Published on in Vol 24, No 12 (2022): December

This is a member publication of University of Dundee (Jisc)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/40035, first published .
A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

A Hybrid Architecture (CO-CONNECT) to Facilitate Rapid Discovery and Access to Data Across the United Kingdom in Response to the COVID-19 Pandemic: Development Study

Authors of this article:

Emily Jefferson1 Author Orcid Image ;   Christian Cole1 Author Orcid Image ;   Shahzad Mumtaz1 Author Orcid Image ;   Samuel Cox2 Author Orcid Image ;   Thomas Charles Giles2 Author Orcid Image ;   Sam Adejumo2 Author Orcid Image ;   Esmond Urwin2 Author Orcid Image ;   Daniel Lea2 Author Orcid Image ;   Calum Macdonald3 Author Orcid Image ;   Joseph Best2, 4 Author Orcid Image ;   Erum Masood1 Author Orcid Image ;   Gordon Milligan1 Author Orcid Image ;   Jenny Johnston1 Author Orcid Image ;   Scott Horban1 Author Orcid Image ;   Ipek Birced1 Author Orcid Image ;   Christopher Hall1 Author Orcid Image ;   Aaron S Jackson1 Author Orcid Image ;   Clare Collins2 Author Orcid Image ;   Sam Rising2 Author Orcid Image ;   Charlotte Dodsley2 Author Orcid Image ;   Jill Hampton1 Author Orcid Image ;   Andrew Hadfield2 Author Orcid Image ;   Roberto Santos2 Author Orcid Image ;   Simon Tarr2 Author Orcid Image ;   Vasiliki Panagi2 Author Orcid Image ;   Joseph Lavagna2 Author Orcid Image ;   Tracy Jackson3 Author Orcid Image ;   Antony Chuter5 Author Orcid Image ;   Jillian Beggs1 Author Orcid Image ;   Magdalena Martinez-Queipo6 Author Orcid Image ;   Helen Ward7 Author Orcid Image ;   Julie von Ziegenweidt8, 9 Author Orcid Image ;   Frances Burns10 Author Orcid Image ;   Joanne Martin11 Author Orcid Image ;   Neil Sebire12 Author Orcid Image ;   Carole Morris13 Author Orcid Image ;   Declan Bradley14, 15 Author Orcid Image ;   Rob Baxter16 Author Orcid Image ;   Anni Ahonen-Bishopp17 Author Orcid Image ;   Paul Smith17 Author Orcid Image ;   Amelia Shoemark18 Author Orcid Image ;   Ana M Valdes19 Author Orcid Image ;   Benjamin Ollivere19 Author Orcid Image ;   Charlotte Manisty20 Author Orcid Image ;   David Eyre21 Author Orcid Image ;   Stephanie Gallant18 Author Orcid Image ;   George Joy22 Author Orcid Image ;   Andrew McAuley23 Author Orcid Image ;   David Connell24 Author Orcid Image ;   Kate Northstone25 Author Orcid Image ;   Katie Jeffery26, 27 Author Orcid Image ;   Emanuele Di Angelantonio28, 29, 30, 31, 32 Author Orcid Image ;   Amy McMahon28, 30 Author Orcid Image ;   Mat Walker28, 30 Author Orcid Image ;   Malcolm Gracie Semple33, 34 Author Orcid Image ;   Jessica Mai Sims35 Author Orcid Image ;   Emma Lawrence36 Author Orcid Image ;   Bethan Davies7 Author Orcid Image ;   John Kenneth Baillie37 Author Orcid Image ;   Ming Tang38 Author Orcid Image ;   Gary Leeming39 Author Orcid Image ;   Linda Power40 Author Orcid Image ;   Thomas Breeze41 Author Orcid Image ;   Duncan Murray42, 43 Author Orcid Image ;   Chris Orton44 Author Orcid Image ;   Iain Pierce45, 46 Author Orcid Image ;   Ian Hall47 Author Orcid Image ;   Shamez Ladhani48 Author Orcid Image ;   Natalie Gillson49 Author Orcid Image ;   Matthew Whitaker7 Author Orcid Image ;   Laura Shallcross50 Author Orcid Image ;   David Seymour4 Author Orcid Image ;   Susheel Varma4 Author Orcid Image ;   Gerry Reilly4 Author Orcid Image ;   Andrew Morris4 Author Orcid Image ;   Susan Hopkins40 Author Orcid Image ;   Aziz Sheikh51 Author Orcid Image ;   Philip Quinlan2, 19 Author Orcid Image

Emily Jefferson   1 , BSc, PhD ;   Christian Cole   1 , BSc, PhD ;   Shahzad Mumtaz   1 , BSc, MCS, PhD ;   Samuel Cox   2 , MMath, PhD ;   Thomas Charles Giles   2 , BSc, PhD ;   Sam Adejumo   2 , MSc ;   Esmond Urwin   2 , BEng, MSc, PhD ;   Daniel Lea   2 , BSc, MSc ;   Calum Macdonald   3 , BSc, MPhys, PhD ;   Joseph Best   2, 4 ;   Erum Masood   1 , BE, MSc ;   Gordon Milligan   1 , BSc, MSc ;   Jenny Johnston   1 ;   Scott Horban   1 , BSc ;   Ipek Birced   1 , BSc, BA, MSc ;   Christopher Hall   1 , BSc ;   Aaron S Jackson   1 , BSc, PhD ;   Clare Collins   2 , BA ;   Sam Rising   2 , BSc ;   Charlotte Dodsley   2 ;   Jill Hampton   1 , BA ;   Andrew Hadfield   2 , BSc ;   Roberto Santos   2 , PhD ;   Simon Tarr   2 , PhD ;   Vasiliki Panagi   2 , BSc, MSc ;   Joseph Lavagna   2 , BSc, MSc ;   Tracy Jackson   3 , BA, MSc, PhD ;   Antony Chuter   5 ;   Jillian Beggs   1 , BSc ;   Magdalena Martinez-Queipo   6 , DipNur, RN, BSc, MClinRes ;   Helen Ward   7 , PhD ;   Julie von Ziegenweidt   8, 9 ;   Frances Burns   10 , BA, PhD ;   Joanne Martin   11 , BS, MA, MB, PhD ;   Neil Sebire   12 , MBBS, BClinSci, MD ;   Carole Morris   13 , BSc ;   Declan Bradley   14, 15 , PhD ;   Rob Baxter   16 , BSc, MSc, PhD ;   Anni Ahonen-Bishopp   17 , PhD ;   Paul Smith   17 , BSc, MBA ;   Amelia Shoemark   18 , BSc, ClinSci, PhD ;   Ana M Valdes   19 , PhD ;   Benjamin Ollivere   19 , MBBS, MA, MD ;   Charlotte Manisty   20 , MBBS, MA, PhD ;   David Eyre   21 , BM, BCh, DPhil ;   Stephanie Gallant   18 , BN, MA, MSc ;   George Joy   22 , MBBS ;   Andrew McAuley   23 , BA, MSc, PhD ;   David Connell   24 , BM BCh, MA, PhD ;   Kate Northstone   25 , BSc, MSc, PhD ;   Katie Jeffery   26, 27 , BCh, BM, MA, PhD ;   Emanuele Di Angelantonio   28, 29, 30, 31, 32 , MSc, MD, PhD ;   Amy McMahon   28, 30 , BSc, PhD ;   Mat Walker   28, 30 , BSc, PhD ;   Malcolm Gracie Semple   33, 34 , BSc, BM, BCh, PhD ;   Jessica Mai Sims   35 , BA, MSc ;   Emma Lawrence   36 , BSc, PhD ;   Bethan Davies   7 , MB, BChir, MPH, PhD ;   John Kenneth Baillie   37 , BSc, MBChB, PhD ;   Ming Tang   38 , BSc, MBA ;   Gary Leeming   39 , BA ;   Linda Power   40 ;   Thomas Breeze   41 , BA (Hon), PGCE, MSc ;   Duncan Murray   42, 43 , BM, BCh, MA, PhD ;   Chris Orton   44 , BA, MSc ;   Iain Pierce   45, 46 , BSc, MSc, PhD ;   Ian Hall   47 , BA, BM, BCh, DM ;   Shamez Ladhani   48 , PhD ;   Natalie Gillson   49 , BSc ;   Matthew Whitaker   7 , BA, MSc ;   Laura Shallcross   50 , BA, MBBS, MSc, PhD ;   David Seymour   4 , BSc ;   Susheel Varma   4 , BEng, MSc, MBA, PhD ;   Gerry Reilly   4 , BSc, MSc ;   Andrew Morris   4 , MD, PhD ;   Susan Hopkins   40 , BA, MB, MSc, MD ;   Aziz Sheikh   51 , BSc, MBBS, MSc, MD ;   Philip Quinlan   2, 19 , BSc, PhD

1 Health Informatics Centre, Division of Population and Health Genomics, School of Medicine, University of Dundee, Dundee, United Kingdom

2 Digital Research Service, University of Nottingham, Nottingham, United Kingdom

3 Usher Institute, University of Edinburgh, Edinburgh, United Kingdom

4 Health Data Research UK, London, United Kingdom

5 Lay Partnership in Healthcare Research, Lindfield, United Kingdom

6 National Health Service Digital, London, United Kingdom

7 School of Public Health, Imperial College London, London, United Kingdom

8 Department of Haemotology, University of Cambridge, Cambridge, United Kingdom

9 National Institute for Healthcare Research BioResource, Cambridge University Hospitals NHS Foundation, Cambridge Biomedical Campus, Cambridge, United Kingdom

10 Centre for Public Health, Belfast Institute of Clinical Science, Queens University Belfast, Belfast, United Kingdom

11 Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

12 Institute of Child Health, Great Ormond Street Hospital, London, United Kingdom

13 Public Health Scotland, Edinburgh, United Kingdom

14 Centre for Public Health, Institute of Clinical Science, Queen's University Belfast, Belfast, United Kingdom

15 Public Health Agency, Belfast, United Kingdom

16 EPCC, University of Edinburgh, Edinburgh, United Kingdom

17 BC Platforms, Espoo, Finland

18 Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom

19 School of Medicine, University of Nottingham, Nottingham, United Kingdom

20 Institute of Cardiovascular Sciences, University of College London, London, United Kingdom

21 Big Data Institute, University of Oxford, Oxford, United Kingdom

22 Barts Heart Centre, London, United Kingdom

23 Clinical and Protecting Health Directorate, Public Health Scotland, Glasgow, United Kingdom

24 School of Medicine, University of Dundee, Dundee, United Kingdom

25 Population Health Sciences, Avon Longitudinal Study of Parents and Children, Bristol, United Kingdom

26 Radcliffe Department of Medicine, Oxford University, Oxford, United Kingdom

27 Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom

28 British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

29 British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, United Kingdom

30 National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, United Kingdom

31 Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, United Kingdom

32 Health Data Science Research Centre, Human Technopole, Milan, Italy

33 Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infections, University of Liverpool, Liverpool, United Kingdom

34 Respiratory Department, Alder Hey Children's Hospital, Liverpool, United Kingdom

35 University College London, London, United Kingdom

36 BioIndustry Association, London, United Kingdom

37 Outbreak Data Analysis Platform, University of Edinburgh, Edinburgh, United Kingdom

38 NHS England, Worcestershire, United Kingdom

39 Civic Data Cooperative, Digital Innovation Facility, University of Liverpool, Liverpool, United Kingdom

40 Public Health England, London, United Kingdom

41 Avon Longitudinal Study of Parents and Children, Bristol Medical School, University of Bristol, Bristol, United Kingdom

42 University of Birmingham, Birmingham, United Kingdom

43 University Hospital Coventry & Warwickshire NHS Trust, Coventry, United Kingdom

44 Population Data Science, Swansea University Medical School, Swansea, United Kingdom

45 Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom

46 Institute of Cardiovascular Science, University College London, London, United Kingdom

47 Nottingham Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom

48 Immunisation and Countermeasures Division, Public Health England Colindale, London, United Kingdom

49 UK Health Security Agency, London, United Kingdom

50 Institute of Health Informatics, UCL, London, United Kingdom

51 Centre for Population Health Sciences, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom

Corresponding Author:

  • Emily Jefferson, BSc, PhD
  • Health Informatics Centre
  • Division of Population and Health Genomics
  • School of Medicine, University of Dundee
  • Ninewells Hospital
  • Dundee, DD1 9SY
  • United Kingdom
  • Phone: 44 01382 383 353
  • Email: e.r.jefferson@dundee.ac.uk