Published on in Vol 23, No 10 (2021): October

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/31400, first published .
International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study

International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study

International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study

Authors of this article:

Griffin M Weber 1 Author Orcid Image ;   Harrison G Zhang 1 Author Orcid Image ;   Sehi L'Yi 1 Author Orcid Image ;   Clara-Lea Bonzel 1 Author Orcid Image ;   Chuan Hong 1 Author Orcid Image ;   Paul Avillach 1 Author Orcid Image ;   Alba Gutiérrez-Sacristán 1 Author Orcid Image ;   Nathan P Palmer 1 Author Orcid Image ;   Amelia Li Min Tan 1 Author Orcid Image ;   Xuan Wang 1 Author Orcid Image ;   William Yuan 1 Author Orcid Image ;   Nils Gehlenborg 1 Author Orcid Image ;   Anna Alloni 2 Author Orcid Image ;   Danilo F Amendola 3 Author Orcid Image ;   Antonio Bellasi 4 Author Orcid Image ;   Riccardo Bellazzi 5 Author Orcid Image ;   Michele Beraghi 6 Author Orcid Image ;   Mauro Bucalo 2 Author Orcid Image ;   Luca Chiovato 7 Author Orcid Image ;   Kelly Cho 8 Author Orcid Image ;   Arianna Dagliati 9 Author Orcid Image ;   Hossein Estiri 10 Author Orcid Image ;   Robert W Follett 11 Author Orcid Image ;   Noelia García Barrio 12 Author Orcid Image ;   David A Hanauer 13 Author Orcid Image ;   Darren W Henderson 14 Author Orcid Image ;   Yuk-Lam Ho 8 Author Orcid Image ;   John H Holmes 15, 16 Author Orcid Image ;   Meghan R Hutch 17 Author Orcid Image ;   Ramakanth Kavuluru 18 Author Orcid Image ;   Katie Kirchoff 19 Author Orcid Image ;   Jeffrey G Klann 10 Author Orcid Image ;   Ashok K Krishnamurthy 20 Author Orcid Image ;   Trang T Le 15 Author Orcid Image ;   Molei Liu 21 Author Orcid Image ;   Ne Hooi Will Loh 22 Author Orcid Image ;   Sara Lozano-Zahonero 23 Author Orcid Image ;   Yuan Luo 17 Author Orcid Image ;   Sarah Maidlow 24 Author Orcid Image ;   Adeline Makoudjou 23 Author Orcid Image ;   Alberto Malovini 25 Author Orcid Image ;   Marcelo Roberto Martins 26 Author Orcid Image ;   Bertrand Moal 27 Author Orcid Image ;   Michele Morris 28 Author Orcid Image ;   Danielle L Mowery 15 Author Orcid Image ;   Shawn N Murphy 29 Author Orcid Image ;   Antoine Neuraz 30 Author Orcid Image ;   Kee Yuan Ngiam 31 Author Orcid Image ;   Marina P Okoshi 32 Author Orcid Image ;   Gilbert S Omenn 33 Author Orcid Image ;   Lav P Patel 34 Author Orcid Image ;   Miguel Pedrera Jiménez 12 Author Orcid Image ;   Robson A Prudente 32 Author Orcid Image ;   Malarkodi Jebathilagam Samayamuthu 28 Author Orcid Image ;   Fernando J Sanz Vidorreta 11 Author Orcid Image ;   Emily R Schriver 35 Author Orcid Image ;   Petra Schubert 8 Author Orcid Image ;   Pablo Serrano Balazote 12 Author Orcid Image ;   Byorn WL Tan 36 Author Orcid Image ;   Suzana E Tanni 32 Author Orcid Image ;   Valentina Tibollo 25 Author Orcid Image ;   Shyam Visweswaran 28 Author Orcid Image ;   Kavishwar B Wagholikar 10 Author Orcid Image ;   Zongqi Xia 37 Author Orcid Image ;   Daniela Zöller 23 Author Orcid Image ;   The Consortium For Clinical Characterization Of COVID-19 By EHR (4CE) 1 ;   Isaac S Kohane 1 Author Orcid Image ;   Tianxi Cai 1 Author Orcid Image ;   Andrew M South 38 Author Orcid Image ;   Gabriel A Brat 1 Author Orcid Image
Griffin M Weber 1*, MD, PhD;  Harrison G Zhang 1*, HSDG;  Sehi L'Yi 1*, PhD;  Clara-Lea Bonzel 1, MSc;  Chuan Hong 1, PhD;  Paul Avillach 1, MD, PhD;  Alba Gutiérrez-Sacristán 1, PhD;  Nathan P Palmer 1, PhD;  Amelia Li Min Tan 1, BSc, PhD;  Xuan Wang 1, PhD;  William Yuan 1, PhD;  Nils Gehlenborg 1, PhD;  Anna Alloni 2, PhD;  Danilo F Amendola 3, MSc;  Antonio Bellasi 4, MD, PhD;  Riccardo Bellazzi 5, MS, PhD;  Michele Beraghi 6, MS;  Mauro Bucalo 2, MS;  Luca Chiovato 7, MD, PhD;  Kelly Cho 8, PhD;  Arianna Dagliati 9, MS, PhD;  Hossein Estiri 10, PhD;  Robert W Follett 11, BS;  Noelia García Barrio 12, MS;  David A Hanauer 13, MS, MD;  Darren W Henderson 14, BS;  Yuk-Lam Ho 8, MPH;  John H Holmes 15, 16, MS, PhD;  Meghan R Hutch 17, BS;  Ramakanth Kavuluru 18, PhD;  Katie Kirchoff 19, MSHI;  Jeffrey G Klann 10, MEng, PhD;  Ashok K Krishnamurthy 20, PhD;  Trang T Le 15, PhD;  Molei Liu 21, MSc;  Ne Hooi Will Loh 22, MBBS;  Sara Lozano-Zahonero 23, PhD;  Yuan Luo 17, PhD;  Sarah Maidlow 24, AA;  Adeline Makoudjou 23, MD;  Alberto Malovini 25, PhD;  Marcelo Roberto Martins 26, MSc;  Bertrand Moal 27, MD, PhD;  Michele Morris 28, BA;  Danielle L Mowery 15, PhD;  Shawn N Murphy 29, MD, PhD;  Antoine Neuraz 30, MD, PhD;  Kee Yuan Ngiam 31, MBBS, MRCS, MMed;  Marina P Okoshi 32, MD, PhD;  Gilbert S Omenn 33, MD, PhD;  Lav P Patel 34, MS;  Miguel Pedrera Jiménez 12, MS;  Robson A Prudente 32, PhD;  Malarkodi Jebathilagam Samayamuthu 28, MD;  Fernando J Sanz Vidorreta 11, BS;  Emily R Schriver 35, MS;  Petra Schubert 8, MPH;  Pablo Serrano Balazote 12, MS, MD;  Byorn WL Tan 36, MBBS;  Suzana E Tanni 32, MD, PhD;  Valentina Tibollo 25, MS;  Shyam Visweswaran 28, MD, PhD;  Kavishwar B Wagholikar 10, MBBS, PhD;  Zongqi Xia 37, MD, PhD;  Daniela Zöller 23, PhD;   The Consortium For Clinical Characterization Of COVID-19 By EHR (4CE) 1;  Isaac S Kohane 1, MD, PhD;  Tianxi Cai 1, ScD;  Andrew M South 38, MS, MD;  Gabriel A Brat 1, MPH, MD

1 Department of Biomedical Informatics, Harvard Medical School , Boston, MA, US

2 BIOMERIS (BIOMedical Research Informatics Solutions) , Pavia , IT

3 Clinical Research Unit, Botucatu Medical School, São Paulo State University, Botucatu , BR

4 Division of Nephrology, Department of Medicine, Ente Ospedaliero Cantonale, Lugano , CH

5 Department of Electrical, Computer and Biomedical Engineering, University of Pavia , Pavia , IT

6 Information Technology Department, Azienda Socio-Sanitaria Territoriale di Pavia , Pavia , IT

7 Unit of Internal Medicine and Endocrinology, Istituti Clinici Scientifici Maugeri SpA SB IRCCS , Pavia , IT

8 Massachusetts Veterans Epidemiology Research and Information Center, Veterans Affairs Boston Healthcare System , Boston, MA, US

9 Department of Electrical Computer and Biomedical Engineering, University of Pavia , Pavia , IT

10 Department of Medicine, Massachusetts General Hospital , Boston, MA, US

11 Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, US

12 Health Informatics, Hospital Universitario 12 de Octubre , Madrid , ES

13 Department of Learning Health Sciences, University of Michigan Medical School , Ann Arbor, MI, US

14 Department of Biomedical Informatics, University of Kentucky , Lexington, KY, US

15 Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA, US

16 Institute for Biomedical Informatics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA, US

17 Department of Preventive Medicine, Northwestern University , Chicago, IL, US

18 Institute for Biomedical Informatics, University of Kentucky , Lexington, KY, US

19 Medical University of South Carolina , Charleston, SC, US

20 Department of Computer Science, Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, US

21 Department of Biostatistics, Harvard T.H. Chan School of Public Health , Boston, MA, US

22 Department of Anaesthesia, National University Health System , Singapore , SG

23 Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg , DE

24 Michigan Institute for Clinical & Health Research Informatics, University of Michigan , Ann Arbor, MI, US

25 Laboratory of Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri SpA SB IRCCS , Pavia , IT

26 Clinical Hospital of Botucatu Medical School, São Paulo State University , Botucatu , BR

27 Informatique et archivistique médicales unit, Bordeaux University Hospital , Bordeaux , FR

28 Department of Biomedical Informatics, University of Pittsburgh , Pittsburgh, PA, US

29 Department of Neurology, Massachusetts General Hospital , Boston, MA, US

30 Department of Biomedical Informatics, Hôpital Necker-Enfants Malade, Assistance Publique Hôpitaux de Paris, University of Paris, Paris , FR

31 Department of Biomedical Informatics, Institute for Digital Medicine, National University Health System , Singapore , SG

32 Internal Medicine Department, Botucatu Medical School, São Paulo State University, Botucatu , BR

33 Department of Computational Medicine & Bioinformatics, Internal Medicine, Human Genetics, and Public Health, University of Michigan , Ann Arbor, MI, US

34 Division of Medical Informatics, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, US

35 Data Analytics Center, University of Pennsylvania Health System , Philadelphia, PA, US

36 Department of Medicine, National University Health System , Singapore , SG

37 Department of Neurology, University of Pittsburgh , Pittsburgh, PA, US

38 Section of Nephrology, Department of Pediatrics, Brenner Children's Hospital, Wake Forest School of Medicine, Winston Salem, NC, US

*these authors contributed equally

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