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Molecular Detection of SARS-CoV-2 From Throat Swabs Performed With or Without Specimen Collection From the Tonsils: Protocol for a Multicenter Randomized Controlled Trial

Molecular Detection of SARS-CoV-2 From Throat Swabs Performed With or Without Specimen Collection From the Tonsils: Protocol for a Multicenter Randomized Controlled Trial

A throat swab, alone or combined with a nasal swab, is a frequently used sample method in many countries [3-5]. However, there is considerable variability in the reported diagnostic accuracy of throat swabs, with a 95% CI from 52% to 100% reported in systematic reviews [6,7].

Benedikte Hartvigsen, Kathrine Kronberg Jakobsen, Thomas Benfield, Niels Tobias Gredal, Annette Kjær Ersbøll, Mathias Waldemar Grønlund, Henning Bundgaard, Mikkel Porsborg Andersen, Nina Steenhard, Christian von Buchwald, Tobias Todsen

JMIR Res Protoc 2024;13:e47446

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Internet Tool to Support Self-Assessment and Self-Swabbing of Sore Throat: Development and Feasibility Study

Internet Tool to Support Self-Assessment and Self-Swabbing of Sore Throat: Development and Feasibility Study

Another approach to improving the targeting of antibiotic use in patients with sore throat, which can be used alone or in combination with clinical scoring systems, is collecting throat swab samples for testing.

Mark Lown, Kirsten A Smith, Ingrid Muller, Catherine Woods, Emma Maund, Kirsty Rogers, Taeko Becque, Gail Hayward, Michael Moore, Paul Little, Margaret Glogowska, Alastair Hay, Beth Stuart, Efi Mantzourani, Christopher R Wilcox, Natalie Thompson, Nick A Francis

J Med Internet Res 2023;25:e39791

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An Agreement of Antigen Tests on Oral Pharyngeal Swabs or Less Invasive Testing With Reverse Transcription Polymerase Chain Reaction for Detecting SARS-CoV-2 in Adults: Protocol for a Prospective Nationwide Observational Study

An Agreement of Antigen Tests on Oral Pharyngeal Swabs or Less Invasive Testing With Reverse Transcription Polymerase Chain Reaction for Detecting SARS-CoV-2 in Adults: Protocol for a Prospective Nationwide Observational Study

Swabs for RATs will be tested immediately after sample collection, whereas sterile flocked nylon swabs for RT-PCR will be transferred to a NEST disposable sampler inactivation transport medium (NEST tube and Scientific Nasopharyngeal Specimen Collection Swab, Wuxi NEST Biotechnology Co., Ltd, Wuxi City, Jiangsu Province, China) and sent for RT-PCR. Samples for deep nasopharyngeal cavity testing will be collected only for RT-PCR to compare anatomical testing locations.

Uffe Vest Schneider, Jenny Dahl Knudsen, Anders Koch, Nikolai Søren Kirkby, Jan Gorm Lisby

JMIR Res Protoc 2022;11(5):e35706

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