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Clinical Efficacy of Multimodal Exercise Telerehabilitation Based on AI for Chronic Nonspecific Low Back Pain: Randomized Controlled Trial

Clinical Efficacy of Multimodal Exercise Telerehabilitation Based on AI for Chronic Nonspecific Low Back Pain: Randomized Controlled Trial

In exercise therapy, the combination of flexibility and strength training (the basic composition of multimodal exercise) has been shown to be the most effective intervention for people with CLBP [11,12]. Exercise therapy can be practiced in medical institutions or at home. However, due to insufficient resources, it is difficult to carry out exercise therapy in medical institutions on a large scale.

Chongwu Xiao, Yijin Zhao, Gege Li, Zhuodong Zhang, Siyu Liu, Weichao Fan, Jinjing Hu, Qiuru Yao, Chengduan Yang, Jihua Zou, Qing Zeng, Guozhi Huang

JMIR Mhealth Uhealth 2025;13:e56176

Testing an Innovative Gait Training Program in Immersive Virtual Reality for Healthy Older Adults: Protocol for a Randomized Controlled Trial

Testing an Innovative Gait Training Program in Immersive Virtual Reality for Healthy Older Adults: Protocol for a Randomized Controlled Trial

Each training session will consist of a warm-up period (10 min), main exercise (45 min), and cool-down period (5 min). Participants will adapt their locomotion to uneven terrain. They will negotiate natural obstacles such as avoiding a rock or crossing over a tree root, thus improving their gait adaptability capacities. Sessions will be provided by a coach from a multisport club proposing programs of physical activity adapted to older adults.

Nicolas Mascret, Lisa Delbes, Cédric Goulon, Gilles Montagne

JMIR Res Protoc 2025;14:e57866

Effects of Mobile Health Care App "Asmile" on Physical Activity of 80,689 Users in Osaka Prefecture, Japan: Longitudinal Observational Study

Effects of Mobile Health Care App "Asmile" on Physical Activity of 80,689 Users in Osaka Prefecture, Japan: Longitudinal Observational Study

Lifestyle-related diseases, such as cancer, heart disease, stroke, diabetes, and hypertension, are influenced by daily eating and exercise habits, which contribute to their onset and progression [1-6]. Maintaining a healthy lifestyle is essential for preventing these diseases. Several studies have reported that increasing step counts and physical activity improve mortality risk, cardiovascular disease, and dementia [7,8]. However, improving and maintaining a healthy lifestyle is difficult.

Asuka Oyama, Kenshiro Taguchi, Hiroe Seto, Reiko Kanaya, Jun'ichi Kotoku, Miyae Yamakawa, Hiroshi Toki, Ryohei Yamamoto

J Med Internet Res 2025;27:e65943

Wearable Devices in Remote Cardiac Rehabilitation With and Without Weekly Online Coaching for Patients With Coronary Artery Disease: Randomized Controlled Trial

Wearable Devices in Remote Cardiac Rehabilitation With and Without Weekly Online Coaching for Patients With Coronary Artery Disease: Randomized Controlled Trial

The primary objectives of this pilot study were to evaluate the efficacy of this system in improving exercise capacity and adherence through continuous and interactive communication between health care providers and patients and to clarify the synergistic effects of OLC on the use of wearable devices. We hypothesized that the combination of wearable devices and OLC would result in greater improvements in exercise capacity and adherence than those achieved through the use of wearable devices alone.

Ryota Nishio, Tomotaka Dohi, Miho Yokoyama, Taisuke Nakade, Norihito Takahashi, Yuichi Chikata, Hirohisa Endo, Hiroki Nishiyama, Iwao Okai, Hiroshi Iwata, Shinya Okazaki, Katsumi Miyauchi, Hiroyuki Daida, Tohru Minamino

JMIR Mhealth Uhealth 2025;13:e63797

Effects of a Computer Vision–Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial

Effects of a Computer Vision–Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial

Exercise has been acknowledged as a nonpharmacological intervention modality for the treatment and prevention of musculoskeletal disorders, including osteoarthritis, osteoporosis, back pain, and rheumatoid arthritis [3]. Specifically, it has been empirically demonstrated that participating in appropriate physical exercise while being monitored by a physiotherapist effectively maintains physical health and athletic ability [4].

Dian Zhu, Jianan Zhao, Tong Wu, Beiyao Zhu, Mingxuan Wang, Ting Han

JMIR Mhealth Uhealth 2025;13:e63022

Effects of Integrating Wearable Activity Trackers With a Home-Based Multicomponent Exercise Intervention on Fall-Related Parameters and Physical Function in Older Adults: Randomized Controlled Trial

Effects of Integrating Wearable Activity Trackers With a Home-Based Multicomponent Exercise Intervention on Fall-Related Parameters and Physical Function in Older Adults: Randomized Controlled Trial

Numerous studies have demonstrated the effectiveness of exercise interventions in preventing falls and improving physical function in older adults [8,9]. Each type of exercise (ie, resistance, aerobic, and balance training) has specific benefits, and incorporating high-challenge balance training in exercise programs is particularly emphasized for fall prevention [9,10].

Yejin Kim, Kyung Hee Park, Hye-Mi Noh

JMIR Mhealth Uhealth 2025;13:e64458

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

Participants will then be randomized by an independent investigator to either exercise intervention arm A or exercise intervention and control arm B using a computer-generated random number table. After the baseline visit 1 examination, the A-arm will undergo 12 weeks of a progressive aerobic exercise intervention protocol, after which the clinical examination will be repeated.

Monika Ludlova, Kateřina Koudelková, Jitka Pallova, Barbora Koudelkova, Michaela Siklova, Monika Cahova, Tomas Vetrovsky, Michal Steffl, Jan Gojda

JMIR Res Protoc 2025;14:e67570

Multihealth Promotion Programs on Physical Health and Quality of Life in Older Adults: Quasi-Experimental Study

Multihealth Promotion Programs on Physical Health and Quality of Life in Older Adults: Quasi-Experimental Study

However, systematic reviews and meta-analyses reveal that current health promotion studies predominantly focus on single exercise modalities, yielding inconsistent effects on physical function and lacking in-depth exploration of multicomponent exercise interventions, particularly in practical applications and comprehensive outcome assessments [4,5,7].

Li-Yun Lee, Heng-Hsin Tung, George Liao, Su-Ju Liu, Zi-Yu Chen, Yea-Ru Yang

Interact J Med Res 2025;14:e65213

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

Intensity: moderate intensity exercise as indicated by a rating of perceived exertion of 5 to 7 on the Borg 0‐10 scale. Time: as many minutes of exercise as possible that could be fit within students’ school schedules (eg, either within their physical education period or a study hall or gap period). Type: VR exercise at home or in the school setting, at the choice of the caregiver and participant.

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801