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Exploratory Impact of iCARE Nigeria, a Combined mHealth and Peer Navigation Intervention, on Depressive Symptoms and Substance Use Among Youth Living With HIV in Nigeria: Single-Arm Trial

Exploratory Impact of iCARE Nigeria, a Combined mHealth and Peer Navigation Intervention, on Depressive Symptoms and Substance Use Among Youth Living With HIV in Nigeria: Single-Arm Trial

One of the i CARE Nigeria interventions was a single-arm trial, designed to test the efficacy of a combination of peer navigation and daily SMS text messaging medication reminders in improving medication adherence and viral suppression (defined as plasma HIV-RNA of less than 200 copies/ml) among the youth living with HIV [20]. Participants completed 3 study visits—baseline, 24 weeks, and 48 weeks.

Olusegun Ayomikun Ogunmola, Rita Frinue Tamambang, Kehinde Kuti, Lisa M Kuhns, Olutosin Awolude, Adedotun Adetunji, Bibilola Oladeji, Oladayo Olaleye, Adeola Mary Oyerinde, Robert Garofalo, Babafemi Taiwo, Olayinka Olusola Omigbodun

JMIR Form Res 2025;9:e71141

Usability and Usefulness of SMS-Based Artificial Intelligence Intervention (Mwana) on Breastfeeding Outcomes in Lagos, Nigeria: Pilot App Development Study

Usability and Usefulness of SMS-Based Artificial Intelligence Intervention (Mwana) on Breastfeeding Outcomes in Lagos, Nigeria: Pilot App Development Study

However, further research is needed to explore AI-driven SMS apps for improving breastfeeding support in Nigeria. This research study aims to evaluate the effectiveness of an SMS-based AI app in improving breastfeeding outcomes for mothers in Lagos, Nigeria. The intervention leverages culturally accepted breastfeeding practices in Nigeria while addressing gaps in medical support through an AI-powered virtual assistant.

Anisha Musti

JMIR Form Res 2025;9:e65157

Experiences of Using a Digital Text Messaging Intervention to Support Oral Medication Adherence for People Living With Type 2 Diabetes: Qualitative Process Evaluation

Experiences of Using a Digital Text Messaging Intervention to Support Oral Medication Adherence for People Living With Type 2 Diabetes: Qualitative Process Evaluation

SMS text messages are often perceived by users as a familiar and user-friendly technology requiring limited digital literacy and operating on any kind of mobile telephone. From a health perspective, SMS text messages have a low per-person cost and are routinely used in primary care services in the United Kingdom.

Nikki Newhouse, Yvonne Kiera Bartlett, Sara Correia Simao, Lisa Miles, Rachel Cholerton, Cassandra Kenning, Louise Locock, Veronika Williams, David P French, Rustam Rea, Andrew Farmer

J Med Internet Res 2025;27:e70203

Family Members’ Experiences of a Person-Centered Information and Communication Technology–Supported Intervention for Stroke Rehabilitation (F@ce 2.0): Qualitative Analysis

Family Members’ Experiences of a Person-Centered Information and Communication Technology–Supported Intervention for Stroke Rehabilitation (F@ce 2.0): Qualitative Analysis

Reminders to perform the activities are sent through SMS text messaging each morning. Later in the day, participants receive a new SMS text message asking them to estimate how well the activities were carried out during the day. F@ce 2.0 has been evaluated in a full-scale, nonrandomized, controlled trial (trial registration NCT043511789; manuscript under review). In addition to the ongoing effectiveness study, there is a need to explore how the intervention was experienced by family members [26].

Gunilla Eriksson, Kajsa Söderhielm, Malin Erneby, Susanne Guidetti

JMIR Rehabil Assist Technol 2025;12:e69878

Effectiveness of Text Messaging Nudging to Increase Coverage of Influenza Vaccination Among Older Adults in Norway (InfluSMS Study): Protocol for a Randomized Controlled Trial

Effectiveness of Text Messaging Nudging to Increase Coverage of Influenza Vaccination Among Older Adults in Norway (InfluSMS Study): Protocol for a Randomized Controlled Trial

The primary objectives of the Influ SMS trial are to establish whether (1) influenza vaccination nudging by SMS in the Norwegian language increases influenza vaccine coverage compared to standard care, among the Norwegian population aged 65 years and older; (2) influenza vaccination nudging by SMS in Polish or Ukrainian language increases influenza vaccine coverage compared to standard care, among older adults of Polish or Ukrainian background, respectively; (3) influenza vaccination nudging by SMS in Norwegian

Bo T Hansen, Ole Klungsøyr, Angela S Labberton, Lauri Sääksvuori, Kjersti M Rydland, Liz E Ødeskaug, Torbjørn Wisløff, Hinta Meijerink

JMIR Res Protoc 2025;14:e63938

Patient-Centered mHealth Intervention to Improve Self-Care in Patients With Chronic Heart Failure: Phase 1 Randomized Controlled Trial

Patient-Centered mHealth Intervention to Improve Self-Care in Patients With Chronic Heart Failure: Phase 1 Randomized Controlled Trial

To address this important knowledge gap, our team developed and tested a patient-centered HF self-care intervention (i Cardia4 HF) that integrates 3 commercial m Health apps and devices (My Apps) with a program of individually tailored SMS text messages (Text4 HF) to improve self-care in patients with HF. Tailoring of the text messages was guided by participants’ health beliefs, knowledge, and confidence in performing HF self-care.

Spyros Kitsiou, Ben S Gerber, Susan W Buchholz, Mayank M Kansal, Jiehuan Sun, Susan J Pressler

J Med Internet Res 2025;27:e55586

Don’t Forget the Humble Text Message: 25 Years of Text Messaging in Health

Don’t Forget the Humble Text Message: 25 Years of Text Messaging in Health

In December 1992, the first SMS text message was sent. It contained the words “Merry Christmas” and was sent by a 22-year-old software programmer from the United Kingdom [1]. It took several more years for text messaging to become a standard means of communication from mobile phone to mobile phone. Now, as the most widely used feature on mobile phones, more than 5 billion people send and receive text messages globally [1].

Rosie Dobson, Robyn Whittaker, Lorien C Abroms, Dale Bramley, Caroline Free, Hayden McRobbie, Melanie Stowell, Anthony Rodgers

J Med Internet Res 2024;26:e59888

Qualitative Evaluation of mHealth Implementation for Infectious Disease Care in Low- and Middle-Income Countries: Narrative Review

Qualitative Evaluation of mHealth Implementation for Infectious Disease Care in Low- and Middle-Income Countries: Narrative Review

Among the 20 included studies, 9 were apps and 11 were SMS interventions. Based on the World Bank 2022 Country Group by Income LMIC status [28], 8 were low income [8,9,29-34], 6 were lower middle income [10,35-39], and 6 were upper middle income [7,21,40-43].

Josephine Greenall-Ota, H Manisha Yapa, Greg J Fox, Joel Negin

JMIR Mhealth Uhealth 2024;12:e55189

Evaluating the “Zindagi Mehfooz” Electronic Immunization Registry and Suite of Digital Health Interventions to Improve the Coverage and Timeliness of Immunization Services in Sindh, Pakistan: Mixed Methods Study

Evaluating the “Zindagi Mehfooz” Electronic Immunization Registry and Suite of Digital Health Interventions to Improve the Coverage and Timeliness of Immunization Services in Sindh, Pakistan: Mixed Methods Study

The ZM-EIR includes the following functionalities: Web interface for data visualization Mobile-based data entry and access for vaccinators Geospatial data for vaccination events 2-way interactive SMS reminders for parents/caregivers Call center to answer queries of parents/caregivers Offline mode to work in areas of poor connectivity Child registry for enrolling newborns or never-vaccinated children Immunization decision support system (i DSS) to guide vaccinators on routine and catch-up immunizations Defaulter

Patricia Mechael, Sara Gilani, Ahsan Ahmad, Amnesty LeFevre, Diwakar Mohan, Asra Memon, Mubarak Taighoon Shah, Danya Arif Siddiqi, Subhash Chandir, Riswana Soundardjee

J Med Internet Res 2024;26:e52792