Characterizing Physical Activity Trajectories Preceding Incident Major Depressive Disorder Diagnosis With Consumer Wearable Devices in the All of Us Research Program: Retrospective Nested Case-Control Study

Yuezhou Zhang   ¹ , PhD ;   Amos A Folarin   ^{1, 2, 3, 4, 5} , PhD ;   Hugh Logan Ellis   ¹ , MBBCHIR, PhD ;   Rongrong Zhong   ^{1, 6} , MD ;   Callum Stewart   ¹ , PhD ;   Heet Sankesara   ¹ , BSc ;   Hyunju Kim   ¹ , PhD ;   Shaoxiong Sun   ^{1, 7} , PhD ;   Abhishek Pratap   ^{1, 8, 9} , PhD ;   Richard JB Dobson   ^{1, 2, 3, 4, 5} , PhD

¹ Department of Biostatistics & Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom

² Institute of Health Informatics, University College London, London, United Kingdom

³ NIHR Biomedical Research Centre at South London and Maudsley, NHS Foundation Trust, London, United Kingdom

⁴ NIHR Biomedical Research Centre at University College London Hospitals, NHS Foundation Trust, London, United Kingdom

⁵ Health Data Research UK, University College London, London, United Kingdom

⁶ Clinical Research Center & Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China

⁷ Department of Computer Science, University of Sheffield, Sheffield, United Kingdom

⁸ Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, United States

⁹ Department of Biomedical and Health Informatics, University of Washington, Seattle, WA, United States