Mediating Effects of Stigma and Depressive Symptoms in a Social Media–Based Intervention to Improve Long-term Quality of Life Among People Living With HIV: Secondary Analysis of a Randomized Controlled Trial

Yiran Li   ^{1 *} , MMSc ;   Yan Guo   ^{1, 2 *} , PhD ;   Y Alicia Hong   ³ , PhD ;   Chengbo Zeng   ^{4, 5} , PhD ;   Yu Zeng   ¹ , MMSc ;   Hanxi Zhang   ⁶ , PhD ;   Mengting Zhu   ⁷ , MS ;   Jiaying Qiao   ⁸ , MMSc ;   Weiping Cai   ⁹ , MD ;   Linghua Li   ⁹ , MD ;   Cong Liu   ⁹ , MSN

¹ Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China

² Sun Yat-sen Center for Global Health, Guangzhou, China

³ Department of Health Administration and Policy, College of Health and Human Services, George Mason University, Fairfax, VA, United States

⁴ South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States

⁵ Department of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, United States

⁶ National Center of AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

⁷ The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China

⁸ Department of Vital Statistics, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China

⁹ Department of Infectious diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China

*these authors contributed equally