Dose-Response Effects of a Web-Based Physical Activity Program on Body Composition and Metabolic Health in Inactive Older Adults: Additional Analyses of a Randomized Controlled Trial

David P Vroege   ¹ , MD ;   Carolien A Wijsman   ¹ , MD, PhD ;   Karen Broekhuizen   ² , PhD ;   Anton JM de Craen   ¹ , PhD ;   Diana van Heemst   ¹ , PhD ;   Frans JG van der Ouderaa   ^{3, 4} , PhD ;   Willem van Mechelen   ⁵ , MD, PhD ;   P Eline Slagboom   ⁶ , PhD ;   Michael Catt   ⁷ , PhD ;   Rudi GJ Westendorp   ³ , MD, PhD ;   Evert ALM Verhagen   ⁵ , PhD ;   Simon P Mooijaart   ^{1, 2, 4} , MD, PhD

¹ Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands

² Institute for Evidence-Based Medicine in Old Age | IEMO, Leiden, Netherlands

³ Leyden Academy on Vitality and Ageing, Leiden, Netherlands

⁴ Netherlands Consortium for Healthy Aging, Leiden, Netherlands

⁵ Department of Public & Occupational Health and EMGO+ Institute, VU University Medical Center, Amsterdam, Netherlands

⁶ Department of Medical Statistics, section of Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands

⁷ Institute for Aging and Health, Newcastle University, Newcastle upon Tyne, United Kingdom