An Easy and Quick Risk-Stratified Early Forewarning Model for Septic Shock in the Intensive Care Unit: Development, Validation, and Interpretation Study

Guanghao Liu   ^{1, 2, 3 *} , PhD ;   Shixiang Zheng   ^{2, 4 *} , MD, PhD ;   Jun He   ^{1, 2, 5 *} , PhD ;   Zi-Mei Zhang   ⁶ , PhD ;   Ruoqiong Wu   ^{1, 2} , MSc ;   Yingying Yu   ^{1, 2} , MSc ;   Hao Fu   ^{1, 2} , MSc ;   Li Han   ^{1, 2} , MSc ;   Haibo Zhu   ^{1, 2, 3} , PhD ;   Yichang Xu   ^{1, 2, 7} , MSc ;   Huaguo Shao   ^{1, 2} , MSc ;   Haidan Yan   ^{1, 2, 5} , PhD ;   Ting Chen   ^{1, 2, 8} , PhD ;   Xiaopei Shen   ^{1, 2, 3, 5} , PhD

¹ Department of Bioinformatics, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China

² Fujian Key Laboratory of Medical Bioinformatics, Institute of Precision Medicine, Fujian Medical University, Fuzhou, China

³ School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China

⁴ Department of Critical Care Medicine, Union Hospital of Fujian Medical University, Fuzhou, China

⁵ Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China

⁶ School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China

⁷ School of Medical Imaging, Fujian Medical University, Fuzhou, China

⁸ Department of Computer Science and Technology, Institute of Artificial Intelligence,  Beijing National Research Center for Information Science and Technology, Tsinghua University, Beijing, China

*these authors contributed equally