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Amblyopia refers to a unilateral or bilateral decrease of vision caused by abnormal vision development in childhood. It is a common cause of visual impairment in children, significantly affecting their social environment and quality of life. Studies indicate that amblyopia affects 0.7%-2.6% of children aged 30‐71 months and 1%-5.5% of older children [1-3]. Anisometropia is linked to a higher risk of developing amblyopia, with about one-third of children with amblyopia displaying this condition [4].
JMIR Serious Games 2025;13:e63384
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Amblyopia is a global public health problem with multiple impacts on vision and quality of life [1]. Amblyopia, if untreated, leads to permanent visual impairment in adults. The underlying causes are undiscovered anisometropia (unequal refractive error between the 2 eyes), visual deprivation such as congenital or juvenile cataracts, or strabismus with anisometropia. Treatment can be as simple as a pair of glasses.
J Med Internet Res 2024;26:e52401
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Unilateral amblyopia is a developmental disorder resulting in degraded visual acuity in 1 eye. During the developmental phase of vision, degraded stimulation by the weaker eye leads to the underdevelopment of the corresponding cortical visual areas [1]. Amblyopia is associated with poor binocular visual experience in children and has a lasting effect on the individuals’ quality of life, while children with amblyopia are impacted in their daily activities and future job selection [2].
JMIR Pediatr Parent 2023;6:e32282
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Amblyopia is the most common cause of permanent visual impairment in children, and its worldwide prevalence is estimated to be approximately 1.6%-5% [1,2]. Refractive error is one of the leading causes of pediatric amblyopia [3].
JMIR Med Inform 2020;8(5):e16225
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Uncorrected hyperopia can cause blurring of distance vision and near vision and is a known risk factor for the development of strabismus and amblyopia [1]. There is a growing body of evidence that uncorrected hyperopia, in addition to visual consequences, may have a negative impact on educational attainment [2,3] and visuocognitive and visuomotor skills [4].
JMIR Res Protoc 2018;7(9):e173
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