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To alleviate this debilitating impact, psychosocial interventions reducing self-stigma in persons with chronic skin disease are urgently needed. Systematic reviews by Topp et al [7] and Traxler et al [8] reported that most interventions including counseling, self-help, social skills training, and cognitive behavioral therapy (CBT), generally had positive effects on self-stigma and related constructs.
JMIR Form Res 2025;9:e70290
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However, stigma, lack of awareness, and missing linkages between testing and treatment services remain significant challenges to advancing the End of AIDS agenda. Additionally, the lack of data on key indicators, such as viral suppression rates among high-risk groups, makes it difficult to design effective health programs that address the specific needs of populations affected by the HIV epidemic in the country [6].
JMIR Res Protoc 2025;14:e58252
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Stigma Attitudes Toward HIV/AIDS From 2011 Through 2023 in Japan: Retrospective Study in Japan
In health care settings, stigma decreases medication adherence and reduces trust in health care practitioners (HCPs) among those experiencing HIV stigma [10]. The effects of HIV stigma are not limited to health care behaviors or social interaction but also contribute to an overall poor quality of life [11-13].
J Med Internet Res 2025;27:e69696
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Interventions that have been studied use didactics to increase awareness about the need to reduce stigma and increase compassion [20]. However, these interventions do not reflect the overwhelming evidence that education alone is not sufficient to change practice behavior [21,22] and that stigmatized attitudes may prevent the application of education to individual practice [23].
JMIR Hum Factors 2025;12:e67685
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The impact of self-stigma on DMHI engagement was apparent among Chinese participants. For example, one participant thought DMHIs were unnecessary because HCPs should be able to address their own problems (quote 28 in Multimedia Appendix 2). Other participants displayed similar attitudes and associated personal and professional virtues with mental well-being (quotes 30 and 31 in Multimedia Appendix 2).
JMIR Ment Health 2025;12:e67190
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Given the salience of stigma in substance use recovery, posts were eligible if they contained keywords suggesting that stigma might be present, including adjectives that are highly indicative of stigma (eg, “shame,” “untrustworthy,” and “disappoint”), pejorative labels (eg, “crackhead,” “junkie,” and “alcoholic”), and references to persons who might be involved in stigma-related experiences (eg, partners, parents, and coworkers).
JMIR Form Res 2025;9:e57468
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In many cultures, including South Korea (hereafter referred to as Korea), unmarried women grapple with the stigma surrounding sexual and reproductive health (SRH), often opting to suffer in silence rather than seek necessary care [1-6]. Conversations about SRH topics—such as contraception, menstruation, sexual discomfort, or sexual pleasure—remain taboo, hindering access to essential services, such as screening and prevention of sexually transmitted infections (STIs) [3,7].
J Med Internet Res 2025;27:e62716
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Promises and Pitfalls of Internet Search Data in Mental Health: Critical Review
Perceived risk related to stigma and adherence to digital mental health initiatives are also important considerations.
Fourth, existing studies have been limited by small sample sizes—typically 100 participants or fewer. However, for accurate detection of psychopathology, language models must be highly complex and training of such models requires thousands of observations [46]. Moreover, model generalizability must be evaluated using new sample populations.
JMIR Ment Health 2025;12:e60754
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In both samples, there was a greater overall preference for in-person than digital treatment, but there was a significantly greater preference for digital treatment for those with higher levels of help-seeking self-stigma [18]. Greater preferences for digital treatment options have also been found for select groups, such as first-year college students [19].
J Med Internet Res 2025;27:e54608
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In turn, attitude and empathy levels can also be influenced by the level of stigma [7]. Stigma has been commonly associated with psychotic disorders [8]. Some negative perceptions of individuals with psychotic disorders included inaccurate and pejorative labels such as “unpredictable,” “violent,” and “aggressive,” even by health care workers [9,10]. Thus, stigma potentially prevents individuals who experience psychotic disorders from seeking help, as they fear discrimination [1].
JMIR Ment Health 2025;12:e66925
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