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Impact of Digital Health on Patient-Provider Relationships in Respiratory Secondary Care Based on Qualitative and Quantitative Evidence: Systematic Review

Impact of Digital Health on Patient-Provider Relationships in Respiratory Secondary Care Based on Qualitative and Quantitative Evidence: Systematic Review

Trust emerged as the foundational element in the patient-provider relationship. Trust was defined as “the patient’s confidence that the physician will do what is best for the patient” [6]. Digital care could impact the other four themes (adoption factors, confidence in technology, connection, and empowerment), enhancing or diminishing trust. The clinical context significantly influenced the adoption [61].

Michaela Senek, David Drummond, Hilary Pinnock, Kjeld Hansen, Anshu Ankolekar, Úna O'Connor, Apolline Gonsard, Oleksandr Mazulov, Katherina Bernadette Sreter, Christina Thornton, Pippa Powell

J Med Internet Res 2025;27:e70970

Attitudes Toward AI Usage in Patient Health Care: Evidence From a Population Survey Vignette Experiment

Attitudes Toward AI Usage in Patient Health Care: Evidence From a Population Survey Vignette Experiment

Integrating AI technology into health care at scale requires general trust toward and acceptance of AI use in medical contexts. Consequently, a deeper understanding of potential concerns is necessary for an ethical integration of AI into health care. Thus far, empirical evidence on the factors of public trust toward AI in patient health care is limited.

Simon Kühne, Jannes Jacobsen, Nicolas Legewie, Jörg Dollmann

J Med Internet Res 2025;27:e70179

User Intent to Use DeepSeek for Health Care Purposes and Their Trust in the Large Language Model: Multinational Survey Study

User Intent to Use DeepSeek for Health Care Purposes and Their Trust in the Large Language Model: Multinational Survey Study

In addition, the framework addresses mediation pathways, where trust operates as an intermediary in 2 distinct relationships. First, the study investigates whether trust mediates the link between ease of use and intent to use, positing that user-friendly design can bolster trust, reinforcing the inclination to adopt Deep Seek.

Avishek Choudhury, Yeganeh Shahsavar, Hamid Shamszare

JMIR Hum Factors 2025;12:e72867

Users' Perceptions and Trust in AI in Direct-to-Consumer mHealth: Qualitative Interview Study

Users' Perceptions and Trust in AI in Direct-to-Consumer mHealth: Qualitative Interview Study

Empirical work assessing trust in health care provider-to-consumer conversational agents has shown that trust has interpersonal (eg, trust in companies and health care providers), social (eg, testimonies from loved ones and health care providers), and technological dimensions (eg, trust in the capabilities of the tool and design cues) [16].

Katie Ryan, Justin Hogg, Max Kasun, Jane Paik Kim

JMIR Mhealth Uhealth 2025;13:e64715

The Effectiveness of a Custom AI Chatbot for Type 2 Diabetes Mellitus Health Literacy: Development and Evaluation Study

The Effectiveness of a Custom AI Chatbot for Type 2 Diabetes Mellitus Health Literacy: Development and Evaluation Study

This focus on trust and explainability is essential for clinical use. Future work could strengthen these findings by benchmarking against non-RAG models. A lack of benchmarking with non-RAG LLMs such as Chat GPT or web searches may be seen as a possible limitation of this study. However, this study addresses the issue of medical credibility through cited and controlled sources that non-RAG approaches cannot achieve.

Anthony Kelly, Eoin Noctor, Laura Ryan, Pepijn van de Ven

J Med Internet Res 2025;27:e70131

The Impact of Trust and the Role of the Opt-Out Mechanism in Willingness to Share Health Data via Electronic Health Records in Germany: Telephone Survey Study

The Impact of Trust and the Role of the Opt-Out Mechanism in Willingness to Share Health Data via Electronic Health Records in Germany: Telephone Survey Study

On a more abstract level, it can be argued that trust plays an essential role in health in general [46] and in data sharing in particular. Since the sharing of data is a socially highly indeterminate constellation for social action, trust is a crucial resource. The risks taken by data donors as well as the potential benefits depend strongly on other actors and can hardly be known in advance.

Felix Wilke

JMIR Hum Factors 2025;12:e65718

Participant Evaluation of Blockchain-Enhanced Women’s Health Research Apps: Mixed Methods Experimental Study

Participant Evaluation of Blockchain-Enhanced Women’s Health Research Apps: Mixed Methods Experimental Study

Once recorded on a blockchain, transactions are immutable (cannot be changed or deleted), existing in a verifiable and auditable manner that fosters transparency and trust [1,3]. While blockchain is best known as the underlying technology of cryptocurrencies like Bitcoin, the application of its properties in the health research sector can transform the ways we share, access, and use data [1,4].

Madelena Y Ng, Jodi Halpern, Olivia Shane, Tina Teng, Michael Nguyễn, Casey Ryan Alt, Anaïs Barthe Leite, Sean Moss-Pultz, Courtney R Lyles, Coye Cheshire

JMIR Mhealth Uhealth 2025;13:e65747

Beliefs in Misinformation About COVID-19 and the Russian Invasion of Ukraine Are Linked: Evidence From a Nationally Representative Survey Study

Beliefs in Misinformation About COVID-19 and the Russian Invasion of Ukraine Are Linked: Evidence From a Nationally Representative Survey Study

However, it remains unknown whether users of these channels are significantly more likely to believe the misinformation and to trust specific geopolitical powers on a nationwide scale. Therefore, we examined associations between (2a) political trust and the 2 sets of misinformation, as well as associations between (2b) media use factors and the 2 sets of misinformation.

Dominika Grygarová, Marek Havlík, Petr Adámek, Jiří Horáček, Veronika Juríčková, Jaroslav Hlinka, Ladislav Kesner

JMIR Infodemiology 2025;5:e62913

Prioritizing Trust in Podiatrists’ Preference for AI in Supportive Roles Over Diagnostic Roles in Health Care: Qualitative Interview and Focus Group Study

Prioritizing Trust in Podiatrists’ Preference for AI in Supportive Roles Over Diagnostic Roles in Health Care: Qualitative Interview and Focus Group Study

The literature on trust in AI highlights concerted efforts to foster trust by exploring strategies to address trust issues between AI systems and users. For example, some studies suggest that redefining AI as a supportive adjunct to professionals rather than a standalone solution could promote acceptance [9,10]. In addition, showcasing instances where AI surpasses human experts in specific tasks may enhance humans’ trust in AI [5,9,11].

Mohammed A Tahtali, Chris C P Snijders, Corné W G M Dirne, Pascale M Le Blanc

JMIR Hum Factors 2025;12:e59010

Finding Consensus on Trust in AI in Health Care: Recommendations From a Panel of International Experts

Finding Consensus on Trust in AI in Health Care: Recommendations From a Panel of International Experts

In this paper, we focus on a central inhibitor of successful AI adoption in health care, namely, the low levels of user trust in AI systems [18]. Understanding and fostering trust in AI remains challenging, not only practically but also conceptually. Interpersonal trust constitutes a complex and contested construct in philosophy and social sciences [19-24]. Moreover, accounts diverge on what constitutes being worthy of trust, namely, on the definition of trustworthiness [19,20].

Georg Starke, Felix Gille, Alberto Termine, Yves Saint James Aquino, Ricardo Chavarriaga, Andrea Ferrario, Janna Hastings, Karin Jongsma, Philipp Kellmeyer, Bogdan Kulynych, Emily Postan, Elise Racine, Derya Sahin, Paulina Tomaszewska, Karina Vold, Jamie Webb, Alessandro Facchini, Marcello Ienca

J Med Internet Res 2025;27:e56306