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Advancing the Integration of Digital Health Technologies in the Drug Development Ecosystem

Advancing the Integration of Digital Health Technologies in the Drug Development Ecosystem

Addressing these challenges will aid in accelerating the pace at which new developments in DHT-based solutions can be safely integrated into the larger drug development and health care ecosystem. In this viewpoint, we identify some of the major challenges encountered in the integration of DHT-based solutions in the drug development ecosystem and propose practical recommendations that will require collaborative development.

Sakshi Sardar, Cheryl D Coon, Scottie Kern, Huong Huynh, Diane Stephenson, Joshua Rubin Abrams, Grace V Lee, Cecile Ollivier, Joseph A Hedrick, Martijn LTM Müller, Luc J W Evers, Lada Leyens, Collin Hovinga, Shu Chin Ma, Klaus Romero

J Med Internet Res 2025;27:e67052

An Ontology for Digital Medicine Outcomes: Development of the Digital Medicine Outcomes Value Set (DOVeS)

An Ontology for Digital Medicine Outcomes: Development of the Digital Medicine Outcomes Value Set (DOVeS)

Establishing DHT organizational frameworks as ontologies provides a solution to heterogeneity problems like this, thereby defining the concepts and relationships that make interoperability possible [12].

Benjamin Rosner, Matthew Horridge, Guillen Austria, Tiffany Lee, Andrew Auerbach

JMIR Med Inform 2025;13:e67589

Value of Engagement in Digital Health Technology Research: Evidence Across 6 Unique Cohort Studies

Value of Engagement in Digital Health Technology Research: Evidence Across 6 Unique Cohort Studies

While direct comparisons of engagement in personal DHT research are challenging due to the heterogeneous reporting of retention and adherence factors, and a lack of consensus on a definition of “engagement” [3-6], accumulating evidence supports that so far engagement in the use of personal DHTs has been poor. Specifically, retention in personal DHT research studies and the use of health-related apps is low across diverse populations and applications [7-9].

Sarah M Goodday, Emma Karlin, Alexa Brooks, Carol Chapman, Christiana Harry, Nelly Lugo, Shannon Peabody, Shazia Rangwala, Ella Swanson, Jonell Tempero, Robin Yang, Daniel R Karlin, Ron Rabinowicz, David Malkin, Simon Travis, Alissa Walsh, Robert P Hirten, Bruce E Sands, Chetan Bettegowda, Matthias Holdhoff, Jessica Wollett, Kelly Szajna, Kallan Dirmeyer, Anna Dodd, Shawn Hutchinson, Stephanie Ramotar, Robert C Grant, Adrien Boch, Mackenzie Wildman, Stephen H Friend

J Med Internet Res 2024;26:e57827

Revolutionizing Care: Unleashing the Potential of Digital Health Technology in Physiotherapy Management for People With Cystic Fibrosis

Revolutionizing Care: Unleashing the Potential of Digital Health Technology in Physiotherapy Management for People With Cystic Fibrosis

The integration of DHT using pressure sensors embedded in devices may influence physiotherapy assessment and treatment delivery. Using DHTs to guide, counsel, and facilitate goal attainment may enable individualized physiotherapy care for people with CF, offering a flexible approach to modern management, enhancing adherence, and impacting clinical outcomes important to people with CF.

Lisa Morrison, Zoe Louise Saynor, Alison Kirk, Lisa McCann

JMIR Rehabil Assist Technol 2024;11:e55718