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Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study

Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study

For flagged cases, members of these research teams contacted individuals to further evaluate the authenticity of attempts at study enrollment. Resnik and Mc Cann [19] have recommended that any evidence of potentially deceptive activity should result in the exclusion of the prospective participant from the study enrollment.

Krista M Kezbers, Michael C Robertson, Emily T Hébert, Audrey Montgomery, Michael S Businelle

J Med Internet Res 2025;27:e66384

Improving Participant Recruitment in Clinical Trials: Comparative Analysis of Innovative Digital Platforms

Improving Participant Recruitment in Clinical Trials: Comparative Analysis of Innovative Digital Platforms

Over the years, a face-to-face approach has been used in various stages of clinical trial research, including recruitment, consent for enrollment, retention, delivery of interventions, and data collection [8,9]. However, it has been widely observed that a significant number of individuals and patients interested in participating in a clinical trial are not adequately informed about how to identify and approach clinical trials that align with their needs and interests [10].

Alexia Georgia Bikou, Elena Deligianni, Foteini Dermiki-Gkana, Nikolaos Liappas, José Gabriel Teriús-Padrón, Maria Eugenia Beltrán Jaunsarás, Maria Fernanda Cabrera-Umpiérrez, Christos Kontogiorgis

J Med Internet Res 2024;26:e60504

Measuring Relationship Influences on Romantic Couples’ Cancer-Related Behaviors During the COVID-19 Pandemic: Protocol for a Longitudinal Online Study of Dyads and Cancer Survivors

Measuring Relationship Influences on Romantic Couples’ Cancer-Related Behaviors During the COVID-19 Pandemic: Protocol for a Longitudinal Online Study of Dyads and Cancer Survivors

Thus, this report aims to (1) detail the methodological decisions, tools, and processes that were used during the R2 C2 study, (2) report recruitment, enrollment, and response data, and (3) reflect on best practices and limitations to guide future study design. We engaged in a multipronged approach to develop the study in a way that would address the abovementioned gaps in cancer prevention research among dyads.

Jennifer M Bowers, Chloe O Huelsnitz, Laura A Dwyer, Laurel P Gibson, Tanya Agurs-Collins, Rebecca A Ferrer, Amanda M Acevedo

JMIR Res Protoc 2024;13:e48516

A/B Testing of User Enrollment Forms to Enhance Diversity in the Biomedical Workforce via the National Research Mentoring Network: User-Centered Design Case Study

A/B Testing of User Enrollment Forms to Enhance Diversity in the Biomedical Workforce via the National Research Mentoring Network: User-Centered Design Case Study

To increase enrollment, especially the enrollment of diverse users, our team sought to improve the ease and appeal of the enrollment process by using split testing (ie, A/B testing)—a method that is used widely to compare two variations of a form or content [4-9]. For web forms, this testing is accomplished by randomly serving one version of a form to half of the platform visitors and a different version to the other half.

Toufeeq Ahmed Syed, Erika L Thompson, Jason Johnson, Zainab Latif, Nan Kennedy, Damaris Javier, Katie Stinson, Jamboor K Vishwanatha

JMIR Hum Factors 2024;11:e54532

Email-Based Recruitment Into the Health eHeart Study: Cohort Analysis of Invited Eligible Patients

Email-Based Recruitment Into the Health eHeart Study: Cohort Analysis of Invited Eligible Patients

To study the success of our campaign in recruiting different segments of our target population, we evaluated our invited eligible patient cohort at the earliest point of research participation—enrollment—defined by registration and consent into the Health e Heart Study.

Madelena Y Ng, Jeffrey E Olgin, Gregory M Marcus, Courtney R Lyles, Mark J Pletcher

J Med Internet Res 2023;25:e51238

Occurrence Patterns of Traumatic Brain Injury Within the Emergency Department and Internal Screening Process Efficacy During the COVID-19 Pandemic: Retrospective Analysis

Occurrence Patterns of Traumatic Brain Injury Within the Emergency Department and Internal Screening Process Efficacy During the COVID-19 Pandemic: Retrospective Analysis

The parent study, which focuses on enrollment of pediatric TBI patients into biobanks, initially halted recruitment because in-person enrollment was critical for proper consent and biospecimen procurement; however, the research team has maintained existing digital screening efforts to identify potential participants, as described in the Methods section below.

Tapasvini Anmol Paralkar, Phoebe Lay, Sawyer Stubbs, Syed Hadi Ahmed, Minha Ghani, Nico Osier

Interact J Med Res 2022;11(1):e29513

Mobile Virtual Reality Versus Mobile 360° Video to Promote Enrollment in the Diabetes Prevention Program Among Hispanic Adults: Pilot Study

Mobile Virtual Reality Versus Mobile 360° Video to Promote Enrollment in the Diabetes Prevention Program Among Hispanic Adults: Pilot Study

Clearly, there is need for scalable interventions that increase enrollment in the DPP among Hispanic adults. Currently, most individuals with prediabetes who enroll in the DPP are identified by their primary care provider (PCP), counseled regarding the benefits of the program, and then referred. Studies of provider referrals to the DPP have reported variable DPP enrollment rates, ranging from 8% to 19% [6-8].

Bryan Smith Gibson, Sara Simonsen, Jakob D Jensen, Leah Yingling, Julia Schaefer, Vishnu Sundaresh, Yue Zhang, Roger Altizer

JMIR Diabetes 2022;7(1):e26013

General Practice and Digital Methods to Recruit Stroke Survivors to a Clinical Mobility Study: Comparative Analysis

General Practice and Digital Methods to Recruit Stroke Survivors to a Clinical Mobility Study: Comparative Analysis

Digital media and social media (SM) may provide a cost-effective approach to complementing existing recruitment issues and increase the enrollment of stroke survivors in research. The social networks Facebook and Twitter are among the most popular platforms used for research recruitment [18,19]. A smaller subset of studies has experimented with search engine marketing on Google [20-24] and other search engines, such as Yahoo and Bing, to recruit to studies [25].

Katja Reuter, Chang Liu, NamQuyen Le, Praveen Angyan, James M Finley

J Med Internet Res 2021;23(10):e28923