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Quality and Misinformation About Health Conditions in Online Peer Support Groups: Scoping Review
J Med Internet Res 2025;27:e71140
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Using power calculations based on the effect size of a previous iteration of COMET on the 9-item Patient Health Questionnaire (PHQ-9) [38], to detect a small effect of d=0.3, we required 378 participants to complete follow-up. A previous RCT of an SSI in adolescents had an attrition rate of around 28% at 3 months [32]. However, given our shorter follow-up rate of 4 weeks, we raised the recruitment target to 473 to allow for 20% attrition.
J Med Internet Res 2025;27:e58164
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