An Automatically Adaptive Digital Health Intervention to Decrease Opioid-Related Risk While Conserving Counselor Time: Quantitative Analysis of Treatment Decisions Based on Artificial Intelligence and Patient-Reported Risk Measures

John D Piette   ^{1, 2} , MSc, PhD ;   Laura Thomas   ^{1, 3} , MPH, LMSW ;   Sean Newman   ^{1, 2} , MS ;   Nicolle Marinec   ^{1, 2} , MPH ;   Joel Krauss   ⁴ , MD ;   Jenny Chen   ^{1, 2} , MPH ;   Zhenke Wu   ⁵ , PhD ;   Amy S B Bohnert   ^{1, 3} , PhD

¹ Ann Arbor Department of Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, United States

² Department of Health Behavior Health Education, School of Public Health, University of Michigan, Ann Arbor, MI, United States

³ Department of Anesthesiology, School of Medicine, University of Michigan, Ann Arbor, MI, United States

⁴ Department of Emergency Medicine, Trinity Health St. Joseph Mercy, Ann Arbor, MI, United States

⁵ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, United States