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Chronic ankle instability (CAI) is a condition characterized by a recurring giving way of the lateral side of the ankle and usually develops after repeated ankle sprains [1]. The indicators of CAI include mechanical instability, perceived instability, and recurrent sprain, which can occur independently or in combination [1]. In children, CAI has been reported in those with a history of ankle sprains or a high BMI and in youth athletes (eg, soccer players and dancers) [2-4].
JMIR Serious Games 2023;11:e51073
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Bowen et al [33] recently aggregated 4 studies to examine the differences in mood instability between depressed and nondepressed individuals. Participants completed daily mood diary ratings of negative and positive mood upon awakening and before bedtime for 1 week. Depressed individuals experienced greater negative mood instability over the course of the week compared with nondepressed individuals.
J Med Internet Res 2018;20(5):e168
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