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Skip search results from other journals and go to results- 2 JMIR Research Protocols
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In the past 2 decades, central nervous system (CNS) stimulants such as methylphenidate (MPH) have been reported to improve motor performance when used in children with attention-deficit/hyperactivity disorder (ADHD) [26,27].
JMIR Res Protoc 2024;13:e53728
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Therefore, methylphenidate has a potential risk of abuse. As it is a Schedule II substance, methylphenidate abuse can cause severe psychological or physical dependence. According to the National Survey on Drug Use and Health in the United States, 913,000 people aged >12 years abused methylphenidate in 2017. Moreover, 6.5% of the population aged between 18 and 25 years abused methylphenidate and amphetamine in 2018. The reason for methylphenidate abuse was to enhance focus while studying [12].
J Med Internet Res 2023;25:e45146
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Twitter Analysis of the Nonmedical Use and Side Effects of Methylphenidate: Machine Learning Study
Methylphenidate is a stimulant that is widely used for treating attention deficit hyperactivity disorder (ADHD) [1]. It was approved for use in children and adolescents, and recently for adult ADHD, in several countries including the United States [2]. The use of methylphenidate is increasing worldwide [3]. Although methylphenidate is considered safe to use when taken as prescribed, it does have the potential for abuse because of its focus-enhancing, appetite-reducing, and euphoric effects [4,5].
J Med Internet Res 2020;22(2):e16466
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Symptomatic Treatment of Vascular Cognitive Impairment (STREAM-VCI): Protocol for a Cross-Over Trial
Executive functioning might be improved by increasing norepinephrine and dopamine transmitters with methylphenidate. This drug can increase the concentrations of dopamine and norepinephrine in the synaptic cleft [15-17]. Two previous studies have shown a slight improvement on cognition, based on Mini-Mental State Examination (MMSE) scores, in people with dementia following methylphenidate use [18,19].
JMIR Res Protoc 2018;7(3):e80
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