Association of Remote Patient-Reported Outcomes and Step Counts With Hospitalization or Death Among Patients With Advanced Cancer Undergoing Chemotherapy: Secondary Analysis of the PROStep Randomized Trial

Christopher R Manz   ¹ , MSHP, MD ;   Emily Schriver   ^{2, 3} , MS ;   William J Ferrell   ^{4, 5} , MPH ;   Joelle Williamson   ⁶ , MPH ;   Jonathan Wakim   ⁶ , BS ;   Neda Khan   ^{6, 7} , MHCI ;   Michael Kopinsky   ⁷ , BSE ;   Mohan Balachandran   ⁷ , MA, MS ;   Jinbo Chen   ^{5, 8} , PhD ;   Mitesh S Patel   ⁹ , MBA, MD ;   Samuel U Takvorian   ^{5, 6, 10} , MSHP, MD ;   Lawrence N Shulman   ^{5, 6, 10} , MD ;   Justin E Bekelman   ^{5, 10} , MD ;   Ian J Barnett   ^{8 *} , PhD ;   Ravi B Parikh   ^{2, 4, 5, 10, 11 *} , MPP, MD

¹ Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States

² Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA, United States

³ Penn Medicine Predictive Healthcare, University of Pennsylvania Health System, Philadelphia, PA, United States

⁴ Division of Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

⁵ Penn Center for Cancer Care Innovation, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, United States

⁶ Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

⁷ Center for Health Care Innovation, Penn Medicine, Philadelphia, PA, United States

⁸ Department of Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

⁹ Ascension, St. Louis, MO, United States

¹⁰ Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, United States

¹¹ Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States

*these authors contributed equally