Establishing Medical Intelligence—Leveraging Fast Healthcare Interoperability Resources to Improve Clinical Management: Retrospective Cohort and Clinical Implementation Study

Alexander Brehmer   ^{1 *} , MSc ;   Christopher Martin Sauer   ^{1, 2 *} , MD, MPH, PhD ;   Jayson Salazar Rodríguez   ^{1 *} , MSc ;   Kelsey Herrmann   ¹ , MD ;   Moon Kim   ¹ , MD ;   Julius Keyl   ^{1, 3} , MD ;   Fin Hendrik Bahnsen   ¹ , MSc ;   Benedikt Frank   ⁴ , MD ;   Martin Köhrmann   ⁴ , MD ;   Tienush Rassaf   ⁵ , MD ;   Amir-Abbas Mahabadi   ⁵ , MD ;   Boris Hadaschik   ⁶ , MD ;   Christopher Darr   ⁶ , MD ;   Ken Herrmann   ⁷ , MD ;   Susanne Tan   ⁸ , Prof Dr Med ;   Jan Buer   ⁹ , Prof Dr Med ;   Thorsten Brenner   ¹⁰ , MD ;   Hans Christian Reinhardt   ² , Prof Dr Med ;   Felix Nensa   ¹ , PhD, Prof Dr Med ;   Michael Gertz   ¹¹ , Dr rer nat ;   Jan Egger   ¹ , PhD ;   Jens Kleesiek   ¹ , PhD, Prof Dr Med

¹ Institute for Artificial Intelligence in Medicine, University Hospital Essen, Essen, Germany

² Deptartment of Hematology and Stem Cell Transplantation, West German Cancer Center, German Cancer Consortium Partner Site Essen, Center for Molecular Biotechnology, University Hospital Essen, Essen, Germany

³ Institute of Pathology, University Hospital Essen, Essen, Germany

⁴ Department of Neurology, University Hospital Essen, Essen, Germany

⁵ Department of Cardiology and Vascular Medicine, West German Heart- and Vascular Center, University Hospital Essen, Essen, Germany

⁶ Department of Urology and German Cancer Consortium (DKTK) Partner Site, University Hospital Essen, Essen, Germany

⁷ Department of Radiotherapy, University Hospital Essen, Essen, Germany

⁸ Department of Endocrinology, Diabetes and Metabolism, University Hospital Essen, Essen, Germany

⁹ Institute of Medical Microbiology, University Hospital Essen, Essen, Germany

¹⁰ Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, Essen, Germany

¹¹ Institute of Computer Science, Heidelberg University, Heidelberg, Germany

*these authors contributed equally