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Skip search results from other journals and go to results- 323 Journal of Medical Internet Research
- 252 JMIR Mental Health
- 219 JMIR Formative Research
- 165 JMIR Research Protocols
- 64 JMIR mHealth and uHealth
- 34 JMIR Public Health and Surveillance
- 20 JMIR Human Factors
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Adolescent depression is a significant mental health crisis; 14.7% of the adolescent population reports at least one major depressive episode with severe impairment [1]. This trend predates the COVID-19 pandemic [2] and has continued apace [3]. The impact of adolescent depression is severe; a depressive episode leads to immediate debilitating effects plus long-term consequences [4], for example, impaired academic performance [5] and challenges in forming interpersonal relationships [6].
JMIR Form Res 2025;9:e66187
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The mean state depression scores pretreatment were similar in the control and treatment groups (P=.58) and represented moderate severity state depression at baseline in both groups. The mean state anxiety scores at baseline were also similar between the control and treatment groups (P=.11), however, scores represented moderate-severity state anxiety in the control group and severe state anxiety in the treatment group.
JMIR Form Res 2025;9:e66131
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Globally, depression and anxiety are two of the most prevalent mental health disorders. In 2019, an estimated 280 million people were living with a depressive disorder, while >300 million people were living with an anxiety disorder [1]. Depression and anxiety commonly co-occur, with comorbidity rates as high as 50% [2].
JMIR Hum Factors 2025;12:e69499
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The maternal depression was measured with the Edinburgh Postnatal Depression Scale [25] at baseline (gestational weeks 24-28) and again at gestational weeks 35-37. The scale consists of 10 items, each scored from 0 to 3, yielding a total score range of 0 to 30. A score of 10 or higher is commonly used as the threshold to indicate possible depression [25].
JMIR Mhealth Uhealth 2025;13:e60855
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While some centers established a depression diagnosis based on a standard depression screener (eg, the Patient Health Questionnaire 9), other patients were asked to self-report an existing depression diagnosis.
Demographic differences between patients with and without a depression diagnosis were assessed using the Welch t test and a χ2 analysis.
JMIR Diabetes 2025;10:e70380
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Depression is the foremost contributor to global disability [1]. Longitudinal studies show that symptoms of depression typically begin in a person’s 20s to early 30s [2]. In recent years, college students’ mental health has worsened, with major depression rising disproportionately within this population [3-5]. College students assessed during the COVID-19 pandemic witnessed a 300% increase in the risk of developing depressive disorders as compared to the previous 8 years [6].
JMIR Form Res 2025;9:e67964
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The following images were used (details are given in Multimedia Appendix 2): (1) a sad woman lying on the bed looking into the camera—gray theme with an orange textbox (“together against depression”); (2) a sad man sitting on the couch looking downwards—sepia theme with an orange textbox (“together against depression”); (3) a senior male physician looking into the camera with folded arms—white and blue theme with an orange textbox (“together against depression”); (4) couple 1, a couple with a woman in front
JMIR Ment Health 2025;12:e65920
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People with MS may experience a variety of neurological symptoms involving the cognitive, motor, sensory, vision, bowel, or bladder domains, as well as symptoms of depression, fatigue, and sleep disturbance in their daily lives [4]. Comprehensive MS care involves timely symptom management, but clinicians’ awareness of symptoms often lags patient experience. Frequent symptom monitoring could improve clinical care and quality of life.
J Med Internet Res 2025;27:e70871
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Persistent stress diminishes quality of life over time and is linked to a higher prevalence of mental health disorders such as depression and anxiety [3,4]. Since stress may promote the development of depression and anxiety, these disorders are also considered important risk factors for the development or worsening of cardiovascular health issues [5].
J Med Internet Res 2025;27:e67118
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The data used in this study comes from seven distinct subreddits: r/adhd, r/anxiety, r/bipolarreddit, r/bpd, r/depression, r/ptsd, and r/schizophrenia. Following the removal of posts containing text that would be revealing of the subreddit (see “Methods” section), there was a nearly 7-fold difference between the total number of posts in each subreddit.
JMIR AI 2025;4:e67369
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