Journal of Medical Internet Research

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#GenderAffirmingHormoneTherapy and Health Information on TikTok: Thematic Content Analysis

Julia Rose Beatini, Nora Yanyi Sun, Julianna K Coleman, Maetal E Haas-Kogan, Andrea Pelletier, Deborah Bartz, Alex Sogomon Keuroghlian

JMIR Infodemiology 2025;5:e66845

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Uncovering Social States in Healthy and Clinical Populations Using Digital Phenotyping and Hidden Markov Models: Observational Study

(E) The total dwell time was compared to clinical measures. (F) Lower socially active dwell time in AD versus HCs, and an interaction between socially active dwell time and AD when predicting social functioning, were observed. AD: Alzheimer disease; HC: healthy control; SCC: subjective cognitive complaints; SZ: schizophrenia; S1: state 1; S2: state 2; zt: hidden state at time point, t.

Imogen E Leaning, Andrea Costanzo, Raj Jagesar, Lianne M Reus, Pieter Jelle Visser, Martien J H Kas, Christian F Beckmann, Henricus G Ruhé, Andre F Marquand

J Med Internet Res 2025;27:e64007

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Are Treatment Services Ready for the Use of Big Data Analytics and AI in Managing Opioid Use Disorder?

Matthew Amer, Rosalind Gittins, Antonio Martinez Millana, Florian Scheibein, Marica Ferri, Babak Tofighi, Frank Sullivan, Margaret Handley, Monty Ghosh, Alexander Baldacchino, Joseph Tay Wee Teck

J Med Internet Res 2025;27:e58723

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Sex Differences in the Variability of Physical Activity Measurements Across Multiple Timescales Recorded by a Wearable Device: Observational Retrospective Cohort Study

The results from these tests and the distributions compared with these tests are shown in most of the figures and tables (Figures 1 C-E, 2 A-D, 3 D, and 4 A and 4 B; Figures S2-S5 in Multimedia Appendix 1). Population SDs of the subpopulations described were calculated for their relevance to power analysis (Tables S1 and S2 in Multimedia Appendix 1).

Kristin J Varner, Lauryn Keeler Bruce, Severine Soltani, Wendy Hartogensis, Stephan Dilchert, Frederick M Hecht, Anoushka Chowdhary, Leena Pandya, Subhasis Dasgupta, Ilkay Altintas, Amarnath Gupta, Ashley E Mason, Benjamin L Smarr

J Med Internet Res 2025;27:e66231

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Moderators’ Experiences of the Safety and Effectiveness of Patient Engagement in an Asthma Online Health Community: Exploratory Qualitative Interview Study

private message (ie, a message sent between users, not published on the OHC and only seen by moderators if reported by a user) was against the rules and when contacting users, the moderators mentioned that they often referred to a published set of community guidelines, which users agreed to abide by when they signed up to the OHC: If I get an inappropriate post, I review it to make sure what part of the terms and conditions it’s breaking, then I’ll delete the post and then I’ll send a warning to the member, via e-mail

Helen E Wood, Georgios Dimitrios Karampatakis, Neil S Coulson, Nishanth Sastry, Xiancheng Li, Stephanie J C Taylor, Chris J Griffiths, Anna De Simoni

J Med Internet Res 2025;27:e58167

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Family Caregiver Perspectives on Digital Methods to Measure Stress: Qualitative Descriptive Study

This included contacting previous study participants participating in a digital peer support program for caregivers of people with motor neurone disease [32], snowball sampling, social media (X, formerly known as Twitter), patient charities (ICUSteps and Motor Neurone Disease Association), the King’s College London weekly research volunteer e-circular, and through E-Carewell (research program of digital support tools for carers run by Ulster University).

Louise Rose, Sian Saha, Emily Flowers, Chee Siang Ang, Alexander J Casson, Joan Condell, Faith Matcham, Tony Robinson, John Rooksby