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Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study

Feasibility, Acceptability, and Protective Efficacy of Seasonal Malaria Chemoprevention Implementation in Nampula Province, Mozambique: Protocol for a Hybrid Effectiveness-Implementation Study

The World Health Organization (WHO) defines seasonal malaria chemoprevention (SMC) as the intermittent administration of full treatment courses of an antimalarial medicine during the malaria season to prevent malarial illness, with the objective of maintaining therapeutic antimalarial drug concentrations in the blood throughout the period of greatest malarial risk [1-5].

Kevin Baker, Pedro Aide, Craig A Bonnington, Christian Rassi, Sol Richardson, Arantxa Roca-Feltrer, Maria Rodrigues, Mercia Sitoe, Ivan Alejandro Pulido Tarquino, Sonia Enosse, Caitlin McGugan, Eva Amelia de Carvalho, Francisco Saute, Alfredo Gabriel Mayor Aparicio, Baltazar Candrinho

JMIR Res Protoc 2022;11(9):e36403

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Article has an altmetric score of 4

Perceptions of Racially and Ethnically Diverse Women at High Risk of Breast Cancer Regarding the Use of a Web-Based Decision Aid for Chemoprevention: Qualitative Study Nested Within a Randomized Controlled Trial

Perceptions of Racially and Ethnically Diverse Women at High Risk of Breast Cancer Regarding the Use of a Web-Based Decision Aid for Chemoprevention: Qualitative Study Nested Within a Randomized Controlled Trial

Patient-level barriers to chemoprevention uptake include inadequate knowledge and negative attitudes, the fear of potential side effects, and inaccurate perceptions of breast cancer risk [4,12]. Previous studies have found that some women are not aware of the availability of chemoprevention drugs, and less awareness has been noted among racial and ethnic minority women [12]. Women may also be skeptical about the efficacy of chemoprevention in reducing the risk of breast cancer [12].

Tarsha Jones, Ashlee Guzman, Thomas Silverman, Katherine Freeman, Rita Kukafka, Katherine Crew

J Med Internet Res 2021;23(6):e23839

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Development of a Web-Based System for Exploring Cancer Risk With Long-term Use of Drugs: Logistic Regression Approach

Development of a Web-Based System for Exploring Cancer Risk With Long-term Use of Drugs: Logistic Regression Approach

Although little attention has been paid to identifying new chemoprevention drugs from existing available drugs, the strategy of using one drug to treat several indications has shown potential success and become an attractive proposition in many areas of medicine, especially in complex disorders [27]. Aspirin is widely used to treat fever and mild pain, but its long-term use may prevent development of squamous cell carcinoma [28], colorectal cancer [29], and hepatocellular carcinoma [30].

Hsuan-Chia Yang, Md Mohaimenul Islam, Phung Anh Alex Nguyen, Ching-Huan Wang, Tahmina Nasrin Poly, Chih-Wei Huang, Yu-Chuan Jack Li

JMIR Public Health Surveill 2021;7(2):e21401

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Article has an altmetric score of 1