Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational Randomized Controlled Trial

Nicola Coley   ^{1, 2} , PhD ;   Laurine Andre   ¹ , MD ;   Marieke P Hoevenaar-Blom   ^{3, 4, 5} , PhD ;   Tiia Ngandu   ^{6, 7} , MD, PhD ;   Cathrien Beishuizen   ⁸ , MD, PhD ;   Mariagnese Barbera   ^{9, 10} , PhD ;   Lennard van Wanrooij   ⁴ , PhD ;   Miia Kivipelto   ^{7, 9, 10, 11} , MD, PhD ;   Hilkka Soininen   ^{9, 12} , MD, PhD ;   Willem van Gool   ⁵ , MD, PhD ;   Carol Brayne   ¹³ , MD ;   Eric Moll van Charante   ^{5, 8} , MD, PhD ;   Edo Richard   ^{3, 5} , MD, PhD ;   Sandrine Andrieu   ^{1, 2} , MD, PhD ;   HATICE study group   ¹⁴ ;   PRODEMOS study group   ¹⁴

¹ Center for Epidemiology and Research in Population health (CERPOP), University of Toulouse III Paul Sabatier (UPS), National Institute of Health and Medical Research (INSERM) mixed research unit (UMR) 1295, Toulouse, France

² Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France

³ Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, Netherlands

⁴ Department of Neurology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands

⁵ Department of Public and Occupational Health, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands

⁶ Population Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland

⁷ Division of Clinical Geriatrics, Center for Alzheimer Research, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden

⁸ Department of General Practice, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands

⁹ Institute of Clinical Medicine, Department of Neurology, University of Eastern Finland, Kuopio, Finland

¹⁰ Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, London, United Kingdom

¹¹ Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland

¹² Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland

¹³ Cambridge Public Health, University of Cambridge, Cambridge, United Kingdom

¹⁴ See Acknowledgements, o., Afghanistan