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COM encompasses various forms, including chronic suppurative otitis media (CSOM) and cholesteatoma, each with unique histological characteristics. CSOM involves the accumulation and discharge of purulent fluid, affecting an estimated 330 million people worldwide, with approximately half experiencing hearing loss [2]. Cholesteatoma is characterized by the buildup of keratinized squamous epithelium, which has the potential to erode auditory structures and exhibits a notable tendency for relapse.
J Med Internet Res 2024;26:e51706
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Eustachian tube obstruction is a common condition that is unpleasant and might lead to various middle ear disorders such as chronic otitis media (OM) and cholesteatoma [2]. Eustachian tube dysfunction (ETD) can be due to intrinsic causes such as anatomical anomalies in the cleft palate, or acquired and extrinsic factors such as an allergic response at the site of the Eustachian tube opening, a viral upper respiratory tract infection, or a combination of intrinsic and extrinsic factors [3].
Interact J Med Res 2020;9(4):e14640
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