This paper is in the following e-collection/theme issue:

Web-based and Mobile Health Interventions (3114) mHealth for Wellness, Behavior Change and Prevention (2743) mHealth for Treatment Adherence (384) Fitness Trackers and Smart Pedometers/Accelerometers (541) Implantable Drug Delivery Systems, Ingestible Sensors and Digital Pills (14)

Published on in Vol 19, No 7 (2017): July

Effectiveness of Digital Medicines to Improve Clinical Outcomes in Patients with Uncontrolled Hypertension and Type 2 Diabetes: Prospective, Open-Label, Cluster-Randomized Pilot Clinical Trial

Effectiveness of Digital Medicines to Improve Clinical Outcomes in Patients with Uncontrolled Hypertension and Type 2 Diabetes: Prospective, Open-Label, Cluster-Randomized Pilot Clinical Trial

Effectiveness of Digital Medicines to Improve Clinical Outcomes in Patients with Uncontrolled Hypertension and Type 2 Diabetes: Prospective, Open-Label, Cluster-Randomized Pilot Clinical Trial

Authors of this article:

Juan Frias1 Author Orcid Image ;   Naunihal Virdi2 Author Orcid Image ;   Praveen Raja2 Author Orcid Image ;   Yoona Kim2 Author Orcid Image ;   George Savage2 Author Orcid Image ;   Lars Osterberg3 Author Orcid Image
Article Authors Cited by (149) Tweetations (51) Metrics

Journals

  1. Golledge J, Fernando M, Lazzarini P, Najafi B, G. Armstrong D. The Potential Role of Sensors, Wearables and Telehealth in the Remote Management of Diabetes-Related Foot Disease. Sensors 2020;20(16):4527 View
  2. Sá J, Garcia L, Bernuci M, Yamaguchi M. Scientometrics on interventions used for adherence of hypertension and diabetes therapies. Einstein (São Paulo) 2019;18 View
  3. Virdi N. Use of a Digital Medicine Offering in Hypertension Management: A Case Series. Pharmacy & Pharmacology International Journal 2017;5(5) View
  4. Martani A, Geneviève L, Poppe C, Casonato C, Wangmo T. Digital pills: a scoping review of the empirical literature and analysis of the ethical aspects. BMC Medical Ethics 2020;21(1) View
  5. Bartlett Ellis R, Hill J, Kerley K, Sinha A, Ganci A, Russell C. The Feasibility of a Using a Smart Button Mobile Health System to Self-Track Medication Adherence and Deliver Tailored Short Message Service Text Message Feedback. JMIR Formative Research 2019;3(2):e13558 View
  6. Chai P, Carreiro S, Innes B, Chapman B, Schreiber K, Edwards R, Carrico A, Boyer E. Oxycodone Ingestion Patterns in Acute Fracture Pain With Digital Pills. Anesthesia & Analgesia 2017;125(6):2105 View
  7. Shcherbakova N, Desselle S. Looking Back at US Pharmacy’s Past to Help Discern Its Future. Annals of Pharmacotherapy 2020;54(9):907 View
  8. Bharti S, Bharti B. Adherence to Antihypertensive Therapy: A Missing Link Between Treatment and Outcomes. American Journal of Hypertension 2018;31(3):290 View
  9. Emani S. Editorial commentary: Technology to treat heart failure: Friend or foe?. Trends in Cardiovascular Medicine 2018;28(7):489 View
  10. Hansen A, Herrmann M, Ehlers J, Mondritzki T, Hensel K, Truebel H, Boehme P. Perception of the Progressing Digitization and Transformation of the German Health Care System Among Experts and the Public: Mixed Methods Study. JMIR Public Health and Surveillance 2019;5(4):e14689 View
  11. Snyder C, Dorsey E, Atreja A. The Best Digital Biomarkers Papers of 2017. Digital Biomarkers 2018;2(2):64 View
  12. Chandler J, Sox L, Kellam K, Feder L, Nemeth L, Treiber F. Impact of a Culturally Tailored mHealth Medication Regimen Self-Management Program upon Blood Pressure among Hypertensive Hispanic Adults. International Journal of Environmental Research and Public Health 2019;16(7):1226 View
  13. Bonacini M, Kim Y, Pitney C, McKoin L, Tran M, Landis C. Wirelessly Observed Therapy to Optimize Adherence and Target Interventions for Oral Hepatitis C Treatment: Observational Pilot Study. Journal of Medical Internet Research 2020;22(2):e15532 View
  14. Plowman R, Peters S, Brady B, Osterberg L. Revealing Novel IDEAS: A Fiduciary Framework for Team-Based Prescribing. Academic Medicine 2020;95(8):1186 View
  15. Treskes R, van Winden L, van Keulen N, Atsma D, van der Velde E, van den Akker-van Marle E, Mertens B, Schalij M. Using Smart Technology to Improve Outcomes in Myocardial Infarction Patients: Rationale and Design of a Protocol for a Randomized Controlled Trial, The Box. JMIR Research Protocols 2017;6(9):e186 View
  16. Palacholla R, Fischer N, Coleman A, Agboola S, Kirley K, Felsted J, Katz C, Lloyd S, Jethwani K. Provider- and Patient-Related Barriers to and Facilitators of Digital Health Technology Adoption for Hypertension Management: Scoping Review. JMIR Cardio 2019;3(1):e11951 View
  17. Burnier M, Egan B. Adherence in Hypertension. Circulation Research 2019;124(7):1124 View
  18. Triplett K, El‐Behadli A, Masood S, Sullivan S, Desai D. Digital medicine program with pediatric solid organ transplant patients: Perceived benefits and challenges. Pediatric Transplantation 2019;23(7) View
  19. Levy A, Huang C, Huang A, Michael Ho P. Recent Approaches to Improve Medication Adherence in Patients with Coronary Heart Disease: Progress Towards a Learning Healthcare System. Current Atherosclerosis Reports 2018;20(1) View
  20. Jacobsen M, Dembek T, Kobbe G, Gaidzik P, Heinemann L. Noninvasive Continuous Monitoring of Vital Signs With Wearables: Fit for Medical Use?. Journal of Diabetes Science and Technology 2021;15(1):34 View
  21. Wechkunanukul K, Parajuli D, Hamiduzzaman M. Utilising digital health to improve medication-related quality of care for hypertensive patients: An integrative literature review. World Journal of Clinical Cases 2020;8(11):2266 View
  22. Rosenbaum L. Swallowing a Spy — The Potential Uses of Digital Adherence Monitoring. New England Journal of Medicine 2018;378(2):101 View
  23. Etminani K, Tao Engström A, Göransson C, Sant’Anna A, Nowaczyk S. How Behavior Change Strategies are Used to Design Digital Interventions to Improve Medication Adherence and Blood Pressure Among Patients With Hypertension: Systematic Review. Journal of Medical Internet Research 2020;22(4):e17201 View
  24. Spinelli M, Haberer J, Chai P, Castillo-Mancilla J, Anderson P, Gandhi M. Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions. Current HIV/AIDS Reports 2020;17(4):301 View
  25. Park S, Zhang Y, Rogers J, Gallon L. Recent advances of biosensors for hypertension and nephrology. Current Opinion in Nephrology and Hypertension 2019;28(4):390 View
  26. Xiong S, Berkhouse H, Schooler M, Pu W, Sun A, Gong E, Yan L. Effectiveness of mHealth Interventions in Improving Medication Adherence Among People with Hypertension: a Systematic Review. Current Hypertension Reports 2018;20(10) View
  27. Hajat C, Stein E. The global burden of multiple chronic conditions: A narrative review. Preventive Medicine Reports 2018;12:284 View
  28. Roseleur J, Harvey G, Stocks N, Karnon J. Behavioral Economic Insights to Improve Medication Adherence in Adults with Chronic Conditions: A Scoping Review. The Patient - Patient-Centered Outcomes Research 2019;12(6):571 View
  29. Steiger C, Abramson A, Nadeau P, Chandrakasan A, Langer R, Traverso G. Ingestible electronics for diagnostics and therapy. Nature Reviews Materials 2018;4(2):83 View
  30. Gandhi M, Bacchetti P, Spinelli M, Okochi H, Baeten J, Siriprakaisil O, Klinbuayaem V, Rodrigues W, Wang G, Vincent M, Cressey T, Drain P. Brief Report: Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cutoff for a Point-of-Care Test. JAIDS Journal of Acquired Immune Deficiency Syndromes 2019;81(1):72 View
  31. El Hadidi S, Rosano G. Evidence beyond the digital medication pill. European Heart Journal - Cardiovascular Pharmacotherapy 2020;6(2):72 View
  32. Su M, Haldane V, Upshur R, Sullivan F, Légaré F, Greiver M, Wei X. The Impact of Treatment Adherence for Patients With Diabetes and Hypertension on Cardiovascular Disease Risk: Protocol for a Retrospective Cohort Study, 2008-2018. JMIR Research Protocols 2019;8(5):e13571 View
  33. Beardslee L, Banis G, Chu S, Liu S, Chapin A, Stine J, Pasricha P, Ghodssi R. Ingestible Sensors and Sensing Systems for Minimally Invasive Diagnosis and Monitoring: The Next Frontier in Minimally Invasive Screening. ACS Sensors 2020;5(4):891 View
  34. Milman T, Joundi R, Alotaibi N, Saposnik G. Clinical inertia in the pharmacological management of hypertension. Medicine 2018;97(25):e11121 View
  35. Watson H, Tribe R, Shennan A. The role of medical smartphone apps in clinical decision-support: A literature review. Artificial Intelligence in Medicine 2019;100:101707 View
  36. Sulkowski M, Luetkemeyer A, Wyles D, Martorell C, Muir A, Weisberg I, Gordon S, McLain R, Huhn G. Impact of a digital medicine programme on hepatitis C treatment adherence and efficacy in adults at high risk for non‐adherence. Alimentary Pharmacology & Therapeutics 2020;51(12):1384 View
  37. Gatwood J, Hohmeier K, Brooks I. Beyond the reminder: The next steps in pharmacist-driven, mHealth patient engagement. Journal of the American Pharmacists Association 2019;59(2):S21 View
  38. Lu X, Yang H, Xia X, Lu X, Lin J, Liu F, Gu D. Interactive Mobile Health Intervention and Blood Pressure Management in Adults. Hypertension 2019;74(3):697 View
  39. Omboni S, McManus R, Bosworth H, Chappell L, Green B, Kario K, Logan A, Magid D, Mckinstry B, Margolis K, Parati G, Wakefield B. Evidence and Recommendations on the Use of Telemedicine for the Management of Arterial Hypertension. Hypertension 2020;76(5):1368 View
  40. Hamrahian S. Medication Non-adherence: a Major Cause of Resistant Hypertension. Current Cardiology Reports 2020;22(11) View
  41. Andrade A, Roughead E. Consumer‐directed technologies to improve medication management and safety. Medical Journal of Australia 2019;210(S6) View
  42. Lin C, Khan H, Chang R, Liao W, Chen Y, Siao S, Hsieh T. A study on the impact of poor medication adherence on health status and medical expense for diabetes mellitus patients in Taiwan. Medicine 2020;99(26):e20800 View
  43. Knights J, Heidary Z, Peters-Strickland T, Ramanathan M. Evaluating digital medicine ingestion data from seriously mentally ill patients with a Bayesian Hybrid Model. npj Digital Medicine 2019;2(1) View
  44. Van Biesen W, Decruyenaere J, Sideri K, Cockbain J, Sterckx S. Remote digital monitoring of medication intake: methodological, medical, ethical and legal reflections. Acta Clinica Belgica 2021;76(3):209 View
  45. Plowman R, Peters-Strickland T, Savage G. Digital medicines: clinical review on the safety of tablets with sensors. Expert Opinion on Drug Safety 2018;17(9):849 View
  46. Alipour A, Gabrielson S, Patel P. Ingestible Sensors and Medication Adherence: Focus on Use in Serious Mental Illness. Pharmacy 2020;8(2):103 View
  47. Chan C, Sounderajah V, Acharya A, Normahani P, Bicknell C, Riga C. The Role of Wearable Technologies and Telemonitoring in Managing Vascular Disease. Vascular and Endovascular Review 2020;3 View
  48. Papola D, Gastaldon C, Ostuzzi G. Can a digital medicine system improve adherence to antipsychotic treatment?. Epidemiology and Psychiatric Sciences 2018;27(3):227 View
  49. Biersteker T, Boogers M, de Lind van Wijngaarden R, Groenwold R, Trines S, van Alem A, Kirchhof C, van Hof N, Klautz R, Schalij M, Treskes R. Use of Smart Technology for the Early Diagnosis of Complications After Cardiac Surgery: The Box 2.0 Study Protocol. JMIR Research Protocols 2020;9(4):e16326 View
  50. Postel-Vinay N, Reach G, Eveillard P. Observance et nouvelles technologies : nouveau regard sur une problématique ancienne. médecine/sciences 2018;34(8-9):723 View
  51. Shader R. Adherence Measurements in Clinical Trials and Care. Clinical Therapeutics 2018;40(1):1 View
  52. Haga S. Toward digital-based interventions for medication adherence and safety. Expert Opinion on Drug Safety 2020;19(6):735 View
  53. Purswani J, Dicker A, Champ C, Cantor M, Ohri N. Big Data From Small Devices: The Future of Smartphones in Oncology. Seminars in Radiation Oncology 2019;29(4):338 View
  54. Steinmetz M, Rammos C, Rassaf T, Lortz J. Digital interventions in the treatment of cardiovascular risk factors and atherosclerotic vascular disease. IJC Heart & Vasculature 2020;26:100470 View
  55. Moutel G, Grandazzi G, Duchange N, Darquy S. Le médicament connecté, entre bienveillance et surveillance. médecine/sciences 2018;34(8-9):717 View
  56. Zhang W, Cheng B, Zhu W, Huang X, Shen C. Effect of Telemedicine on Quality of Care in Patients with Coexisting Hypertension and Diabetes: A Systematic Review and Meta-Analysis. Telemedicine and e-Health 2021;27(6):603 View
  57. Gershkowitz B, Hillert C, Crotty B. Digital Coaching Strategies to Facilitate Behavioral Change in Type 2 Diabetes: A Systematic Review. The Journal of Clinical Endocrinology & Metabolism 2021;106(4):e1513 View
  58. Wrzal P, Bunko A, Myageri V, Kukaswadia A, Neish C, Ivers N. Strategies to Overcome Therapeutic Inertia in Type 2 Diabetes Mellitus: A Scoping Review. Canadian Journal of Diabetes 2021;45(3):273 View
  59. Liu A, Laborde N, Coleman K, Vittinghoff E, Gonzalez R, Wilde G, Thorne A, Ikeguchi E, Shafner L, Sunshine L, van der Straten A, Siegler A, Buchbinder S. DOT Diary: Developing a Novel Mobile App Using Artificial Intelligence and an Electronic Sexual Diary to Measure and Support PrEP Adherence Among Young Men Who Have Sex with Men. AIDS and Behavior 2021;25(4):1001 View
  60. Shah N, Adusumalli S. Nudges and The Meaningful Adoption of Digital Health. Personalized Medicine 2020;17(6):429 View
  61. Klonoff D, Zhang J, Shang T, Mehta C, Kerr D. Pharmacoadherence: An Opportunity for Digital Health to Inform the Third Dimension of Pharmacotherapy for Diabetes. Journal of Diabetes Science and Technology 2021;15(1):177 View
  62. Rivas Yepes L, Demir E, Lee J, Sun R, Smuck M, Araci I. Skin Mountable Capillaric Strain Sensor with Ultrahigh Sensitivity and Direction Specificity. Advanced Materials Technologies 2020;5(12) View
  63. Nan J, Jia R, Meng S, Jin Y, Chen W, Hu H. The Impact of the COVID-19 Pandemic and the Importance of Telemedicine in Managing Acute ST Segment Elevation Myocardial Infarction Patients: Preliminary Experience and Literature Review. Journal of Medical Systems 2021;45(1) View
  64. Mao Y, Lin W, Wen J, Chen G. Impact and efficacy of mobile health intervention in the management of diabetes and hypertension: a systematic review and meta-analysis. BMJ Open Diabetes Research & Care 2020;8(1):e001225 View
  65. Yatabe J, Yatabe M, Ichihara A. The current state and future of internet technology-based hypertension management in Japan. Hypertension Research 2021;44(3):276 View
  66. Delva S, Waligora Mendez K, Cajita M, Koirala B, Shan R, Wongvibulsin S, Vilarino V, Gilmore D, Han H. Efficacy of Mobile Health for Self-management of Cardiometabolic Risk Factors. Journal of Cardiovascular Nursing 2021;36(1):34 View
  67. Poulter N, Borghi C, Parati G, Pathak A, Toli D, Williams B, Schmieder R. Medication adherence in hypertension. Journal of Hypertension 2020;38(4):579 View
  68. Denicolò S, Perco P, Thöni S, Mayer G. Non-adherence to antidiabetic and cardiovascular drugs in type 2 diabetes mellitus and its association with renal and cardiovascular outcomes: A narrative review. Journal of Diabetes and its Complications 2021;35(7):107931 View
  69. Erras A, Shahrvini B, Weinreb R, Baxter S. Review of glaucoma medication adherence monitoring in the digital health era. British Journal of Ophthalmology 2023;107(2):153 View
  70. Mansel C, Sarnataro R, Liu P. A critical evaluation of the National Innovation Accelerator programme: comparing eHealth and medical device-based innovations. British Journal of Healthcare Management 2021;27(4):1 View
  71. Daly A, Hovorka R. Technology in the management of type 2 diabetes: Present status and future prospects. Diabetes, Obesity and Metabolism 2021;23(8):1722 View
  72. Al-Arkee S, Mason J, Lane D, Fabritz L, Chua W, Haque M, Jalal Z. Mobile Apps to Improve Medication Adherence in Cardiovascular Disease: Systematic Review and Meta-analysis. Journal of Medical Internet Research 2021;23(5):e24190 View
  73. Sohail Arshad M, Zafar S, Yousef B, Alyassin Y, Ali R, AlAsiri A, Chang M, Ahmad Z, Ali Elkordy A, Faheem A, Pitt K. A review of emerging technologies enabling improved solid oral dosage form manufacturing and processing. Advanced Drug Delivery Reviews 2021;178:113840 View
  74. Powell R, Zaccardi F, Beebe C, Chen X, Crawford A, Cuddeback J, Gabbay R, Kissela L, Litchman M, Mehta R, Meneghini L, Pantalone K, Rajpathak S, Scribner P, Skelley J, Khunti K. Strategies for overcoming therapeutic inertia in type 2 diabetes: A systematic review and meta‐analysis. Diabetes, Obesity and Metabolism 2021;23(9):2137 View
  75. Roth C, Papassotiropoulos A, Brühl A, Lang U, Huber C. Psychiatry in the Digital Age: A Blessing or a Curse?. International Journal of Environmental Research and Public Health 2021;18(16):8302 View
  76. Nash D. Insights into the Use of Digital Tools for People with Mental Health Disorders. Population Health Management 2021;24(S2):S-53 View
  77. Skoufalos A, N'Dri L, Waters D. Leveraging Digital Medicine to Support Providers and Their Patients in Managing Serious Mental Illness. Population Health Management 2021;24(S2):S-55 View
  78. Cummins G. Smart pills for gastrointestinal diagnostics and therapy. Advanced Drug Delivery Reviews 2021;177:113931 View
  79. Walton K, Herrmann E. Medication adherence in tobacco cessation clinical trials. Addiction Neuroscience 2023;6:100069 View
  80. Litvinova O, Klager E, Yeung A, Tzvetkov N, Kimberger O, Kletecka-Pulker M, Willschke H, Atanasov A. Bibliometric analysis and evidence of clinical efficacy and safety of digital pills. Frontiers in Pharmacology 2023;14 View
  81. Mini G, Sathish T, Sarma P, Thankappan K. Effectiveness of a School‐Based Educational Intervention to Improve Hypertension Control Among Schoolteachers: A Cluster‐Randomized Controlled Trial. Journal of the American Heart Association 2022;11(2) View
  82. Khanijahani A, Akinci N, Quitiquit E. A Systematic Review of the Role of Telemedicine in Blood Pressure Control: Focus on Patient Engagement. Current Hypertension Reports 2022;24(7):247 View
  83. Chai P, Vaz C, Goodman G, Albrechta H, Huang H, Rosen R, Boyer E, Mayer K, O’Cleirigh C. Ingestible electronic sensors to measure instantaneous medication adherence: A narrative review. DIGITAL HEALTH 2022;8:205520762210831 View
  84. Castillo A, Davis A, Fischhoff B, Krishnamurti T. Digital medicines for adherence support: A conceptual framework and qualitative study of adherence among chronically ill patients. Health Informatics Journal 2021;27(5):146045822110594 View
  85. Mukherjee S, Suleman S, Pilloton R, Narang J, Rani K. State of the Art in Smart Portable, Wearable, Ingestible and Implantable Devices for Health Status Monitoring and Disease Management. Sensors 2022;22(11):4228 View
  86. Price J, Santos H, Bueno A. The effectiveness of automated digital health solutions at successfully managing obesity and obesity-associated disorders: A PICO-structured investigation. DIGITAL HEALTH 2022;8:205520762210913 View
  87. Hall A, Boring R, Miyake T. Cognitive Aging as a Human Factor: Effects of Age on Human Performance. Nuclear Technology 2023;209(3):261 View
  88. Tekale S, Varma A, Tekale S, Kumbhare U. A Review on Newer Interventions for the Prevention of Diabetic Foot Disease. Cureus 2022 View
  89. Stevens S, Gallagher S, Andrews T, Ashall-Payne L, Humphreys L, Leigh S. The effectiveness of digital health technologies for patients with diabetes mellitus: A systematic review. Frontiers in Clinical Diabetes and Healthcare 2022;3 View
  90. Guo C, Ashrafian H, Ghafur S, Fontana G, Gardner C, Prime M. Challenges for the evaluation of digital health solutions—A call for innovative evidence generation approaches. npj Digital Medicine 2020;3(1) View
  91. Hernandez M, Rodriguez F. Health Techequity: Opportunities for Digital Health Innovations to Improve Equity and Diversity in Cardiovascular Care. Current Cardiovascular Risk Reports 2023;17(1):1 View
  92. Hamrahian S, Maarouf O, Fülöp T. A Critical Review of Medication Adherence in Hypertension: Barriers and Facilitators Clinicians Should Consider. Patient Preference and Adherence 2022;Volume 16:2749 View
  93. Hamasaki H. Efficacy of Wearable Devices to Measure and Promote Physical Activity in the Management of Diabetes. EMJ Diabetes 2018:62 View
  94. Kumar K, Loebinger M, Ghafur S. The role of wirelessly observed therapy in improving treatment adherence. Future Healthcare Journal 2022;9(2):179 View
  95. Saigí-Rubió F, Borges do Nascimento I, Robles N, Ivanovska K, Katz C, Azzopardi-Muscat N, Novillo Ortiz D. The Current Status of Telemedicine Technology Use Across the World Health Organization European Region: An Overview of Systematic Reviews. Journal of Medical Internet Research 2022;24(10):e40877 View
  96. Ionov M, Konradi A. Telehealth in hypertensive patients: to whom, how and for how long?. "Arterial’naya Gipertenziya" ("Arterial Hypertension") 2022;28(2):108 View
  97. Lewinski A, Jazowski S, Goldstein K, Whitney C, Bosworth H, Zullig L. Intensifying approaches to address clinical inertia among cardiovascular disease risk factors: A narrative review. Patient Education and Counseling 2022;105(12):3381 View
  98. Jaén-Extremera J, Afanador-Restrepo D, Rivas-Campo Y, Gómez-Rodas A, Aibar-Almazán A, Hita-Contreras F, Carcelén-Fraile M, Castellote-Caballero Y, Ortiz-Quesada R. Effectiveness of Telemedicine for Reducing Cardiovascular Risk: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine 2023;12(3):841 View
  99. Herold M. Digitisation of the Health Sector: Analysis of the Digital Competences of Physicians. Open Conference Proceedings 2022;2:9 View
  100. Cucciniello M, Petracca F, Ciani O, Tarricone R. Development features and study characteristics of mobile health apps in the management of chronic conditions: a systematic review of randomised trials. npj Digital Medicine 2021;4(1) View
  101. Fundoiano-Hershcovitz ‪, Bacher D, Ritholz M, Horwitz D, Manejwala O, Goldstein P. Blood Pressure Monitoring as a Digital Health Tool for Improving Diabetes Clinical Outcomes: Retrospective Real-world Study. Journal of Medical Internet Research 2022;24(2):e32923 View
  102. Dalal J, Kerkar P, Guha S, Dasbiswas A, Sawhney J, Natarajan S, Maddury S, Kumar A, Chandra N, Suryaprakash G, Thomas J, Juvale N, Sathe S, Khan A, Bansal S, Kumar V, Reddi R. Therapeutic adherence in hypertension: Current evidence and expert opinion from India. Indian Heart Journal 2021;73(6):667 View
  103. Litvinova O, Klager E, Tzvetkov N, Kimberger O, Kletecka-Pulker M, Willschke H, Atanasov A. Digital Pills with Ingestible Sensors: Patent Landscape Analysis. Pharmaceuticals 2022;15(8):1025 View
  104. Aungst T. Reevaluating medication adherence in the era of digital health. Expert Review of Medical Devices 2021;18(sup1):25 View
  105. Mattison G, Canfell O, Forrester D, Dobbins C, Smith D, Töyräs J, Sullivan C. The Influence of Wearables on Health Care Outcomes in Chronic Disease: Systematic Review. Journal of Medical Internet Research 2022;24(7):e36690 View
  106. Cochran J, Fang H, Sonnenberg J, Cohen E, Lindenmayer J, Reuteman-Fowler J. Healthcare Provider Engagement with a Novel Dashboard for Tracking Medication Ingestion: Impact on Treatment Decisions and Clinical Assessments for Adults with Schizophrenia. Neuropsychiatric Disease and Treatment 2022;Volume 18:1521 View
  107. Liu H, Wang Y, Huang Y, Xiong D, Shen J, Siqueiros L, Bala V, Savage G, Guerrero M, Corado K, Rosen M, Fletcher C, Daar E. Ingestible sensor system for measuring, monitoring and enhancing adherence to antiretroviral therapy: An open-label, usual care-controlled, randomised trial. eBioMedicine 2022;86:104330 View
  108. Chai P, Mohamed Y, Goodman G, Bustamante M, Sullivan M, Najarro J, Mendez L, Mayer K, Boyer E, O’Cleirigh C, Rosen R. Development of a digital pill and respondent behavioral intervention (PrEPSteps) for HIV pre-exposure prophylaxis adherence among stimulant using men who have sex with men. Translational Behavioral Medicine 2022;12(1) View
  109. Nkhoma D, Soko C, Bowrin P, Manga Y, Greenfield D, Househ M, Li (Jack) Y, Iqbal U. Digital interventions self-management education for type 1 and 2 diabetes: A systematic review and meta-analysis. Computer Methods and Programs in Biomedicine 2021;210:106370 View
  110. Luo J, Zhang K, Xu Y, Tao Y, Zhang Q. Effectiveness of Wearable Device-based Intervention on Glycemic Control in Patients with Type 2 Diabetes: A System Review and Meta-Analysis. Journal of Medical Systems 2022;46(1) View
  111. Chevance A, Fortel A, Jouannin A, Denis F, Mamzer M, Ravaud P, Sidorkiewicz S. Acceptability of and Willingness to Take Digital Pills by Patients, the Public, and Health Care Professionals: Qualitative Content Analysis of a Large Online Survey. Journal of Medical Internet Research 2022;24(2):e25597 View
  112. Egilman A, Ross J. Digital medicine systems: an evergreening strategy or an advance in medication management?. BMJ Evidence-Based Medicine 2019;24(6):203 View
  113. Adje Y, Brooks K, Castillo-Mancilla J, Wyles D, Anderson P, Kiser J. The use of technology-based adherence monitoring in the treatment of hepatitis C virus. Therapeutic Advances in Infectious Disease 2022;9:204993612210956 View
  114. Gonzales S, Okusaga O, Reuteman-Fowler J, Oakes M, Brown J, Moore S, Lewinski A, Rodriguez C, Moncayo N, Smith V, Malone S, List J, Cho R, Jeffreys A, Bosworth H. Digital Medicine System in Veterans With Severe Mental Illness: Feasibility and Acceptability Study. JMIR Formative Research 2022;6(12):e34893 View
  115. Moschonis G, Siopis G, Jung J, Eweka E, Willems R, Kwasnicka D, Asare B, Kodithuwakku V, Verhaeghe N, Vedanthan R, Annemans L, Oldenburg B, Manios Y, Gong E, Votis K, Segkouli S, Triantafyllidis A, Kyparissis O, Paliokas I, Polychroniou E, De Craemer D, Anastasiou K, Tserpes K, Mavrogianni C, Karaglani E, Kalogerakou E, Maragkoudaki M, Ntzouvani A, Kontochristopoulou K, Dupont S, Dupont E, Dauzon L, Roskams M, Lennox-Chhugani N, Perrin M, Day N, Ferrer G, Snook O, Aldasoro E, Gil-Salmerón A, Peiró P, Curran D, Lyne F, Curreri N, Moschonis G, Pierantozzi N, D'Antonio C, Vespasiani G, Almonti T, Skouteris H, Taylor T, Savaglio M, Makrilakis K, Stergiou G, Liatis S, Karamanakos G, Koliaki C, Kollias A, Zikou E, Dimosthenopoulos H, Huang K, Adhikari S, Qian K, Dickhaus J, Carney K, Sahito F, Pavlovic D, Djokic D, Sahito A, Battalova G, Seghieri C, Nutti S, Vanieri M, Belle N, Bertarelli G, Cantarelli P, Ferre F, Noci A, Tortu C, Bozzi N, Ferrari D, Borelli R, Iotova V, Yotov Y, Usheva N, Kozhuharova A, Russeva V, Marinova V, Koleva S, Atanasova V, Stefanova T, Tsochev K, Aznar L, Botaya R, Lozano G, De Miguel-Etayo P, Gonzalez-Gil E, Miguel-Berges M, Pérez S, Blázquez B, Giménez-Legarre N, Toti F, Prifti S, Bombaj B, Doracaj D, Laze O, Lapardhaja A, Bruka L. Effectiveness, reach, uptake, and feasibility of digital health interventions for adults with type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials. The Lancet Digital Health 2023;5(3):e125 View
  116. Siopis G, Moschonis G, Eweka E, Jung J, Kwasnicka D, Asare B, Kodithuwakku V, Willems R, Verhaeghe N, Annemans L, Vedanthan R, Oldenburg B, Manios Y, Gong E, Votis K, Segkouli S, Triantafyllidis A, Kyparissis O, Paliokas I, Polychroniou E, De Craemer D, Anastasiou K, Tserpes K, Mavrogianni C, Karaglani E, Kalogerakou E, Maragkoudaki M, Ntzouvani A, Kontochristopoulou K, Dupont S, Dupont E, Dauzon L, Roskams M, Lennox-Chhugani N, Perrin M, Day N, Ferrer G, Snook O, Aldasoro E, Gil-Salmerón A, Peiró P, Curran D, Lyne F, Curreri N, Siopis G, Pierantozzi N, D'Antonio C, Vespasiani G, Almonti T, Skouteris H, Taylor T, Savaglio M, Makrilakis K, Stergiou G, Liatis S, Karamanakos G, Koliaki C, Kollias A, Zikou E, Dimosthenopoulos H, Huang K, Adhikari S, Qian K, Dickhaus J, Carney K, Sahito F, Pavlovic D, Djokic D, Sahito A, Battalova G, Seghieri C, Nutti S, Vanieri M, Belle N, Bertarelli G, Cantarelli P, Ferre F, Noci A, Tortu C, Bozzi N, Ferrari D, Borelli R, Iotova V, Yotov Y, Usheva N, Kozhuharova A, Russeva V, Marinova V, Koleva S, Atanasova V, Stefanova T, Tsochev K, Aznar L, Botaya R, Lozano G, De Miguel-Etayo P, Gonzalez-Gil E, Miguel-Berges M, Pérez S, Blázquez B, Giménez-Legarre N, Toti F, Prifti S, Bombaj B, Doracaj D, Laze O, Lapardhaja A, Bruka L. Effectiveness, reach, uptake, and feasibility of digital health interventions for adults with hypertension: a systematic review and meta-analysis of randomised controlled trials. The Lancet Digital Health 2023;5(3):e144 View
  117. Rudayni H, Shemy M, Aladwani M, Alneghery L, Abu-Taweel G, Allam A, Abukhadra M, Bellucci S. Synthesis and Biological Activity Evaluations of Green ZnO-Decorated Acid-Activated Bentonite-Mediated Curcumin Extract (ZnO@CU/BE) as Antioxidant and Antidiabetic Agents. Journal of Functional Biomaterials 2023;14(4):198 View
  118. Chib A, Lin S, Li C. Wearables for Health Promotion: An Interdisciplinary Review. SSRN Electronic Journal 2022 View
  119. Baral N, Volgman A, Seri A, Chelikani V, Isa S, Javvadi S, Paul T, Mitchell J. Adding Pharmacist-Led Home Blood Pressure Telemonitoring to Usual Care for Blood Pressure Control: A Systematic Review and Meta-Analysis. The American Journal of Cardiology 2023;203:161 View
  120. De Luca V, Bozzetto L, Giglio C, Tramontano G, De Simone G, Luciano A, Lucibelli L, Maffettone A, Riccio M, Romano G, Rossi E, Chiatti C, Berler A, Iaccarino G, Illario M, Annuzzi G. Clinical outcomes of a digitally supported approach for self-management of type 2 diabetes mellitus. Frontiers in Public Health 2023;11 View
  121. Biersteker T, Boogers M, Schalij M, Braun J, Groenwold R, Atsma D, Treskes R. Mobile health for cardiovascular risk management after cardiac surgery: results of a sub-analysis of The Box 2.0 study. European Heart Journal - Digital Health 2023;4(4):347 View
  122. Wu Y, Min H, Li M, Shi Y, Ma A, Han Y, Gan Y, Guo X, Sun X. Effect of Artificial Intelligence-based Health Education Accurately Linking System (AI-HEALS) for Type 2 diabetes self-management: protocol for a mixed-methods study. BMC Public Health 2023;23(1) View
  123. Mancia G, Cappuccio F, Burnier M, Coca A, Persu A, Borghi C, Kreutz R, Sanner B. Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension. Journal of Internal Medicine 2023;294(3):251 View
  124. Correia E. Lifestyle Medicine Interventions to Manage Hypertension in Brazilian Patients With Type 2 Diabetes. American Journal of Lifestyle Medicine 2023 View
  125. Chong C, Bakry M, Hatah E, Mohd Tahir N, Mustafa N. Effects of mobile apps intervention on medication adherence and type 2 diabetes mellitus control: A systematic review and meta-analysis. Journal of Telemedicine and Telecare 2023:1357633X2311749 View
  126. Bakema R, Smirnova D, Biri D, Kocks J, Postma M, de Jong L. The Use of eHealth for Pharmacotherapy Management With Patients With Respiratory Disease, Cardiovascular Disease, or Diabetes: Scoping Review. Journal of Medical Internet Research 2023;25:e42474 View
  127. Konnyu K, Yogasingam S, Lépine J, Sullivan K, Alabousi M, Edwards A, Hillmer M, Karunananthan S, Lavis J, Linklater S, Manns B, Moher D, Mortazhejri S, Nazarali S, Paprica P, Ramsay T, Ryan P, Sargious P, Shojania K, Straus S, Tonelli M, Tricco A, Vachon B, Yu C, Zahradnik M, Trikalinos T, Grimshaw J, Ivers N. Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes. Cochrane Database of Systematic Reviews 2023;2023(6) View
  128. Chiaranai C, Chularee S, Saokaew S, Bhatarasakoon P, Umnuaypornlert A, Chaomuang N, Doommai N, Nimkuntod P. Effectiveness of telehealth on the glycemic control of patients with type 2 diabetes mellitus during the COVID-19 pandemic: A systematic review and meta-analysis of randomised controlled trials. International Journal of Nursing Studies Advances 2024;6:100169 View
  129. Vyas A, Bhargava T, Saraf S, Jain V, Dubey D. A Review on digital medicine and its implications in drug development process. Asian Journal of Pharmacy and Technology 2023:263 View
  130. Fadl Elmula F, Mariampillai J, Heimark S, Kjeldsen S, Burnier M. Medical Measures in Hypertensives Considered Resistant. American Journal of Hypertension 2024;37(5):307 View
  131. Katz M, Mszar R, Grimshaw A, Gunderson C, Onuma O, Lu Y, Spatz E. Digital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities. JAMA Network Open 2024;7(2):e2356070 View
  132. Ukoaka B, Ugwuanyi E, Ukueku K, Ajah K, Udam N, Daniel F, Wali T, Gbuchie M. Digital tools for improving antiretroviral adherence among people living with HIV in Africa. Journal of Medicine, Surgery, and Public Health 2024;2:100077 View
  133. Tarricone R, Petracca F, Svae L, Cucciniello M, Ciani O. Which behaviour change techniques work best for diabetes self-management mobile apps? Results from a systematic review and meta-analysis of randomised controlled trials. eBioMedicine 2024;103:105091 View
  134. Fundoiano-Hershcovitz ‪, Ritholz M, Horwitz D, Behar E, Manejwala O, Goldstein P. The Impact of Digital Self-Monitoring of Weight on Improving Diabetes Clinical Outcomes: Quasi-Randomized Study. Journal of Medical Internet Research 2024;26:e54940 View
  135. Bersch-Ferreira A, Machado R, de Oliveira J, Santos R, da Silva L, Mota L, Pagano R, Sady E, Miyada D, Valeis N, Martins P, de Almeida J, Marchioni D, Lara E, Gherardi-Donato E, Quinhoneiro D, Carvalho A, Machado M, Gedda L, Ferro C, Carvalho A, Feoli A, Walker M, Pinto S, Silva K, Bruscato N, Moriguchi E, Penafort A, Santiago R, Osório D, Rower H, Barbosa M, da Silva J, Weber B, Cavalcanti A, Marcadenti A. Effectiveness of a two-component nutritional strategy for blood pressure control in individuals with hypertension users of a public health system: a randomized controlled clinical trial. Journal of Hypertension 2024;42(7):1173 View
  136. Browne S, Umlauf A, Moore D, Benson C, Vaida F. User Experience of Persons Using Ingestible Sensor–Enabled Pre-Exposure Prophylaxis to Prevent HIV Infection: Cross-Sectional Survey Study. JMIR mHealth and uHealth 2024;12:e53596 View
  137. Burnier M. Physician and patient adherence in hypertension trials: a point of view on an important issue to resolve. Expert Review of Pharmacoeconomics & Outcomes Research 2024;24(6):749 View
  138. Yap H, Lim J, Tan S, Ang C. Effectiveness of digital health interventions on adherence and control of hypertension: a systematic review and meta-analysis. Journal of Hypertension 2024 View

Books/Policy Documents

  1. Virdi N. Drug Adherence in Hypertension and Cardiovascular Protection. View
  2. Halilaj I, van Wijk Y, Jochems A, Lambin P. Artificial Intelligence in Medicine. View
  3. Levin-Zamir D, Parial L. Encyclopedia of Gerontology and Population Aging. View
  4. Chong W, Gu D. Encyclopedia of Gerontology and Population Aging. View
  5. Chong W, Gu D. Encyclopedia of Gerontology and Population Aging. View
  6. Yang Q, Jin W, Lu T, Liu S, Yin J, Zhou T, Ren T. Miniaturized Biosensing Devices. View
  7. Chong W, Gu D. Encyclopedia of Gerontology and Population Aging. View
  8. Levin-Zamir D, Parial L. Encyclopedia of Gerontology and Population Aging. View
  9. Hussain R, Zainal H, Mohamed Noor D, Shakeel S. Encyclopedia of Evidence in Pharmaceutical Public Health and Health Services Research in Pharmacy. View
  10. Hussain R, Zainal H, Mohamed Noor D, Shakeel S. Encyclopedia of Evidence in Pharmaceutical Public Health and Health Services Research in Pharmacy. View