This paper is in the following e-collection/theme issue:

Digital Health Reviews (1331) Web-based and Mobile Health Interventions (3358) Anxiety and Stress Disorders (1081) Behavior Change (723) Depression and Mood Disorders; Suicide Prevention (1393)

Published on in Vol 22, No 8 (2020): August

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/18100, first published .
Effects of Internet-Based Cognitive Behavioral Therapy in Routine Care for Adults in Treatment for Depression and Anxiety: Systematic Review and Meta-Analysis

Effects of Internet-Based Cognitive Behavioral Therapy in Routine Care for Adults in Treatment for Depression and Anxiety: Systematic Review and Meta-Analysis

Effects of Internet-Based Cognitive Behavioral Therapy in Routine Care for Adults in Treatment for Depression and Anxiety: Systematic Review and Meta-Analysis

Authors of this article:

Anne Etzelmueller1, 2, 3, 4 Author Orcid Image ;   Christiaan Vis3, 4 Author Orcid Image ;   Eirini Karyotaki3, 5 Author Orcid Image ;   Harald Baumeister6 Author Orcid Image ;   Nickolai Titov7 Author Orcid Image ;   Matthias Berking1 Author Orcid Image ;   Pim Cuijpers3, 4 Author Orcid Image ;   Heleen Riper3, 4, 8 Author Orcid Image ;   David Daniel Ebert1, 2, 3 Author Orcid Image
Article Authors Cited by (196) Tweetations (41) Metrics

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  94. Tarp K, Nielsen S, Holmberg T, Dalsgaard C, Borkner S, Skaarnes H, Jensen E, Piera-Jiménez J, Vis C, Mathiasen K. Therapist perceptions of the implementation of a new screening procedure using the ItFits-toolkit in an iCBT routine care clinic: A mixed-methods study using the consolidated framework for implementation research. Frontiers in Psychiatry 2023;14 View
  95. Stephenson C, Moghimi E, Gutierrez G, Jagayat J, Layzell G, Patel C, Omrani M, Alavi N. User experiences of an online therapist-guided psychotherapy platform, OPTT: A cross-sectional study. Internet Interventions 2023;32:100623 View
  96. Alavi N, Moghimi E, Stephenson C, Gutierrez G, Jagayat J, Kumar A, Shao Y, Miller S, Yee C, Stefatos A, Gholamzadehmir M, Abbaspour Z, Shirazi A, Gizzarelli T, Khan F, Patel C, Patel A, Yang M, Omrani M. Comparison of online and in-person cognitive behavioral therapy in individuals diagnosed with major depressive disorder: a non-randomized controlled trial. Frontiers in Psychiatry 2023;14 View
  97. Kheirkhah F, Faramarzi M, Shafierizi S, Chehrazi M, Basirat Z. Preliminary examination of acceptability, feasibility, and effectiveness of internet-based cognitive behavioral therapy for treatment of depression and anxiety in infertile women. Heliyon 2023;9(5):e15760 View
  98. Bischof G. Commentary on Hyland et al.: Digital treatment for alcohol use disorders ‐ challenges and opportunities. Addiction 2023;118(7):1244 View
  99. Held P, Wachen J. Concluding Comment: Posing Key Questions to Shape Future Research, Enhance Patient Outcomes, and Facilitate the Implementation of Intensive Treatments. Cognitive and Behavioral Practice 2023;30(3):417 View
  100. Achtyes E, Glenn T, Monteith S, Geddes J, Whybrow P, Martini J, Bauer M. Telepsychiatry in an Era of Digital Mental Health Startups. Current Psychiatry Reports 2023;25(6):263 View
  101. Zhang Q, Xu H, Wang Y, Jiang J, Xue Q, Qiu Z. Efficacy of cognitive behavioral therapy for reducing pain susceptibility and increasing social engagement in patients with chronic low back pain: A systematic review and meta-analysis. Medicine 2023;102(45):e35269 View
  102. Dowllah I, Melville C. Effectiveness of psychosocial interventions for post-traumatic stress disorder in refugees and asylum seekers resettled in low- and middle-income countries: A systematic review and meta-analysis. Journal of Health Psychology 2024;29(13):1463 View
  103. Wuthrich V, Dickson S, Pehlivan M, Chen J, Zagic D, Ghai I, Neelakandan A, Johnco C. Efficacy of low intensity interventions for geriatric depression and anxiety – A systematic review and meta-analysis. Journal of Affective Disorders 2024;344:592 View
  104. Guiney H, Mahoney A, Elders A, David C, Poulton R. Internet-based cognitive behavioural therapy in the real world: Naturalistic use and effectiveness of an evidence-based platform in New Zealand. Australian & New Zealand Journal of Psychiatry 2024;58(3):238 View
  105. Lisi D, Hawley L, McCabe R, Rowa K, Cameron D, Richter M, Rector N. Online versus in‐person delivery of cognitive behaviour therapy for obsessive compulsive disorder: An examination of effectiveness. Clinical Psychology & Psychotherapy 2024;31(1) View
  106. Haaf R, Machleid F, Köhler S. Überblick über Digitale Gesundheitsanwendungen mit Fokus Depression. Nervenheilkunde 2023;42(07/08):430 View
  107. Cross S, Staples L, Bisby M, Nielssen O, Fisher A, Titov N, Dear B. An open trial of the feasibility of brief internet-delivered acceptance and commitment therapy (iACT) for chronic anxiety and depression. Internet Interventions 2023;33:100655 View
  108. Maguire P, Bhullar N, Cosh S, Wootton B. Feasibility and acceptability of a remotely delivered transdiagnostic CBT treatment for postnatal anxiety and related disorders: A pilot case series. Women's Health 2023;19 View
  109. Andrews B, Klein B, Corboy D, McLaren S, Watson S. Therapist training in video chat technology for use in an adaptive digital mental health intervention: Challenges, facilitators and implications for training models. Counselling and Psychotherapy Research 2023;23(3):818 View
  110. Hurwitz C, Shiner C, Sharrock M, Millard M, Mahoney A. Mindfulness-enhanced internet-based cognitive behavioural therapy for anxiety and depression: Outcomes in routine care. Journal of Affective Disorders 2023;341:1 View
  111. Cross S, Nicholas J, Mangelsdorf S, Valentine L, Baker S, McGorry P, Gleeson J, Alvarez-Jimenez M. Developing a Theory of Change for a Digital Youth Mental Health Service (Moderated Online Social Therapy): Mixed Methods Knowledge Synthesis Study. JMIR Formative Research 2023;7:e49846 View
  112. Meyerhoff J, Beltzer M, Popowski S, Karr C, Nguyen T, Williams J, Krause C, Kumar H, Bhattacharjee A, Mohr D, Kornfield R. Small Steps over time: A longitudinal usability test of an automated interactive text messaging intervention to support self-management of depression and anxiety symptoms. Journal of Affective Disorders 2024;345:122 View
  113. Ryan A, Stearns-Yoder K, Brenner L. Real-World User Demographics of Three Web-Based Digital Mental Health Interventions Provided by the US Department of Veterans Affairs: Observational Study Using Web Analytics Data. JMIR Formative Research 2023;7:e48365 View
  114. Nielssen O, Staples L, Karin E, Ryan K, Kayrouz R, Dear B, Cross S, Titov N. Circumstances of suicide after registration with a national digital mental health service: an analysis of coroners’ reports. BJPsych Open 2023;9(3) View
  115. Haller K, Becker P, Niemeyer H, Boettcher J. Who benefits from guided internet-based interventions? A systematic review of predictors and moderators of treatment outcome. Internet Interventions 2023;33:100635 View
  116. Børtveit L, Nordgreen T, Nordahl-Hansen A. Therapists’ experiences with providing guided internet-delivered cognitive behavioral therapy for patients with mild and moderate depression: a thematic analysis. Frontiers in Psychology 2023;14 View
  117. Cohen Rodrigues T, Breeman L, Kinik A, Reijnders T, Dusseldorp E, Janssen V, Kraaijenhagen R, Atsma D, Evers A. Effectiveness of Human-Supported and Self-Help eHealth Lifestyle Interventions for Patients With Cardiometabolic Risk Factors: A Meta-Analysis. Psychosomatic Medicine 2023;85(9):795 View
  118. Bielinski L, Wälchli G, Nissen C, Berger T, Moggi F. Does an Internet-Based Emotion Regulation Intervention Provide Added Value for Acute Psychiatric Inpatient Care? Protocol for a Randomized Controlled Pilot Trial. JMIR Research Protocols 2023;12:e47656 View
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  121. Higson L, O'Brien T, Rayner G, Alpitsis R, Winton-Brown T. Content or context? A study protocol for a three-arm parallel randomised controlled trial of Re-PROGRAM, a brief internet-based intervention for patients with functional seizures. BMJ Open 2023;13(10):e072835 View
  122. Boberg J, Kaldo V, Mataix-Cols D, Crowley J, Roelstraete B, Halvorsen M, Forsell E, Isacsson N, Sullivan P, Svanborg C, Andersson E, Lindefors N, Kravchenko O, Mattheisen M, Danielsdottir H, Ivanova E, Boman M, Fernández de la Cruz L, Wallert J, Rück C. Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH). BMJ Open 2023;13(10):e069427 View
  123. Usluoglu F, Balık E. Child therapists’ views and experiences of video conference psychotherapy with children. Current Psychology 2024;43(7):6309 View
  124. Li B, Wang J. Research status of internet-delivered cognitive behavioral therapy in cancer patients. World Journal of Psychiatry 2023;13(11):831 View
  125. Hadjistavropoulos H, Hill T, Philipp-Muller A, Dear B, Titov N. Perceptions of client stories in internet-delivered cognitive behaviour therapy: A mixed-methods evaluation. Internet Interventions 2023;34:100692 View
  126. Cohen Rodrigues T, Reijnders T, Breeman L, Janssen V, Kraaijenhagen R, Atsma D, Evers A. Use Intention and User Expectations of Human-Supported and Self-Help eHealth Interventions: Internet-Based Randomized Controlled Trial. JMIR Formative Research 2024;8:e38803 View
  127. Stephenson C, Moghimi E, Shao Y, Kumar A, Yee C, Miller S, Stefatos A, Gholamzadehmir M, Abbaspour Z, Jagayat J, Shirazi A, Gizzarelli T, Gutierrez G, Khan F, Patel C, Patel A, Yang M, Omrani M, Alavi N. Comparing the efficacy of electronic cognitive behavioral therapy to medication and combination therapy for generalized anxiety disorder: a quasi-experimental clinical trial. Frontiers in Psychiatry 2023;14 View
  128. Børtveit L, Nordgreen T, Nordahl-Hansen A. Corrigendum: Therapists' experiences with providing guided internet-delivered cognitive behavioral therapy for patients with mild and moderate depression: a thematic analysis. Frontiers in Psychology 2023;14 View
  129. Andersson G. Innovating CBT and Answering New Questions: the Role of Internet-Delivered CBT. International Journal of Cognitive Therapy 2023;17(2):179 View
  130. Van Daele T, Vis C, Van Assche E, Riper H. Editorial: Dissemination, implementation and uptake of digital and technological interventions in practice. Frontiers in Digital Health 2024;5 View
  131. Zhu B, Hou Y, Yu X, Jiang M, Lu M, Shang M, Zhen H, Gu Y, Li H, Tao F. A hybrid effectiveness-implementation trial of application-based tiered care (Mom’s Good Mood) in treating perinatal anxiety within a primary health care system in China. BMJ Global Health 2024;9(1):e013604 View
  132. Beck C, Peynenburg V, Patterson T, Titov N, Dear B, Hadjistavropoulos H. Acceptability and effectiveness study of therapist-assisted internet-delivered cognitive behaviour therapy for agriculture producers. Internet Interventions 2024;35:100709 View
  133. Zhu M, Lai M, Chen R, Zhang Q. Web-Based Compassion Interventions for Family Caregivers' Mental Well-Being: A Systematic Review and Meta-Analysis. Journal of the American Medical Directors Association 2024;25(5):802 View
  134. Anastasiadou D, Herrero P, Garcia-Royo P, Vázquez-De Sebastián J, Slater M, Spanlang B, Álvarez de la Campa E, Ciudin A, Comas M, Ramos-Quiroga J, Lusilla-Palacios P. Clinical Efficacy of a Virtual Reality Tool for the Treatment of Obesity: Randomized Controlled Trial (Preprint). Journal of Medical Internet Research 2023 View
  135. Tutus D, Niemitz M, Plener P, Fegert J, Lehmann C, Weiss C, Knaevelsrud C, Biehl L, Rassenhofer M. A web-based psychological support program for caregivers of children with rare chronic diseases: a randomized controlled trial. Orphanet Journal of Rare Diseases 2024;19(1) View
  136. Andersson G. The latest developments with internet-based psychological treatments for depression. Expert Review of Neurotherapeutics 2024;24(2):171 View
  137. Etzelmueller A, Heber E, Horvath H, Radkovsky A, Lehr D, Ebert D. The Evaluation of the GET.ON Nationwide Web-Only Treatment Service for Depression- and Stress-Related Symptoms: Naturalistic Trial. Journal of Medical Internet Research 2024;26:e42976 View
  138. Posselt J, Baumann E, Dierks M. A qualitative interview study of patients' attitudes towards and intention to use digital interventions for depressive disorders on prescription. Frontiers in Digital Health 2024;6 View
  139. Sin J. An AI chatbot for talking therapy referrals. Nature Medicine 2024;30(2):350 View
  140. Josifovski N, Torok M, Batterham P, Wong Q, Beames J, Theobald A, Holland S, Huckvale K, Riley J, Cockayne N, Christensen H, Larsen M. Efficacy of BrighterSide, a Self-Guided App for Suicidal Ideation: Randomized Controlled Trial. JMIR Mental Health 2024;11:e55528 View
  141. Cohen Rodrigues T, de Buisonjé D, Reijnders T, Santhanam P, Kowatsch T, Breeman L, Janssen V, Kraaijenhagen R, Atsma D, Evers A. Human cues in eHealth to promote lifestyle change: An experimental field study to examine adherence to self-help interventions. Internet Interventions 2024;35:100726 View
  142. Kählke F, Hasking P, Küchler A, Baumeister H. Mental health services for German university students: acceptance of intervention targets and preference for delivery modes. Frontiers in Digital Health 2024;6 View
  143. Mayer G, Lemmer D, Michelsen I, Schrader P, Friederich H, Bauer S. Views of German mental health professionals on the use of digital mental health interventions for eating disorders: a qualitative interview study. Journal of Eating Disorders 2024;12(1) View
  144. Edmonds M, Peynenburg V, Kaldo V, Jernelöv S, Titov N, Dear B, Hadjistavropoulos H. Treating comorbid insomnia in patients enrolled in therapist-assisted transdiagnostic internet-delivered cognitive behaviour therapy for anxiety and depression: A randomized controlled trial. Internet Interventions 2024;35:100729 View
  145. Newby J, Upton E, Mason E, Black M. Technology-based Cognitive Behavioral Therapy Interventions. Psychiatric Clinics of North America 2024;47(2):399 View
  146. Kolaas K, Berman A, Hedman-Lagerlöf E, Lindsäter E, Hybelius J, Axelsson E. Internet-delivered transdiagnostic psychological treatments for individuals with depression, anxiety or both: a systematic review with meta-analysis of randomised controlled trials. BMJ Open 2024;14(4):e075796 View
  147. Ocisková M, Praško J, Holomany J. Online interventions for individuals with symptoms of depression. Psychiatrie pro praxi 2024;25(1):22 View
  148. Lorente-Català R, Font-Furnieles P, Escriva-Sanchis R, Bertó-García C, Vera-Albero P, García-Palacios A. Telephone support vs. self-guidance in an Internet-based self-administered psychological program for the treatment of depression: Protocol for a hybrid type 1 effectiveness-implementation randomized controlled trial. Internet Interventions 2024;36:100742 View
  149. Fang L, Lung Y, Hui G, Pang N, Smith M, Azizi T. Service Utilisation of an Innovative Mental Health Counselling Clinic. The British Journal of Social Work 2024;54(6):2603 View
  150. Murphy L, Saab M, Cornally N, McHugh S, Cotter P. Cardiovascular disease risk assessment in patients with rheumatoid arthritis: A scoping review. Clinical Rheumatology 2024;43(7):2187 View
  151. Gunawardena T, Bartholmae M, Karpov M, Dod R, Ahuja K, Rajendran A, Kathrotia M, Dodani S. Predictors for interest to participate in digital mental health therapy: a cross-sectional survey of individuals with anxiety and depression. BMC Digital Health 2024;2(1) View
  152. Goetter E, Yuen E. Technological Advances in Treating Anxiety Disorders. Psychiatric Clinics of North America 2024;47(4):813 View
  153. Kählke F, Pyttlik A, Küchler A, Baumeister H. Die psychische Gesundheit Studierender mit digitalen Angeboten fördern. Public Health Forum 2024;32(2):88 View
  154. Wei F, He R, Yang X, Hu Z, Wang Y. Cognitive–behavioural therapy effectiveness for fear of cancer recurrence: systematic review and meta-analysis. BMJ Supportive & Palliative Care 2024:spcare-2023-004639 View
  155. El‐Haj‐Mohamad R, Böttche M, Vöhringer M, Specht F, Stammel N, Nesterko Y, Knaevelsrud C, Wagner B. An internet‐based cognitive behavioural intervention for adults with depression in Arabic‐speaking countries: A randomized controlled trial. Stress and Health 2024;40(5) View
  156. Chen J, Li C, An K, Dong X, Liu J, Wu H. Effectiveness of telemedicine on common mental disorders: An umbrella review and meta-meta-analysis. Computers in Human Behavior 2024;159:108325 View
  157. Kohlmann S, Sikorski F, König H, Schütt M, Zapf A, Löwe B. The efficacy of automated feedback after internet-based depression screening (DISCOVER): an observer-masked, three-armed, randomised controlled trial in Germany. The Lancet Digital Health 2024;6(7):e446 View
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  174. Debrot A, Efinger L, Kheyar M, Pomini V, Berthoud L. A French-Language Web-Based Intervention Targeting Prolonged Grief Symptoms in People Who Are Bereaved and Separated: Randomized Controlled Trial. JMIR Formative Research 2024;8:e57294 View
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Books/Policy Documents

  1. Cuijpers P, Karyotaki E, Riper H. Comprehensive Clinical Psychology. View
  2. Jiménez-Molina Á, Franco P, Mac-Ginty S, Martínez V. Prevention and Early Treatment of Depression Through the Life Course. View
  3. Andersson G, Carlbring P. Comprehensive Clinical Psychology. View
  4. Andersson G. Mental Health in a Digital World. View
  5. Sextl-Plötz T, Franke M, Baumeister H, Ebert D. Digitale Gesundheitsinterventionen. View
  6. Sooradas S, Vatsa A, Negi A, Singh H, Mantri A, Khedkar S, Varshney R. Community Mental Health and Well-Being in the New Normal. View
  7. Drüge M, Guthardt L, Haller E, Michalak J, Apolinário-Hagen J. Recent Advances and Challenges in the Treatment of Major Depressive Disorder. View
  8. Efinger L, Kheyar M, Pomini V, Berthoud L, Wicki R, Debrot A. A Comprehensive Overview of Telemedicine. View