Long-Term Effects of a Web-Based Low-FODMAP Diet Versus Probiotic Treatment for Irritable Bowel Syndrome, Including Shotgun Analyses of Microbiota: Randomized, Double-Crossover Clinical Trial

Dorit Vedel Ankersen   ¹ , BSc, MSc, PhD ;   Petra Weimers   ¹ , MD, PhD ;   Mette Bennedsen   ¹ , MD, PhD ;   Anne Birgitte Haaber   ² , MD ;   Eva Lund Fjordside   ¹ , MD ;   Moritz Emanuel Beber   ³ , PhD ;   Christian Lieven   ³ , PhD ;   Sanaz Saboori   ¹ , MD ;   Nicolai Vad   ¹ , MD ;   Terje Rannem   ¹ , MD ;   Dorte Marker   ¹ , RN ;   Kristine Paridaens   ⁴ , MD ;   Suzanne Frahm   ¹ , RD ;   Lisbeth Jensen   ⁵ , RD ;   Malte Rosager Hansen   ¹ , MD ;   Johan Burisch   ¹ , MD, PhD ;   Pia Munkholm   ¹ , MDSci

¹ Department of Gastroenterology, North Zealand University Hospital, Frederikssund, Denmark

² Private Gastro-clinic, Copenhagen, Denmark

³ Unseen Bio anpartsselskab, Copenhagen, Denmark

⁴ Ferring International Center Société Anonyme, Saint-Prex, Switzerland

⁵ Department of Dietetics, Herlev University Hospital, Herlev, Denmark