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Peer Review for “Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study”

Peer Review for “Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study”

The authors have to better describe the different sources of transmission dynamics of COVID-19 (eg, climate, air pollution, etc) and risk factors in society, which can accelerate the diffusion of this novel coronavirus in the environment and the emergence of this hepatic disease in children. After that, they can focus on the topics of this study to provide a correct analysis for fruitful discussion (see suggested readings that must be all read and used in the text). The methods of this study are not clear.

Mario Coccia

JMIRx Med 2024;5:e59596

Authors’ Response to Peer Reviews of “Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study”

Authors’ Response to Peer Reviews of “Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study”

Response: We have revised the title to be more concise and ensure that the abstract clearly outlines the study’s objectives, empirical results, and implications for health and social policy concerning children’s response to COVID-19 and associated hepatic diseases. The introduction has to better clarify the research questions of this study and provide more theoretical background.

Sumit Kumar Rawat, Ajit Anand Asati, Nitu Mishra, Ashish Jain, Radha Kanta Ratho

JMIRx Med 2024;5:e59327

Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study

Identification of COVID-19–Associated Hepatitis in Children as an Emerging Complication in the Wake of SARS-CoV-2 Infections: Ambispective Observational Study

The underlying mechanisms; the role of a cofactor in play, if any; and the respective dominant hepatic phenotype in such cases may have a link with emerging variants of concern including the Delta, Omicron, or further variants [19]. Early identification of such entities is critical for early response, resource allocation, and formulation of guidelines for appropriate management.

Sumit Kumar Rawat, Ajit Anand Asati, Nitu Mishra, Ashish Jain, Radha Kanta Ratho

JMIRx Med 2024;5:e48629

User Engagement, Acceptability, and Clinical Markers in a Digital Health Program for Nonalcoholic Fatty Liver Disease: Prospective, Single-Arm Feasibility Study

User Engagement, Acceptability, and Clinical Markers in a Digital Health Program for Nonalcoholic Fatty Liver Disease: Prospective, Single-Arm Feasibility Study

MRI-PDFF is considered an emerging biomarker for non-invasive hepatic steatosis assessment as it is accurate, precise, quantitative, and reproducible [19]. The SK-241 digital health program was developed by a multidisciplinary group of experts, including a clinical psychologist, nutritionist, behavioral scientists, medical doctors, and nurses at Sidekick Health.

Sigridur Björnsdottir, Hildigunnur Ulfsdottir, Elias Freyr Gudmundsson, Kolbrun Sveinsdottir, Ari Pall Isberg, Bartosz Dobies, Gudlaug Erla Akerlie Magnusdottir, Thrudur Gunnarsdottir, Tekla Karlsdottir, Gudlaug Bjornsdottir, Sigurdur Sigurdsson, Saemundur Oddsson, Vilmundur Gudnason

JMIR Cardio 2024;8:e52576

Perspectives of Inpatients With Cirrhosis and Caregivers on Using Health Information Technology: Cross-sectional Multicenter Study

Perspectives of Inpatients With Cirrhosis and Caregivers on Using Health Information Technology: Cross-sectional Multicenter Study

We screened for inpatients who met the following eligibility criteria: (1) diagnosis of cirrhosis as defined by liver biopsy, overt hepatic decompensation (hepatic encephalopathy, ascites, variceal bleeding, or jaundice), or radiological features of cirrhosis and endoscopic features of varices in patients with chronic liver disease; and (2) those who were admitted nonelectively and had adult cohabitating caregivers.

Chathur Acharya, Tejasav S Sehrawat, Deborah B McGuire, Jawaid Shaw, Andrew Fagan, Sara McGeorge, Amy Olofson, Melanie B White, Edith Gavis, Patrick S Kamath, Lori Bergstrom, Jasmohan Singh Bajaj

J Med Internet Res 2021;23(4):e24639