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Skip search results from other journals and go to results- 7 JMIR Research Protocols
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It has been shown that the urinary microbiota of patients with interstitial cystitis is less diverse than that of patients without these symptoms [20].
To date, no study has evaluated the modification of the urinary microbiota in patients with radiation cystitis. A better understanding of the impact of the urinary microbiota on the etiopathogenesis of urological disorders may help optimize medical management.
It is also important to note that the microbiota of different organs are linked.
JMIR Res Protoc 2023;12:e38362
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The gut microbiota, or the community of bacteria in the gastrointestinal system, has been shown to display diurnal fluctuations in composition and function, which are both coordinated with host feeding time, the anticipation of nutrient digestion, and energy metabolism [35]. The human gut microbiome is characterized by the bacteria that occupy the digestive tracts of humans in combination with their collective genetic information [36].
JMIR Res Protoc 2022;11(6):e38605
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The composition of gut microbiota differs between subgroups of IBS patients and healthy individuals [16]. This fact, together with an increasing awareness of the importance of a “healthy gut” and the gastrointestinal microbiome, has led to growing research, financial investment, and consumer interest in probiotic treatments that may provide benefits to patients with IBS [17,18].
J Med Internet Res 2021;23(12):e30291
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In this way, the gut microbiota can benefit the host, offering protection from pathogens and supporting immune regulation [2]. However, a dysbiotic gut microbiota is linked to disturbances in metabolic and biological processes, leading to a variety of chronic diseases as well as cancers [3]. Individuals with reduced bacterial richness are characterized by phenotypes such as increased adiposity and insulin resistance [3].
JMIR Res Protoc 2021;10(10):e29046
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This study aims to investigate whether the gut and oral microbiota, or changes in gut and oral microbiota after therapy, are a predictor for treatment response in subjects with active relapsing-remitting MS (RRMS) and whether these changes result in downgrading the immune response. To our knowledge, this is the first study to investigate changes in microbiota and immune response in patients with RRMS in a longitudinal follow-up setting.
JMIR Res Protoc 2020;9(7):e16162
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The human body is home to trillions of microorganisms, primarily bacteria in the gut, which are generally referred to as the microbiota [28]. Commensal gut microbiota dysbiosis is increasingly recognized in the pathogenesis of PD [29]. Therefore, analysis of the commensal gut microbiota and adjusting the intestinal microbiota might be a promising method for the prevention or treatment of PD.
JMIR Res Protoc 2020;9(3):e15759
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For example, transplantation of gut microbiota from obese into germ-free mice has been shown to cause a higher fat mass increase than transplantation of lean microbiota. [3] Thus, altering gut bacterial composition can have a direct effect on body weight. In addition, gut microbiota might play a potential role in the treatment of T2 DM. Indeed, targeting gut microbiota by antibiotic treatment has been shown to improve body weight and glucose tolerance of high-fat fed mice [4,5].
JMIR Res Protoc 2019;8(6):e11553
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Finally, more severe RSV disease has been associated with greater abundance of haemophilus influenzae and streptococcus pneumoniae in the nasal microbiota during RSV infection [38-40].
JMIR Res Protoc 2019;8(6):e12907
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