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Noninvasive imaging, such as mammography (MG), low-dose computed tomography (CT) for lung cancer screening (LCS), and CT colonography (CTC), plays important roles in the early detection of the most common cancer types and has demonstrated efficacy in reducing cancer-related and all-cause mortality rates [2,3].
JMIR Cancer 2025;11:e53328
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To objectively assess the function of the lower urinary tract, uroflowmetry and bladder diaries (BD) are commonly used noninvasive examinations for those experiencing LUTS.
Uroflowmetry can measure various parameters during the voiding phase, including maximum flow rate (Qmax), and voided volume, which are essential metrics. Additional parameters, such as flow pattern, time to Qmax, flow time, and average flow rate, provide further insights [1].
Interact J Med Res 2025;14:e66694
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Dermoscopy is a noninvasive technology used to examine the skin’s invisible microstructures in dermatological practice [1]. It is an established technique for analyzing skin lesions, with its origins tracing back to the 17th century when Kohlhaus used a microscope to study nail matrix vessels [1-3]. However, dermoscopy did not gain widespread use until the 20th century, when Goldman developed a portable microscope capable of magnifying up to 10 times more than the naked eye [1-6].
JMIR Dermatol 2025;8:e63861
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AI-Based Noninvasive Blood Glucose Monitoring: Scoping Review
Noninvasive blood glucose monitoring (NIBGM) is ideal for minimizing discomfort, reducing the risk of infection, and increasing convenience. The latest advancements include near-infrared spectroscopy (NIRS), photoplethysmography (PPG), Raman spectroscopy (RS), photoacoustic signals, and biosensors, like saliva and tears [10].
J Med Internet Res 2024;26:e58892
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In recent years, noninvasive prenatal testing (NIPT) has emerged as a safe and effective alternative to invasive methods. NIPT is based on the analysis of cell-free DNA (cf DNA) in the maternal blood [3]. cf DNA is released into the maternal blood by the placenta and contains genetic material from both the mother and the fetus. This advent of NIPT has revolutionized prenatal diagnosis [3].
JMIR Bioinform Biotech 2024;5:e58439
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A noninvasive laboratory method involving measurement of the ratio of soluble FMS-like tyrosine kinase 1 (s FLT-1) to placental growth factor (Pl GF) in the urine proved to be effective in PE diagnosis, achieving a sensitivity of 70%-72.5% with a 5%-14% false-positive rate [22,23]. Thus, combining urine Pl GF and s FLT-1 testing with other biomarkers may yield the best predictive performance.
JMIR Res Protoc 2024;13:e54026
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Moreover, the noninvasive nature of cough audio analysis makes it a convenient and cost-effective diagnostic tool, particularly in resource-constrained settings [12-17]. Patients can record their cough sounds using smartphones or dedicated devices, and these recordings can then be processed by AI algorithms for rapid assessment [20-22].
JMIR Res Protoc 2024;13:e54388
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Innovative Solutions for Patients Who Undergo Craniectomy: Protocol for a Scoping Review
This scoping review will serve as a baseline to provide evidence for multidisciplinary teams currently designing these noninvasive innovations to reduce the risk of associated complications after DC, hoping that more cost-effective models can be implemented, especially in middle-income and low-income countries. The principal limitation of this and any scoping review is the quality of the included studies leaving the included literature with a higher risk of bias.
JMIR Res Protoc 2024;13:e50647
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Specifically, Bangladesh lacks research using ML techniques to predict BGLs based on basic noninvasive clinical measurements and dietary and sociodemographic information. To formulate strategies for public health planning and the control of diabetes, this study aimed to develop a personalized ML model that predicts the BGLs of urban corporate workers in Bangladesh.
JMIR Diabetes 2023;8:e49113
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