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French Guiana is the French territory most affected by HIV, with a prevalence >1% in the general population [9]. Most people living with HIV in French Guiana are of foreign origin [10]. Recent studies in French Guiana (one based on the slope of CD4 decline and the other on virus phylogeny) showed that, among the foreign population living with HIV, more than half had been infected in French Guiana [10,11].
JMIR Res Protoc 2025;14:e63586
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Additionally, national HIV epidemiology data reported that the ART treatment rate, based on prescription records in Korea, was 95.5%, and the viral suppression rate was 96%, indicating that most people living with HIV belong to the retention in care [4]. While scientific knowledge of “undetectable equals untransmittable (U=U)” has contributed to transforming HIV into a chronic illness, HIV-related discrimination with stigma remains prevalent in health care settings [5].
JMIR Mhealth Uhealth 2025;13:e60905
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HIV and viral hepatitis remain large public health challenges in the World Health Organization (WHO) European region. An estimated 3 million people are living with HIV, 10.6 million with hepatitis B, and 8.6 million people with hepatitis C [1-3]. In the European region, the public health burden of HIV and hepatitis B and C is particularly high in the Eastern European and Central Asian countries [4].
HIV and viral hepatitis share similar modes of transmission and coinfections are common [5].
JMIR Res Protoc 2025;14:e62929
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The aging global population also includes a growing number of older adults living with HIV [2]. Due to advancements in combination antiretroviral therapy, the life expectancy of people living with HIV has significantly increased [3], leading to the first generation of people living with HIV now reaching geriatric age [4]. This demographic shift brings unique challenges as older adults living with HIV experience a complex interplay of age-related comorbidities and HIV-related health issues [5-7].
JMIR Aging 2025;8:e67122
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HIV programs continue in search of effective interventions to increase adherence to antiretroviral therapy (ART), especially for young people living with HIV/AIDS. This group faces increasing rates of new HIV infections [1] and heightened vulnerability to drivers of antiretroviral resistance, such as suboptimal ART adherence [2], ART abandonment, and non-retention in care [3].
JMIR Res Protoc 2025;14:e66941
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HIV remains a global public health burden, affecting more than 39 million people living with HIV, with approximately 60% of people living with HIV living in sub-Saharan Africa (SSA) [1,2]. HIV/AIDS has claimed 42.3 million lives since the beginning of the epidemic and 630,000 lives in 2023 alone [1]. In addition, the continuous transmission and heightened rates of new HIV infections across different countries remain a significant concern [1,2].
Interact J Med Res 2025;14:e64829
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Stigma Attitudes Toward HIV/AIDS From 2011 Through 2023 in Japan: Retrospective Study in Japan
With the availability of effective antiretroviral treatment, mortality among people with HIV has decreased considerably; in Japan, the 10-year survival rate for people with HIV no longer differs significantly from that for the general population [1]. Further, modern antiretroviral therapy is able to suppress viremia sufficiently to prevent sexual transmission of HIV [2]. Yet, public perception may not necessarily reflect such progress.
J Med Internet Res 2025;27:e69696
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This group is a relatively underreached group that continues to experience HIV-related health disparities at a disproportionate rate; approximately 1 in 3 Black sexually minoritized men are estimated to be diagnosed with HIV by age 50 if current rates persist [18,19].
JMIR Public Health Surveill 2025;11:e64497
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HIV continues to be a global public health concern, with around 1.3 million new HIV infections occurring in 2022 worldwide [1]. Until 2022, there were around 39 million people living with HIV worldwide. HIV imposes a tremendous health and economic burden on the world. Since the epidemic began, more than 40 million lives have been lost due to HIV-related illnesses [2]. Lifelong antiretroviral treatments require long-term health care services and medications [3].
JMIR Public Health Surveill 2025;11:e59519
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HIV remains an important health concern and an area of public health efforts in China, with a particular focus on HIV transmission among gay, bisexual, and other men who have sex with men due to high and sustained risk of HIV infection. A cross-sectional survey of 47,000 men who have sex with men from 61 cities in China in 2008 to 2009 found an overall HIV prevalence of 4.9% [1].
J Med Internet Res 2025;27:e63111
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