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TGD populations are also subject to the factors that drive STB risk in the general population as well as the psychological and interpersonal factors that are highlighted in established theoretical models of suicidality, including the interpersonal theory of suicide [22]. Recent research has integrated these theoretical models to suggest that the intersection of minority stressors and general suicide theoretical precursors drives STB risk in TGD people [35].
J Med Internet Res 2025;27:e65452
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Adolescent depression and suicidality are part of a growing public health crisis that has been further exacerbated by the COVID-19 pandemic [1]. In 2022, 19.5% of US adolescents aged 12‐17 years experienced a major depressive episode and 13.4% reported having seriously considered suicide [2]. Pediatric societies recommend that pediatric primary care providers (PCPs) screen adolescents for both depression and suicidality [3-6].
JMIR Form Res 2025;9:e67624
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This qualitative study was conducted as part of the Center for Enhancing Treatment and Utilization for Depression and Emergent Suicidality (ETUDES Center), an ALACRITY Center funded by the National Institute of Mental Health (NIMH P50 MH115838), aimed at helping providers better support youth experiencing severe depression, suicidality, or both.
JMIR Hum Factors 2025;12:e64867
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Recent research has highlighted ML techniques, particularly foundational language models, in comprehensive suicidality prediction [38,39] and extraction of relevant textual indicators [40,41]. Transformer-based models outperform traditional ML approaches in suicide prediction using textual data, especially in social media datasets [38,42-45], though their real-world clinical applicability has remained unexplored.
The clinical implementation of ML models requires rigorous validation [46].
JMIR Public Health Surveill 2025;11:e63809
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Encouraging meta-analyses suggest that TMS may also effectively treat suicidality [71,72]. For example, a randomized controlled trial (RCT) reported a 44% decrease in individuals experiencing “thoughts of suicide” after high-dose left-sided DLPFC TMS treatment [73]. In addition, a study of pooled sham-controlled trials reported that bilateral TMS is associated with a decline in SI [74].
JMIR Res Protoc 2024;13:e58206
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Addressing knowledge gaps regarding the burden of suicidality among youth with CPI-MIND comorbidity and determinants and outcomes associated with suicidality, as well as use of psychiatric services, is desperately needed to inform the provision of timely and appropriate health services to reduce the incidence of suicidality in this vulnerable group. To do this, we need robust contemporary epidemiological data on a representative sample of youth.
JMIR Res Protoc 2024;13:e57103
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This study aimed to develop an ML model to predict suicidality in Korean adolescents aged 13 to 18 years using clinical features extracted from 2 large independent data sets: the Korea Youth Risk Behavior Web-based Survey (KYRBS) and the Korea National Health and Nutrition Examination Survey (KNHANES) [19,20]. Figure 1 shows the workflow diagrams of the KYRBS and KNHANES data sets, which both offer nationally representative samples and estimates of the total adolescent population in South Korea.
J Med Internet Res 2024;26:e51473
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Thoughts of death or suicide, planning or preparing suicide, attempting suicide, and completing suicide are defined as suicidality [1]. Although suicidal thoughts, plans, and attempts are common, completed suicide is rare. Suicidality is a symptom often found in patients experiencing mental disorder [2].
JMIR Res Protoc 2023;12:e45438
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Due to the abovementioned differences, EC and CC may influence youth NSSI and suicidality differently.
JMIR Public Health Surveill 2023;9:e47058
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