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Challenges and Opportunities of the Human-Centered Design Approach: Case Study Development of an Assistive Device for the Navigation of Persons With Visual Impairment

Challenges and Opportunities of the Human-Centered Design Approach: Case Study Development of an Assistive Device for the Navigation of Persons With Visual Impairment

Approximately 2 million people in Colombia live with some form of visual disability, representing over 4% of the country’s population [43,44]. In this group, more than 80% live in poverty, and illiteracy rates are 3 times higher among individuals with VI compared to the general population [45]. Colombia is a signatory country to the Convention on the Rights of Persons with Disabilities.

Mario Andres Chavarria, Luisa María Ortiz-Escobar, Bladimir Bacca-Cortes, Victor Romero-Cano, Isabella Villota, Jhon Kevin Muñoz Peña, José Roberto Londoño Sánchez, Oscar Campo, Silvan Suter, Jhon Jairo Cabrera-López, Maria Fernanda Sanchez Patiño, Eduardo Francisco Caicedo-Bravo, Michael Stein, Samia Hurst, Klaus Schönenberger, Minerva Rivas Velarde

JMIR Rehabil Assist Technol 2025;12:e70694

Simulation Through Virtual Reality for the Management of Anxiety and Neuropathic Pain: Protocol for a Randomized Clinical Study

Simulation Through Virtual Reality for the Management of Anxiety and Neuropathic Pain: Protocol for a Randomized Clinical Study

The comorbidity of chronic pain and affective disorders is closely associated with higher pain severity, greater disability, and a substantial decline in patient quality of life [4], complicating treatment significantly. Persistent long-term pain and associated suffering seem to be key factors in developing secondary affective and emotional disorders.

Jorge Muriel-Fernández, Jaime Gonçalves-Sánchez, Clemente Muriel-Villoria, Jesús María Gonçalves-Estella, José Manuel Lopez-Millán

JMIR Res Protoc 2025;14:e64781

Examination of Chronic Sorrow Among Parents of Children With Disabilities: Cross-Sectional Study

Examination of Chronic Sorrow Among Parents of Children With Disabilities: Cross-Sectional Study

Many of the participants were caring for a child with a permanent disability (n=79, 89%) and most participants had a university level of education (n=54, 61%). Most of the children had been diagnosed for less than 1 year (n=45, 51%) and Down syndrome was the most reported disability (n=39, 44%). The sample demographic characteristics (N=89). a There were 87 responses for this question (ie, 2 participants did not respond).

Samaa Al Anazi, Naseem Alhujaili, Dina Sinqali, Ftoon Al Heej, Lojain Al Somali, Samaher Khayat, Talah Ramboo

JMIR Pediatr Parent 2025;8:e65754

Effectiveness of Digital Behavioral Activation Interventions for Depression and Anxiety: Systematic Review and Meta-Analysis

Effectiveness of Digital Behavioral Activation Interventions for Depression and Anxiety: Systematic Review and Meta-Analysis

The outcomes pooled in our meta-analysis included depression symptoms, anxiety, Qo L, BA, functioning and disability, and stress. All interventions were compared to the respective control groups. Only 10 studies had sufficient data on depression symptoms for a meta-analysis.

Eric Jia, Jushawn Macon, Michelle Doering, Joanna Abraham

J Med Internet Res 2025;27:e68054

Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation

Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation

Multiple sclerosis (MS) is a leading cause of chronic neurological disability, affecting around 2.8 million people worldwide and >700,000 people in the United States, while causing high health and socioeconomic burdens [1-3]. People with MS may experience a variety of neurological symptoms involving the cognitive, motor, sensory, vision, bowel, or bladder domains, as well as symptoms of depression, fatigue, and sleep disturbance in their daily lives [4].

Zongqi Xia, Prerna Chikersal, Shruthi Venkatesh, Elizabeth Walker, Anind K Dey, Mayank Goel

J Med Internet Res 2025;27:e70871

Factors Related to Pain and Disability Outcomes After an Internet-Delivered or Physiotherapist-Led Exercise Program for Individuals With Chronic Whiplash Symptoms: Secondary Analysis of a Randomized Controlled Study

Factors Related to Pain and Disability Outcomes After an Internet-Delivered or Physiotherapist-Led Exercise Program for Individuals With Chronic Whiplash Symptoms: Secondary Analysis of a Randomized Controlled Study

Consequently, there is a need to identify factors related to improvement in disability and pain in order to optimize treatment, discriminating them from factors that may contribute to sustained problems. An earlier study found that depression, low self-efficacy, and higher disability were associated with a larger pain area in women with chronic WAD [10].

Gunnel Peterson, Stefan Ljunggren, Anneli Peolsson

JMIR Hum Factors 2025;12:e67991

Evidence of Interventions for the Prevention of Unintentional Injuries: Scoping Review

Evidence of Interventions for the Prevention of Unintentional Injuries: Scoping Review

In addition to mortality risk, unintentional injuries can result in significant disability and disruption to quality of life [2,3]. Unfortunately, over 95% of all child injury deaths occur in low- and middle-income countries, resulting in a highly inequitable burden [4]. In India alone, unintentional injuries contribute to 9.1 deaths per 100,000 population, while transport injuries account for 2.8 deaths per 100,000 population [5].

Sheela Shetty, Baby S Nayak, Anice George, Avinash Shetty, Vasudeva Guddattu

JMIR Pediatr Parent 2025;8:e67877

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

These findings are also supported by more overarching reviews of disability exercise studies outside of the school setting [2]. Children with mobility disabilities who cannot walk, run, or cycle for prolonged periods have very few evidenced aerobic exercise modalities for improving their cardiometabolic health and cardiorespiratory fitness [2,14,15]. Active video gaming is one of the few evidenced aerobic exercise modalities that can improve health among children with disabilities [14,15].

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801

Development of a Longitudinal Model for Disability Prediction in Older Adults in China: Analysis of CHARLS Data (2015-2020)

Development of a Longitudinal Model for Disability Prediction in Older Adults in China: Analysis of CHARLS Data (2015-2020)

Therefore, accurate prediction of disability is crucial for early intervention and effective management. Despite significant research efforts to forecast disability in older adults, existing models often lack sufficient precision and fail to account for the complex, multifactorial nature of disability. These models typically overlook the broader context of risk factors and offer limited utility for public health decision-making [4-6].

Jingjing Chu, Ying Li, Xinyi Wang, Qun Xu, Zherong Xu

JMIR Aging 2025;8:e66723

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

Multiple sclerosis (MS) is a chronic disease affecting the central nervous system in which those affected typically have intermittent neurologic symptoms and signs early in the course (relapsing-remitting multiple sclerosis [RRMS]) but often, subsequently (or, less commonly, from onset), slowly accumulate disability (progressive multiple sclerosis [PMS]). Currently available tools to measure disability in MS are limited.

Nicole Bou Rjeily, Muraleetharan Sanjayan, Pratim Guha Niyogi, Blake E Dewey, Alexandra Zambriczki Lee, Christy Hulett, Gabriella Dagher, Chen Hu, Rafal D Mazur, Elena M Kenney, Erin Brennan, Anna DuVal, Peter A Calabresi, Vadim Zipunnikov, Kathryn C Fitzgerald, Ellen M Mowry

JMIR Mhealth Uhealth 2025;13:e57599