions

By systematically integrating multidimensional evidence and proposing a classification framework for the first time, this study addresses a significant gap in the field, which has lacked a comprehensive evaluation of effectiveness, and provides clear guidance to educators regarding the selection of gamification tools (eg, virtual reality for simulating high-stakes scenarios and tabletop gaming for resource-constrained environments).

Overall, the systematic review indicates that gamified teaching holds substantial value for both nursing students and registered nurses, enhancing not only disaster care knowledge but also practical skills (eg, triage, evacuation decision-making, and infectious disease management). However, the successful implementation of gamified instruction hinges on the careful selection of target learners, learning content, and suitable gamified elements. Furthermore, future research should explore a hybrid teaching model and develop a unified system of assessment indicators (eg, standardized OSCE scales and long-term follow-up protocols) to mitigate interstudy heterogeneity, enhance result comparability, and facilitate the broader application of gamified teaching in disaster nursing education.

Authors' Contributions

SB was the principal investigator. SB was involved in conceptualization, study design, data collection, data curation, formal analysis, writing the original draft, and editing the revised draft. HZ was involved in conceptualization, data collection, review, and editing. QZ was involved in the conceptualization and participated in discussions of study selection when the first 2 authors had conflicting opinions. LC guided conceptualization and data. MH was involved in conceptualization, methodological guidance, data validation, formal analysis, writing review and editing, and supervision.

Conflicts of Interest

None declared.

Multimedia Appendix 1

Search strategy.

DOCX File, 22 KB

Checklist 1

PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) checklist.

PDF File, 87 KB

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  31. Masoumian H, Hosseini TM, Qayumi K, et al. Game-based vs. case-based training for increasing knowledge and behavioral fluency of nurse students regarding crisis and disaster management; a quasi-experimental study. Arch Acad Emerg Med. Sep 24, 2022;10(1):e77. [CrossRef]
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OSCE: Objective Structured Clinical Examination
PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses
RCT: randomized controlled trial


Edited by Javad Sarvestan; submitted 25.03.25; peer-reviewed by Jeffrey Wong, Reenu Singh, Timothy Ojo; final revised version received 27.04.25; accepted 29.04.25; published 09.07.25.

Copyright

© Shiyi Bai, HuiJuan Zeng, Qianmei Zhong, Lulu Cao, Mei He. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 9.7.2025.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.