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Deciphering the Role of Insulin-Like Growth Factor 1 in Endometrial Cancer in Patients With Polycystic Ovary Syndrome: Protocol for a Methodological Approach Using Cell Culture Experiments

Deciphering the Role of Insulin-Like Growth Factor 1 in Endometrial Cancer in Patients With Polycystic Ovary Syndrome: Protocol for a Methodological Approach Using Cell Culture Experiments

Mechanisms thought to increase EC risk in PCOS include raised estrogen levels, obesity, anovulatory menstrual cycles, and unopposed (from progesterone) estrogen stimulation of the endometrium; however, the degree to which these mechanisms increase EC risk or interact with each other to underpin EC risk in PCOS is uncertain [10].

William Atiomo, Fatma Alqutami, Sara Albasha, Mahmood Hachim

JMIR Res Protoc 2023;12:e48127

Pain Reduction With an Immersive Digital Therapeutic Tool in Women Living With Endometriosis-Related Pelvic Pain: Randomized Controlled Trial

Pain Reduction With an Immersive Digital Therapeutic Tool in Women Living With Endometriosis-Related Pelvic Pain: Randomized Controlled Trial

Endometriosis is characterized by lesions occurring outside the uterus whose appearance and behaviors are close to those of the endometrium mainly on the pelvic peritoneum, ovaries, and rectovaginal septum [1]. It might also reach deeper tissues, such as the rectum, bladder, ureters, colon, small bowel, diaphragm, or pelvic nerves.

Benjamin Merlot, Garance Dispersyn, Zoé Husson, Isabella Chanavaz-Lacheray, Thomas Dennis, Juliette Greco-Vuilloud, Maxime Fougère, Stéphane Potvin, Maryne Cotty-Eslous, Horace Roman, Serge Marchand

J Med Internet Res 2022;24(9):e39531