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Development of a Comprehensive Decision Support Tool for Chemotherapy-Cycle Prescribing: Initial Usability Study

Development of a Comprehensive Decision Support Tool for Chemotherapy-Cycle Prescribing: Initial Usability Study

In oncology, electronic patient-reported outcome (e PRO)–based monitoring has gained a great deal of interest in recent years. e PROs have been shown to improve quality of life (Qo L) and survival and reduce the number of unscheduled visits among patients receiving chemotherapy for advanced cancer [4-6].

Sanna Iivanainen, Reetta Arokoski, Santeri Mentu, Laura Lang, Jussi Ekström, Henri Virtanen, Vesa Kataja, Jussi Pekka Koivunen

JMIR Form Res 2025;9:e62749

Leveraging Patient-Reported Outcome Measures for Optimal Dose Selection in Early Phase Cancer Trials

Leveraging Patient-Reported Outcome Measures for Optimal Dose Selection in Early Phase Cancer Trials

Leveraging an electronic PRO (e PRO) solution, using a smartphone app, for example, would enable free-text symptom text to be resurfaced as a list of existing AEs to be easily rescored at future time points. Approaches to simplify adverse event capture and scoring (A) using organ system grouping and (B) collecting the most bothersome adverse events associated with overall impact score.

Bill Byrom, Anthony Everhart, Paul Cordero, Chris Garratt, Tim Meyer

JMIR Cancer 2025;11:e64611

Testing an Electronic Patient-Reported Outcome Platform in the Context of Traumatic Brain Injury: PRiORiTy Usability Study

Testing an Electronic Patient-Reported Outcome Platform in the Context of Traumatic Brain Injury: PRiORiTy Usability Study

The aim of this study was to test the usability of using an e PRO system (Atom5) with individuals who had a TBI. People who had a TBI were recruited in July 2021 from Headway UK, a UK-based charity aiming to promote understanding of all aspects of brain injury and provide information, support and services to survivors, their families and carers.

Christel McMullan, Grace Turner, Ameeta Retzer, Antonio Belli, Elin Haf Davies, Laura Nice, Luke Flavell, Jackie Flavell, Melanie Calvert

JMIR Form Res 2025;9:e58128

Comparison of the Real-World Reporting of Symptoms and Well-Being for the HER2-Directed Trastuzumab Biosimilar Ogivri With Registry Data for Herceptin in the Treatment of Breast Cancer: Prospective Observational Study (OGIPRO) of Electronic Patient-Reported Outcomes

Comparison of the Real-World Reporting of Symptoms and Well-Being for the HER2-Directed Trastuzumab Biosimilar Ogivri With Registry Data for Herceptin in the Treatment of Breast Cancer: Prospective Observational Study (OGIPRO) of Electronic Patient-Reported Outcomes

The historical e PRO data were recorded in the same manner using the earlier versions of the mobile app [11] and were therefore comparable to the prospective e PRO data. This study was approved by the Swiss Institutional Review Board (KEK-ZH: 2021-D0051) and was conducted in accordance with the principles of the Declaration of Helsinki (current version). The study was also registered on Clinical Trials.gov (NCT05234021).

Andreas Trojan, Sven Roth, Ziad Atassi, Michael Kiessling, Reinhard Zenhaeusern, Yannick Kadvany, Johannes Schumacher, Gerd A Kullak-Ublick, Matti Aapro, Alexandru Eniu

JMIR Cancer 2024;10:e54178

Communicating Treatment-Related Symptoms Using Passively Collected Data and Satisfaction/Loyalty Ratings: Exploratory Study

Communicating Treatment-Related Symptoms Using Passively Collected Data and Satisfaction/Loyalty Ratings: Exploratory Study

Real-world studies have demonstrated that an e PRO can facilitate reporting of common treatment symptoms (eg, tiredness, fatigue, and anxiety) compared with standard medical records [6], and a separate study found population level benefit in patients with cancer, including improved 1-, 3-, and 5-year survival [7].

Ian Kudel, Toni Perry

JMIR Cancer 2022;8(2):e29292

How Should Oncologists Choose an Electronic Patient-Reported Outcome System for Remote Monitoring of Patients With Cancer?

How Should Oncologists Choose an Electronic Patient-Reported Outcome System for Remote Monitoring of Patients With Cancer?

Electronic patient-reported outcome (e PRO) systems for symptom monitoring of patients with cancer have had demonstrated quality of life and survival benefits in controlled trials (Table 1). They also result in a reduction of emergency hospitalization and have favorable cost-effectiveness and clinical utility; in addition, users have good perceptions of e PRO systems [1-9].

Fabrice Denis, Ivan Krakowski

J Med Internet Res 2021;23(9):e30549

The Effect of Collaborative Reviews of Electronic Patient-Reported Outcomes on the Congruence of Patient- and Clinician-Reported Toxicity in Cancer Patients Receiving Systemic Therapy: Prospective, Multicenter, Observational Clinical Trial

The Effect of Collaborative Reviews of Electronic Patient-Reported Outcomes on the Congruence of Patient- and Clinician-Reported Toxicity in Cancer Patients Receiving Systemic Therapy: Prospective, Multicenter, Observational Clinical Trial

There is growing interest in integrating electronic PRO (e PRO) into routine clinical practice during chemotherapeutic and immunotherapeutic interventions. Most cancer patients are motivated to spend time and effort documenting symptoms during their consultation for shared reporting with physicians. Patients’ self-empowerment and self-reporting should also improve patient-clinician communication, symptom detection, and symptom control [1].

Andreas Trojan, Nicolas Leuthold, Christoph Thomssen, Achim Rody, Thomas Winder, Andreas Jakob, Claudine Egger, Ulrike Held, Christian Jackisch

J Med Internet Res 2021;23(8):e29271