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Evaluating the Onset, Severity, and Recovery of Changes to Smell and Taste Associated With COVID-19 Infection in a Singaporean Population (the COVOSMIA-19 Trial): Protocol for a Prospective Case-Control Study

Evaluating the Onset, Severity, and Recovery of Changes to Smell and Taste Associated With COVID-19 Infection in a Singaporean Population (the COVOSMIA-19 Trial): Protocol for a Prospective Case-Control Study

Importantly, the loss of smell and/or taste occurs early during COVID-19 infection, often before the onset of more established symptoms [8,17-20], and this loss may be an important marker of infection. This finding has prompted many global public health bodies to recommend that individuals who experience sudden changes in sensory acuity should self-isolate and present for diagnostic testing [2-4,21-24].

Florence Sheen, Vicki Tan, Sumanto Haldar, Sharmila Sengupta, David Allen, Jyoti Somani, Hui Yee Chen, Paul Tambyah, Ciaran G Forde

JMIR Res Protoc 2020;9(12):e24797