Generate Analysis-Ready Data for Real-world Evidence: Tutorial for Harnessing Electronic Health Records With Advanced Informatic Technologies

Jue Hou   ¹ , PhD ;   Rachel Zhao   ² , BSc ;   Jessica Gronsbell   ³ , PhD ;   Yucong Lin   ⁴ , PhD ;   Clara-Lea Bonzel   ⁵ , MSc ;   Qingyi Zeng   ¹ , BSc ;   Sinian Zhang   ⁶ ;   Brett K Beaulieu-Jones   ⁷ , PhD ;   Griffin M Weber   ⁵ , MD, PhD ;   Thomas Jemielita   ⁸ , PhD ;   Shuyan Sabrina Wan   ⁸ , PhD ;   Chuan Hong   ⁹ , PhD ;   Tianrun Cai   ⁵ , MD, PhD ;   Jun Wen   ⁵ , PhD ;   Vidul Ayakulangara Panickan   ⁵ , MSc ;   Kai-Li Liaw   ⁸ , PhD ;   Katherine Liao   ^{5, 10} , MPH, MD ;   Tianxi Cai   ^{5, 11} , ScD

¹ Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States

² Department of Medicine, University of British Columbia, Vancouver, BC, Canada

³ Department of Statistical Sciences, University of Toronto, Toronto, ON, Canada

⁴ Institute of Engineering Medicine, Beijing Institute of Technology, Beijing, China

⁵ Department of Biomedical Informatics, Harvard Medical School, Boston, MA, United States

⁶ School of Statistics, Renmin University of China, Bejing, China

⁷ Department of Medicine, University of Chicago, Chicago, IL, United States

⁸ Merck & Co, Inc, Rahway, NJ, United States

⁹ Department of Biostatistics & Bioinformatics, Duke University, Durham, NC, United States

¹⁰ Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States

¹¹ Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, United States