Published on in Vol 24, No 12 (2022): December

This is a member publication of University of Dundee (Jisc)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/40035, first published .
A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

Authors of this article:

Emily Jefferson 1 Author Orcid Image ;   Christian Cole 1 Author Orcid Image ;   Shahzad Mumtaz 1 Author Orcid Image ;   Samuel Cox 2 Author Orcid Image ;   Thomas Charles Giles 2 Author Orcid Image ;   Sam Adejumo 2 Author Orcid Image ;   Esmond Urwin 2 Author Orcid Image ;   Daniel Lea 2 Author Orcid Image ;   Calum Macdonald 3 Author Orcid Image ;   Joseph Best 2, 4 Author Orcid Image ;   Erum Masood 1 Author Orcid Image ;   Gordon Milligan 1 Author Orcid Image ;   Jenny Johnston 1 Author Orcid Image ;   Scott Horban 1 Author Orcid Image ;   Ipek Birced 1 Author Orcid Image ;   Christopher Hall 1 Author Orcid Image ;   Aaron S Jackson 1 Author Orcid Image ;   Clare Collins 2 Author Orcid Image ;   Sam Rising 2 Author Orcid Image ;   Charlotte Dodsley 2 Author Orcid Image ;   Jill Hampton 1 Author Orcid Image ;   Andrew Hadfield 2 Author Orcid Image ;   Roberto Santos 2 Author Orcid Image ;   Simon Tarr 2 Author Orcid Image ;   Vasiliki Panagi 2 Author Orcid Image ;   Joseph Lavagna 2 Author Orcid Image ;   Tracy Jackson 3 Author Orcid Image ;   Antony Chuter 5 Author Orcid Image ;   Jillian Beggs 1 Author Orcid Image ;   Magdalena Martinez-Queipo 6 Author Orcid Image ;   Helen Ward 7 Author Orcid Image ;   Julie von Ziegenweidt 8, 9 Author Orcid Image ;   Frances Burns 10 Author Orcid Image ;   Joanne Martin 11 Author Orcid Image ;   Neil Sebire 12 Author Orcid Image ;   Carole Morris 13 Author Orcid Image ;   Declan Bradley 14, 15 Author Orcid Image ;   Rob Baxter 16 Author Orcid Image ;   Anni Ahonen-Bishopp 17 Author Orcid Image ;   Paul Smith 17 Author Orcid Image ;   Amelia Shoemark 18 Author Orcid Image ;   Ana M Valdes 19 Author Orcid Image ;   Benjamin Ollivere 19 Author Orcid Image ;   Charlotte Manisty 20 Author Orcid Image ;   David Eyre 21 Author Orcid Image ;   Stephanie Gallant 18 Author Orcid Image ;   George Joy 22 Author Orcid Image ;   Andrew McAuley 23 Author Orcid Image ;   David Connell 24 Author Orcid Image ;   Kate Northstone 25 Author Orcid Image ;   Katie Jeffery 26, 27 Author Orcid Image ;   Emanuele Di Angelantonio 28, 29, 30, 31, 32 Author Orcid Image ;   Amy McMahon 28, 29 Author Orcid Image ;   Mat Walker 28, 29 Author Orcid Image ;   Malcolm Gracie Semple 33, 34 Author Orcid Image ;   Jessica Mai Sims 35 Author Orcid Image ;   Emma Lawrence 36 Author Orcid Image ;   Bethan Davies 7 Author Orcid Image ;   John Kenneth Baillie 37 Author Orcid Image ;   Ming Tang 38 Author Orcid Image ;   Gary Leeming 39 Author Orcid Image ;   Linda Power 40 Author Orcid Image ;   Thomas Breeze 41 Author Orcid Image ;   Duncan Murray 42, 43 Author Orcid Image ;   Chris Orton 44 Author Orcid Image ;   Iain Pierce 45, 46 Author Orcid Image ;   Ian Hall 47 Author Orcid Image ;   Shamez Ladhani 48 Author Orcid Image ;   Natalie Gillson 49 Author Orcid Image ;   Matthew Whitaker 7 Author Orcid Image ;   Laura Shallcross 50 Author Orcid Image ;   David Seymour 4 Author Orcid Image ;   Susheel Varma 4 Author Orcid Image ;   Gerry Reilly 4 Author Orcid Image ;   Andrew Morris 4 Author Orcid Image ;   Susan Hopkins 40 Author Orcid Image ;   Aziz Sheikh 51 Author Orcid Image ;   Philip Quinlan 2, 19 Author Orcid Image

Emily Jefferson   1 , BSc, PhD ;   Christian Cole   1 , BSc, PhD ;   Shahzad Mumtaz   1 , BSc, MCS, PhD ;   Samuel Cox   2 , MMath, PhD ;   Thomas Charles Giles   2 , BSc, PhD ;   Sam Adejumo   2 , MSc ;   Esmond Urwin   2 , BEng, MSc, PhD ;   Daniel Lea   2 , BSc, MSc ;   Calum Macdonald   3 , BSc, MPhys, PhD ;   Joseph Best   2, 4 ;   Erum Masood   1 , BE, MSc ;   Gordon Milligan   1 , BSc, MSc ;   Jenny Johnston   1 ;   Scott Horban   1 , BSc ;   Ipek Birced   1 , BSc, BA, MSc ;   Christopher Hall   1 , BSc ;   Aaron S Jackson   1 , BSc, PhD ;   Clare Collins   2 , BA ;   Sam Rising   2 , BSc ;   Charlotte Dodsley   2 ;   Jill Hampton   1 , BA ;   Andrew Hadfield   2 , BSc ;   Roberto Santos   2 , PhD ;   Simon Tarr   2 , PhD ;   Vasiliki Panagi   2 , BSc, MSc ;   Joseph Lavagna   2 , BSc, MSc ;   Tracy Jackson   3 , BA, MSc, PhD ;   Antony Chuter   5 ;   Jillian Beggs   1 , BSc ;   Magdalena Martinez-Queipo   6 , DipNur, RN, BSc, MClinRes ;   Helen Ward   7 , PhD ;   Julie von Ziegenweidt   8, 9 ;   Frances Burns   10 , BA, PhD ;   Joanne Martin   11 , BS, MA, MB, PhD ;   Neil Sebire   12 , MBBS, BClinSci, MD ;   Carole Morris   13 , BSc ;   Declan Bradley   14, 15 , PhD ;   Rob Baxter   16 , BSc, MSc, PhD ;   Anni Ahonen-Bishopp   17 , PhD ;   Paul Smith   17 , BSc, MBA ;   Amelia Shoemark   18 , BSc, ClinSci, PhD ;   Ana M Valdes   19 , PhD ;   Benjamin Ollivere   19 , MBBS, MA, MD ;   Charlotte Manisty   20 , MBBS, MA, PhD ;   David Eyre   21 , BM, BCh, DPhil ;   Stephanie Gallant   18 , BN, MA, MSc ;   George Joy   22 , MBBS ;   Andrew McAuley   23 , BA, MSc, PhD ;   David Connell   24 , BM BCh, MA, PhD ;   Kate Northstone   25 , BSc, MSc, PhD ;   Katie Jeffery   26, 27 , BCh, BM, MA, PhD ;   Emanuele Di Angelantonio   28, 29, 30, 31, 32 , MSc, MD, PhD ;   Amy McMahon   28, 29 , BSc, PhD ;   Mat Walker   28, 29 , BSc, PhD ;   Malcolm Gracie Semple   33, 34 , BSc, BM, BCh, PhD ;   Jessica Mai Sims   35 , BA, MSc ;   Emma Lawrence   36 , BSc, PhD ;   Bethan Davies   7 , MB, BChir, MPH, PhD ;   John Kenneth Baillie   37 , BSc, MBChB, PhD ;   Ming Tang   38 , BSc, MBA ;   Gary Leeming   39 , BA ;   Linda Power   40 ;   Thomas Breeze   41 , BA (Hon), PGCE, MSc ;   Duncan Murray   42, 43 , BM, BCh, MA, PhD ;   Chris Orton   44 , BA, MSc ;   Iain Pierce   45, 46 , BSc, MSc, PhD ;   Ian Hall   47 , BA, BM, BCh, DM ;   Shamez Ladhani   48 , PhD ;   Natalie Gillson   49 , BSc ;   Matthew Whitaker   7 , BA, MSc ;   Laura Shallcross   50 , BA, MBBS, MSc, PhD ;   David Seymour   4 , BSc ;   Susheel Varma   4 , BEng, MSc, MBA, PhD ;   Gerry Reilly   4 , BSc, MSc ;   Andrew Morris   4 , MD, PhD ;   Susan Hopkins   40 , BA, MB, MSc, MD ;   Aziz Sheikh   51 , BSc, MBBS, MSc, MD ;   Philip Quinlan   2, 19 , BSc, PhD

1 Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

2 Digital Research Service, University of Nottingham, Nottingham, United Kingdom

3 Usher Institute, University of Edinburgh, Edinburgh, United Kingdom

4 Health Data Research UK, London, United Kingdom

5 Lay Partnership in Healthcare Research, Lindfield, United Kingdom

6 National Health Service Digital, London, United Kingdom

7 School of Public Health, Imperial College London, London, United Kingdom

8 Department of Haemotology, University of Cambridge, Cambridge, United Kingdom

9 National Institute for Healthcare Research BioResource, Cambridge University Hospitals NHS Foundation, Cambridge Biomedical Campus, Cambridge, United Kingdom

10 Centre for Public Health, Belfast Institute of Clinical Science, Queens University Belfast, Belfast, United Kingdom

11 Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

12 Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom

13 Public Health Scotland, Edinburgh, United Kingdom

14 Centre for Public Health, Institute of Clinical Science, Queen's University Belfast, Belfast, United Kingdom

15 Public Health Agency, Belfast, United Kingdom

16 EPCC, University of Edinburgh, Edinburgh, United Kingdom

17 BC Platforms, Espoo, Finland

18 Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom

19 School of Medicine, University of Nottingham, Nottingham, United Kingdom

20 Institute of Cardiovascular Sciences, University of College London, London, United Kingdom

21 Big Data Institute, University of Oxford, Oxford, United Kingdom

22 Barts Heart Centre, London, United Kingdom

23 Clinical and Protecting Health Directorate, Public Health Scotland, Glasgow, United Kingdom

24 School of Medicine, University of Dundee, Dundee, United Kingdom

25 Population Health Sciences, Avon Longitudinal Study of Parents and Children, Bristol, United Kingdom

26 Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom

27 Radcliffe Department of Medicine, Oxford University, Oxford, United Kingdom

28 British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

29 National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, United Kingdom

30 Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, United Kingdom

31 Health Data Science Research Centre, Human Technopole, Milan, Italy

32 British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom

33 Respiratory Department, Alder Hey Children's Hospital, Liverpool, United Kingdom

34 Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infections, University of Liverpool, Liverpool, United Kingdom

35 University College London, London, United Kingdom

36 BioIndustry Association, London, United Kingdom

37 Outbreak Data Analysis Platform, University of Edinburgh, Edinburgh, United Kingdom

38 NHS England, Worcestershire, United Kingdom

39 Civic Data Cooperative, Digital Innovation Facility, University of Liverpool, Liverpool, United Kingdom

40 Public Health England, London, United Kingdom

41 Avon Longitudinal Study of Parents and Children, Bristol Medical School, University of Bristol, Bristol, United Kingdom

42 University Hospital Coventry & Warwickshire NHS Trust, Coventry, United Kingdom

43 University of Birmingham, Birmingham, United Kingdom

44 Population Data Science, Swansea University Medical School, Swansea, United Kingdom

45 Institute of Cardiovascular Science, University College London, London, United Kingdom

46 Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom

47 Nottingham Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom

48 Immunisation and Countermeasures Division, Public Health England Colindale, London, United Kingdom

49 UK Health Security Agency, London, United Kingdom

50 Institute of Health Informatics, UCL, London, United Kingdom

51 Centre for Population Health Sciences, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom

Corresponding Author:

  • Emily Jefferson, BSc, PhD
  • Health Informatics Centre
  • Division of Population and Health Genomics
  • School of Medicine, University of Dundee
  • Ninewells Hospital
  • Dundee, DD1 9SY
  • United Kingdom
  • Phone: 44 01382 383 353
  • Email: e.r.jefferson@dundee.ac.uk