Management and Treatment of Patients With Obstructive Sleep Apnea Using an Intelligent Monitoring System Based on Machine Learning Aiming to Improve Continuous Positive Airway Pressure Treatment Compliance: Randomized Controlled Trial

Cecilia Turino   ^{1, 2 *} , MD ;   Ivan D Benítez   ^{1, 2 *} , BSc ;   Xavier Rafael-Palou   ^{3, 4} , PhD ;   Ana Mayoral   ⁵ , MD ;   Alejandro Lopera   ⁵ , MInf ;   Lydia Pascual   ^{1, 2} , BSc ;   Rafaela Vaca   ^{1, 2} , BSc ;   Anunciación Cortijo   ^{1, 2} , MD ;   Anna Moncusí-Moix   ^{1, 2} , MBioInf ;   Mireia Dalmases   ^{1, 2} , MD ;   Eloisa Vargiu   ³ , PhD ;   Jordi Blanco   ⁵ , MBus ;   Ferran Barbé   ^{1, 2} , MD ;   Jordi de Batlle   ^{1, 2} , PhD

¹ Group of Translational Research in Respiratory Medicine, Institut de Recerca Biomèdica de Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova and Santa Maria, Lleida, Spain

² Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain

³ eHealth Unit, Eurecat Centre Tecnòlogic de Catalunya, Barcelona, Spain

⁴ Barcelona Centre for New Medical Technologies (BCN Medtech), Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Spain

⁵ Oxigen salud, Barcelona, Spain

*these authors contributed equally