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Effect of Medication Management at Home via Pharmacist-Led Home Televisits: Protocol for a Cluster Randomized Controlled Trial

Effect of Medication Management at Home via Pharmacist-Led Home Televisits: Protocol for a Cluster Randomized Controlled Trial

In particular, older adults are more susceptible to ADRs due to the changes in their physiology, clearance, and reserves [11], particularly with polypharmacy [9,12] Based on the phycological changes in the older population, knowing the drug regimens with older adults is an important feature in order to provide medication safety and make adjustment to their regimen accordingly to ensure appropriate medication use.

Sheikh Rubana Hossain, Akanksha N Samant, Briana C Balsamo, Chelsea E Hawley, Michael C Zanchelli, Carolyn Zhu, Maria D Venegas, Marina Robertson, Megan B McCullough, Judith L Beizer, Kenneth S Boockvar, Albert L Siu, Lauren R Moo, William W Hung

JMIR Res Protoc 2025;14:e65141

ChatGPT’s Attitude, Knowledge, and Clinical Application in Geriatrics Practice and Education: Exploratory Observational Study

ChatGPT’s Attitude, Knowledge, and Clinical Application in Geriatrics Practice and Education: Exploratory Observational Study

For example, older adults often have polypharmacy issues [31], and providers review and deprescribe medications [32]. A specifically trained large language model may provide useful clinical support in polypharmacy management for primary care physicians [29]. Chat GPT has scored better on general and theoretical questions in geriatrics than on complex decisions and end-of-life situations, with the lowest scores related to diagnosis and performing complex tests [30].

Huai Yong Cheng

JMIR Form Res 2025;9:e63494

Phenotyping Adherence Through Technology-Enabled Reports and Navigation (the PATTERN Study): Qualitative Study for Intervention Adaptation Using the Exploration, Preparation, Implementation, and Sustainment Framework

Phenotyping Adherence Through Technology-Enabled Reports and Navigation (the PATTERN Study): Qualitative Study for Intervention Adaptation Using the Exploration, Preparation, Implementation, and Sustainment Framework

Older adults are more likely to have multiple chronic conditions (MCC) and associated polypharmacy [1,2]. As a result, problems with treatment adherence are common; previous estimates have found 30% to 50% of community-dwelling older adults aged 65 years or older demonstrate poor medication adherence [3-5]. These individuals are at subsequent greater risk for suboptimal treatment benefits and adverse drug events [6-8].

Allison P Pack, Stacy C Bailey, Rachel O'Conor, Evelyn Velazquez, Guisselle Wismer, Fangyu Yeh, Laura M Curtis, Kenya Alcantara, Michael S Wolf

JMIR Form Res 2024;8:e54916

Effectiveness of a Mobile App (Meds@HOME) to Improve Medication Safety for Children With Medical Complexity: Protocol for a Randomized Controlled Trial

Effectiveness of a Mobile App (Meds@HOME) to Improve Medication Safety for Children With Medical Complexity: Protocol for a Randomized Controlled Trial

In many cases, they have extreme polypharmacy, medical fragility, and reliance on complicated medication schedules and administration routes all typically managed by undersupported family caregivers [3,4]. A national sample found that CMC in the United States have nearly 5 times higher odds of an adverse drug event leading to an emergency department (ED) visit than other children, and more than 1 of 50 CMC ED visits are due to adverse drug events [5].

Nicole E Werner, Makenzie Morgen, Sophie Kooiman, Anna Jolliff, Gemma Warner, James Feinstein, Michelle Chui, Barbara Katz, Brittany Storhoff, Kristan Sodergren, Ryan Coller

JMIR Res Protoc 2024;13:e60621

A Multimorbidity Analysis of Hospitalized Patients With COVID-19 in Northwest Italy: Longitudinal Study Using Evolutionary Machine Learning and Health Administrative Data

A Multimorbidity Analysis of Hospitalized Patients With COVID-19 in Northwest Italy: Longitudinal Study Using Evolutionary Machine Learning and Health Administrative Data

This approach has the potential to influence future studies and interventions, encompassing areas such as polypharmacy and long COVID-19 research. By deepening our understanding of COVID-19 dynamics, this study emphasizes the broader utility of such methodologies in shaping effective public health strategies and interventions.

Dayana Benny, Mario Giacobini, Alberto Catalano, Giuseppe Costa, Roberto Gnavi, Fulvio Ricceri

JMIR Public Health Surveill 2024;10:e52353

AI Analysis of General Medicine in Japan: Present and Future Considerations

AI Analysis of General Medicine in Japan: Present and Future Considerations

The entry “General medicine in Japan” generated a picture of several drugs (Figure 1), which we interpreted as being indicative of the polypharmacy observed in Japanese medicine. Compared to the rest of the world, Japan is a superaging society. As of 2013, 25% of the population is older than 65 years [6]. Polypharmacy, the combination of various drug therapies for comorbid diseases, is one of the problems seen within an aging society [7]. In Japan, polypharmacy has other causes.

Nozomi Aoki, Taiju Miyagami, Mizue Saita, Toshio Naito

JMIR Form Res 2024;8:e52566

The Use of eHealth for Pharmacotherapy Management With Patients With Respiratory Disease, Cardiovascular Disease, or Diabetes: Scoping Review

The Use of eHealth for Pharmacotherapy Management With Patients With Respiratory Disease, Cardiovascular Disease, or Diabetes: Scoping Review

This is particularly emphasized at times when health care systems are under strain, such as during the SARS-Co V-2 pandemic, and more generally due to the increasing demands of aging populations, in which polypharmacy can be complex to manage [1,2]. e Health is an umbrella term that encompasses different types of electronic technologies, both online and offline, as applied to the domain of health care, broadly defined.

Robbert Bakema, Daria Smirnova, Despina Biri, Janwillem W H Kocks, Maarten J Postma, Lisa A de Jong

J Med Internet Res 2023;25:e42474

The Integration of Clinical Decision Support Systems Into Telemedicine for Patients With Multimorbidity in Primary Care Settings: Scoping Review

The Integration of Clinical Decision Support Systems Into Telemedicine for Patients With Multimorbidity in Primary Care Settings: Scoping Review

Patients with multiple diseases are also usually affected by polypharmacy, requiring more awareness of drug interactions and adverse events [16,17]. Information and communication technology (ICT) has been introduced to help deal with the complexities and challenges of caring for patients with multimorbidity [18]. Common ICT in health care services includes telemedicine and clinical decision support systems (CDSSs).

Nutchar Wiwatkunupakarn, Chanchanok Aramrat, Suphawita Pliannuom, Nida Buawangpong, Kanokporn Pinyopornpanish, Nopakoon Nantsupawat, Poppy Alice Carson Mallinson, Sanjay Kinra, Chaisiri Angkurawaranon

J Med Internet Res 2023;25:e45944

Direct and Indirect Predictors of Medication Adherence With Bipolar Disorder: Path Analysis

Direct and Indirect Predictors of Medication Adherence With Bipolar Disorder: Path Analysis

Thus, polypharmacy with BD is the norm. Given the chronic nature of BD and the importance of treatment [4] to quality of life [5], understanding factors associated with medication adherence is integral to clinical management and long-term well-being. Across mental health conditions, various common factors affect medication adherence, including the number and type of medications prescribed.

Bar Cohen, Andrew Sixsmith, Ariel Pollock Star, Ophir Haglili, Norm O'Rourke

JMIR Form Res 2023;7:e44059