Published on in Vol 22, No 8 (2020): August

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/20193, first published .
Hazards of the Cytokine Storm and Cytokine-Targeted Therapy in Patients With COVID-19: Review

Hazards of the Cytokine Storm and Cytokine-Targeted Therapy in Patients With COVID-19: Review

Hazards of the Cytokine Storm and Cytokine-Targeted Therapy in Patients With COVID-19: Review

Authors of this article:

Miguel Quirch1 Author Orcid Image ;   Jeannie Lee1 Author Orcid Image ;   Shabnam Rehman1 Author Orcid Image

Journals

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  4. Luporini R, Rodolpho J, Kubota L, Martin A, Cominetti M, Anibal F, Pott-Junior H. IL-6 and IL-10 are associated with disease severity and higher comorbidity in adults with COVID-19. Cytokine 2021;143:155507 View
  5. Nyabi O, Bentahir M, Ambroise J, Bearzatto B, Chibani N, Smits B, Durant J, Vybornov A, Thellin O, El Moualij B, Gala J. Diagnostic Value of IgM and IgG Detection in COVID-19 Diagnosis by the Mobile Laboratory B-LiFE: A Massive Testing Strategy in the Piedmont Region. International Journal of Environmental Research and Public Health 2021;18(7):3372 View
  6. Trombetta A, Comar M, Tommasini A, Canton M, Campisciano G, Zanotta N, Cason C, Maso G, Risso F. SARS-CoV-2 Infection and Inflammatory Response in a Twin Pregnancy. International Journal of Environmental Research and Public Health 2021;18(6):3075 View
  7. Kozma G, Mészáros T, Bakos T, Hennies M, Bencze D, Uzonyi B, Győrffy B, Cedrone E, Dobrovolskaia M, Józsi M, Szebeni J. Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine Storm. Frontiers in Immunology 2021;12 View
  8. Maione F, Casillo G, Raucci F, Salvatore C, Ambrosini G, Costa L, Scarpa R, Caso F, Bucci M. Interleukin-17A (IL-17A): A silent amplifier of COVID-19. Biomedicine & Pharmacotherapy 2021;142:111980 View
  9. Fan Y, Wang Y, Yu S, Chang J, Yan Y, Wang Y, Bian Y. Natural products provide a new perspective for anti-complement treatment of severe COVID-19: a review. Chinese Medicine 2021;16(1) View
  10. Larionova R, Byvaltsev K, Kravtsova О, Takha E, Petrov S, Kazarian G, Valeeva A, Shuralev E, Mukminov M, Renaudineau Y, Arleevskaya M. SARS-Cov2 acute and post-active infection in the context of autoimmune and chronic inflammatory diseases. Journal of Translational Autoimmunity 2022;5:100154 View
  11. Binneboessel S, Bruno R, Wernly B, Masyuk M, Flaatten H, Fjølner J, Wolff G, Kelm M, Beil M, Sviri S, Szczeklik W, Leaver S, De Lange D, Guidet B, Jung C. Cytokine absorption in critically ill old COVID-19 patients with renal failure: A retrospective analysis of 503 intensive care unit patients. Clinical Hemorheology and Microcirculation 2023;85(2):105 View
  12. Yang X, You J, Wei Y, Li H, Gao L, Guo Q, Huang Y, Gong C, Yi C. Emerging nanomaterials applied for tackling the COVID-19 cytokine storm. Journal of Materials Chemistry B 2021;9(39):8185 View
  13. Korobova Z, Arsentieva N, Liubimova N, Dedkov V, Gladkikh A, Sharova A, Chernykh E, Kashchenko V, Ratnikov V, Gorelov V, Stanevich O, Kulikov A, Pevtsov D, Totolian A. A Comparative Study of the Plasma Chemokine Profile in COVID-19 Patients Infected with Different SARS-CoV-2 Variants. International Journal of Molecular Sciences 2022;23(16):9058 View
  14. Zhan W, Huang J, Zeng P, Tian W, Luo Z, Wu J. Emerging neurotropic features of SARS-CoV-2. Journal of Molecular Cell Biology 2021;13(10):705 View
  15. Salmerón-Godoy L, López-Alba A, Arranz-Canales E. Síndrome de activación macrofágica por COVID-19 en el adulto. Revista Española de Casos Clínicos en Medicina Interna 2021;6(1):3 View
  16. Kobak S. The Perfect Storm: A Rheumatologist's Point of View on COVID-19 Infection. Current Rheumatology Reviews 2021;17(2):141 View
  17. Chen Y, Wei J, Qin R, Hou J, Zang G, Zhang G, Chen T. Folic acid: a potential inhibitor against SARS-CoV-2 nucleocapsid protein. Pharmaceutical Biology 2022;60(1):862 View
  18. Rubio-Casillas A, Gupta R, Redwa E, Uversky V, Badierah R. Early taurine administration as a means for halting the cytokine storm progression in COVID-19 patients. Exploration of Medicine 2022:234 View
  19. Danilenko V, Devyatkin A, Marsova M, Shibilova M, Ilyasov R, Shmyrev V. Common Inflammatory Mechanisms in COVID-19 and Parkinson’s Diseases: The Role of Microbiome, Pharmabiotics and Postbiotics in Their Prevention. Journal of Inflammation Research 2021;Volume 14:6349 View
  20. Tolossa T, Merdassa Atomssa E, Fetensa G, Bayisa L, Ayala D, Turi E, Wakuma B, Mulisa D, Seyoum D, Getahun A, Shibiru T, Fekadu G, Desalegn M, Bikila H, Bongomin F. Acute respiratory distress syndrome among patients with severe COVID-19 admitted to treatment center of Wollega University Referral Hospital, Western Ethiopia. PLOS ONE 2022;17(6):e0267835 View
  21. Peng J, Li Q, Dong J, Yuan G, Wang D. Case Report: The Experience of Managing a Moderate ARDS Caused by SARS-CoV-2 Omicron BA.2 Variant in Chongqing, China: Can We Do Better?. Frontiers in Medicine 2022;9 View
  22. Tembhare P, Sriram H, Chatterjee G, Khanka T, Gokarn A, Mirgh S, Rajendra A, Chaturvedi A, Ghogale S, Deshpande N, Girase K, Dalvi K, Rajpal S, Patkar N, Trivedi B, Joshi A, Murthy V, Shetty N, Nair S, More A, Kamtalwar S, Chavan P, Bhat V, Bhat P, Subramanian P, Gupta S, Khattry N. Comprehensive immune cell profiling depicts an early immune response associated with severe coronavirus disease 2019 in cancer patients. Immunology & Cell Biology 2022;100(1):61 View
  23. Li J, Huang Z, Lu S, Luo H, Tan Y, Ye P, Liu X, Wu Z, Wu C, Stalin A, Wang H, Liu Y, Shen L, Fan X, Zhang B, Yi J, Yao L, Xu Y, Wu J, Duan X. Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking. Medicine 2021;100(51):e27112 View
  24. Fu B, Yin S, Lin X, Shi L, Wang Y, Zhang S, Zhao Q, Li Z, Yang Y, Wu H. PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure. Cell Death & Disease 2020;11(9) View
  25. Kabaeva E, Ershov A, Litvitskiy P, Rejepov D, Pozdnyakov A. Patterns and features of the course of the early and late stages recovery period after ischemic stroke associated with COVID-19. Meditsinskiy sovet = Medical Council 2023;(23):50 View
  26. Gabrielli M, Franza L, Esperide A, Gasparrini I, Gasbarrini A, Franceschi F. Liver Injury in Patients Hospitalized for COVID-19: Possible Role of Therapy. Vaccines 2022;10(2):192 View
  27. Lan Y, Wang H, Wu J, Meng X. Cytokine storm-calming property of the isoquinoline alkaloids in Coptis chinensis Franch. Frontiers in Pharmacology 2022;13 View
  28. Philips C, Rela M, Soin A, Gupta S, Surendran S, Augustine P. Critical Update on the Diagnosis and Management of COVID-19 in Advanced Cirrhosis and Liver Transplant Recipients. Journal of Clinical and Translational Hepatology 2021;000(000):000 View
  29. Kow C, Ramachandram D, Hasan S. The effect of higher-intensity dosing of anticoagulation on the clinical outcomes in hospitalized patients with COVID-19: A meta-analysis of randomized controlled trials. Journal of Infection and Chemotherapy 2022;28(2):257 View
  30. Julian D, Kazakoff M, Patel A, Jaynes J, Willis M, Yates C. Chemokine-Based Therapeutics for the Treatment of Inflammatory and Fibrotic Convergent Pathways in COVID-19. Current Pathobiology Reports 2021;9(4):93 View
  31. Murdaca G, Paladin F, Tonacci A, Isola S, Allegra A, Gangemi S. The Potential Role of Cytokine Storm Pathway in the Clinical Course of Viral Respiratory Pandemic. Biomedicines 2021;9(11):1688 View
  32. Coffin A, Dale E, Doppenberg E, Fearington F, Hayward T, Hill J, Molano O. Putative COVID-19 therapies imatinib, lopinavir, ritonavir, and ivermectin cause hair cell damage: A targeted screen in the zebrafish lateral line. Frontiers in Cellular Neuroscience 2022;16 View
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  34. Irún P, Gracia R, Piazuelo E, Pardo J, Morte E, Paño J, Boza J, Carrera-Lasfuentes P, Higuera G, Lanas A. Serum lipid mediator profiles in COVID-19 patients and lung disease severity: a pilot study. Scientific Reports 2023;13(1) View
  35. Stamatiou K, Magri V, Perletti G, Trinchieri A. SARS-CoV-2 and clinical urology: There is no dragon in this story. Hellenic Urology 2022;34(1):8 View
  36. Khafaei M, Asghari R, Zafari F, Sadeghi M. Impact of IL-6 rs1800795 and IL-17A rs2275913 gene polymorphisms on the COVID-19 prognosis and susceptibility in a sample of Iranian patients. Cytokine 2024;174:156445 View

Books/Policy Documents

  1. Adetunji C, Olaniyan O, Adeyomoye O, Dare A, Adeniyi M, Alex E, Rebezov M, Koriagina N, Shariati M. Assessing COVID-19 and Other Pandemics and Epidemics using Computational Modelling and Data Analysis. View
  2. Adetunji C, Olaniyan O, Adeyomoye O, Dare A, Adeniyi M, Alex E, Rebezov M, Petukhova E, Shariati M. Assessing COVID-19 and Other Pandemics and Epidemics using Computational Modelling and Data Analysis. View
  3. Trüeb R, Gavazzoni Dias M, Dutra Rezende H, de la Cruz Vargas Vilte R, Romiti R. Hair in Infectious Disease. View