Effect of Cognitive Training in Fully Immersive Virtual Reality on Visuospatial Function and Frontal-Occipital Functional Connectivity in Predementia: Randomized Controlled Trial

Jae Myeong Kang   ^{1, 2} , MD ;   Nambeom Kim   ³ , PhD ;   Sook Young Lee   ¹ , BSc ;   Soo Kyun Woo   ¹ , MD ;   Geumjin Park   ¹ , MA ;   Byeong Kil Yeon   ⁴ , MD, PhD ;   Jung Woon Park   ⁵ , PhD ;   Jung-Hae Youn   ⁶ , PhD ;   Seung-Ho Ryu   ⁷ , MD, PhD ;   Jun-Young Lee   ⁸ , MD, PhD ;   Seong-Jin Cho   ¹ , MD, PhD

¹ Department of Psychiatry, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea

² Brain Health Center, Gil Medical Center, Incheon, Republic of Korea

³ Biomedical Engineering Research Center, Gachon University, Incheon, Republic of Korea

⁴ Department of Psychiatry, Gyeonggi Provincial Medical Center Suwon Hospital, Suwon, Republic of Korea

⁵ Department of Game Engineering and IT Convergence Engineering, Graduate School of Gachon University, Seongnam, Republic of Korea

⁶ Department of Counseling Psychology, Cha University, Seongnam, Republic of Korea

⁷ Department of Psychiatry, School of Medicine, Konkuk University Medical Center, Konkuk University, Seoul, Republic of Korea

⁸ Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Republic of Korea