The Sexunzipped Trial: Optimizing the Design of Online Randomized Controlled Trials

Julia V Bailey   ¹ , BSc, MBBS, MSc, PhD ;   Menelaos Pavlou   ² , BSc, MSc, PhD ;   Andrew Copas   ³ , MSc, PhD ;   Ona McCarthy   ⁴ , BA(Hons), MSc ;   Ken Carswell   ⁵ , BA(Hons), Mphil, DClinPsy ;   Greta Rait   ⁶ , MB ChB, Research MD, FHEA, MRCGP ;   Graham Hart   ⁷ , BA(Hons), FMedSci, PhD ;   Irwin Nazareth   ⁶ , MBBS, LRCP, FRCGP, PhD ;   Caroline Free   ⁴ , MBChB, MRCGP, PhD ;   Rebecca French   ⁴ , MSc, PhD ;   Elizabeth Murray   ^{1 †} , FRCGP, FRCP (Edin), PhD

¹ e-Health Unit, Research Department of Primary Care and Population Health, University College London, London, United Kingdom

² Department of Statistical Science, University College London, London, United Kingdom

³ Department of Infection and Population Health, University College London, London, United Kingdom

⁴ London School of Hygiene and Tropical Medicine, London, United Kingdom

⁵ Queen Mary, University of London, London, United Kingdom

⁶ PRIMENT Clinical Trials Unit, Research Department of Primary Care and Population Health, University College London, London, United Kingdom

⁷ Faculty of Population Health Sciences, University College London, London, United Kingdom

†deceased